Results 141 to 150 of about 482,752 (300)

Identification of a hypoxia-regulated miRNA signature in bladder cancer and a role for miR-145 in hypoxia-dependent apoptosis [PDF]

, 2015
Background: Hypoxia leads to the stabilisation of the hypoxia-inducible factor (HIF) transcription factor that drives the expression of target genes including microRNAs (miRNAs). MicroRNAs are known to regulate many genes involved in tumourigenesis.
A Jones, A L Harris, A Ramachandran, AA Bakkar, B Kou, BW van Rhijn, BW van Rhijn, C Blick, C Blick, C Camps, C Xiao, CC Hudson, CS Neal, CT Lee, CY Chai, D Cranston, DY Lee, E Bernstein, ED Wiklund, F Gottardo, G Ghosh, H Yoshino, HE Gee, IA Babar, J Bauersachs, J Catto, J Ren, JS Aveyard, JW Catto, K Cartharius, KA Cole, KJ Livak, KJ Turner, L Jiang, LA Neely, M Castillo-Martin, M Sachdeva, M Sachdeva, ML Bortolin-Cavaille, MS Ostenfeld, N Xu, NM Luis, OA Kent, PJ Goebell, R Dong, R Hsu, R Kulshreshtha, R McCormick, RK Mutharasan, S Khan, S Noguchi, S Volinia, S Wigfield, T Chiyomaru, U Bruning, VE Theodoropoulos, WG An, X Yan, Z Hua, Z Zhu   +59 more
core   +2 more sources

Bistable Mechanisms 3D Printing for Mechanically Programmable Vibration Control

Advanced Engineering Materials, EarlyView.
This work introduces a 3D‐printed bistable mechanism integrated into tuned mass dampers (TMDs) for mechanically adaptive passive vibration suppression. Through optimized geometry, the bistable design provides adaptable vibration reduction across a broad range of scenarios, achieving effective vibration mitigation without complex controls or external ...
Ali Zolfagharian, Frédéric Demoly, Mohammad Lakhi, Bernard Rolfe, Mahdi Bodaghi   +4 more
wiley   +1 more source

MiR-210 protects cardiomyocytes from OGD/R injury by inhibiting E2F3.

European review for medical and pharmacological sciences, 2018
To detect the change in miRNA-210 expression of cardiomyocytes under hypoxia/reoxygenation status. Also, the effect of miR-210 on the apoptosis of cardiomyocytes induced by oxygen-glucose deprivation/reperfusion (OGD/R) and its mechanism through establishing the OGD/R injury model of primary cardiomyocytes in this experiment were investigated.The cell ...
Bian, W.-S., Shi, P.-X., Mi, X.-F., Sun, Y.-Y., Yang, D.-D., Gao, B.-F., Wu, S.-X., Fan, G.-C.   +7 more
openaire   +2 more sources

Adaptable Tile‐Based Pneumatic Origami through Structurally Coupled Localized Actuation

Advanced Engineering Materials, EarlyView.
This article presents tile‐based pneumatic origami structures with rigid tiles and flexible fabric creases, achieving adaptable properties including morphing shape, selective multistability, and tunable stiffness. Independently pressurized folding bladders at each crease enable structurally coupled localized actuation of origami structures.
Tiantian Li, Jonathan Luntz, Diann Brei
wiley   +1 more source

Dexmedetomidine post-treatment attenuates cardiac ischaemia/reperfusion injury by inhibiting apoptosis through HIF-1α signalling. [PDF]

, 2020
Hypoxia-inducible factor 1α (HIF-1α) plays a critical role in the apoptotic process during cardiac ischaemia/reperfusion (I/R) injury. This study aimed to investigate whether post-treatment with dexmedetomidine (DEX) could protect against I/R-induced ...
Chen, Wei-Rong, Ji, Fu-Hai, Liu, Hong, Liu, Hua-Yue, Meng, Xiao-Wen, Peng, Ke, Xia, Fan, Xia, Zheng-Yuan, Zhang, Juan   +8 more
core  

Investigation of Mir-210 Expression in Breast Cancer Patients

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Breast cancer is one of the most common cancers among women. Abnormal expression of microRNAs is associated with cancer. Therefore, this study aimed to evaluate the expression of miRNA-210 in the serum of breast cancer patients.
Omolbanin Amjadi, Fatemeh Samadi, Reza Alizadeh-Navaei, Reza Valadan, Ehsan Zaboli, Najmeh Ahangar, Elahe Mahmoodi, Akbar Hedayatizadeh-Omran   +7 more
openaire   +1 more source

Manufacturing Continuous Fiber‐Reinforced Printing Filaments: Development of a Post‐Consolidation Unit

Advanced Engineering Materials, EarlyView.
A novel, temperature‐controlled post‐consolidation unit is developed to test its potential to improve the melt impregnation process used to manufacture continuous fiber‐reinforced filaments for additive manufacturing of high‐performance thermoplastics.
Daniel Beermann, Patrick Schiebel, David May   +2 more
wiley   +1 more source

Extracellular vesicles from human cardiac progenitor cells inhibit cardiomyocyte apoptosis and improve cardiac function after myocardial infarction [PDF]

, 2017
Aims Recent evidence suggests that cardiac progenitor cells (CPCs) may improve cardiac function after injury. The underlying mechanisms are indirect, but their mediators remain unidentified.
Barile, Lucio, Cervio, Elisabetta, Gherghiceanu, Mihaela, Lionetti, Vincenzo, Matteucci, Marco, Moccetti, Tiziano, Popescu, Laurentiu M., Siclari, Francesco, Torre, Tiziano, Vassalli, Giuseppe   +9 more
core  

Transfer of Energy and Momentum Between Magnetoactive Surface Microstructure and a Solid Object

Advanced Engineering Materials, EarlyView.
We demonstrate that magnetoactive multilamellar arrays subjected to a rotating magnetic field can function as platforms for controlled transport of physical objects. Through systematic experimental investigation, we elucidate the underlying physical mechanisms determining the upper limit of the achievable transportation speed in such magnetic “conveyor‐
Arne Geldof, Jan Kopačin, Izidor Straus, Raphael Kriegl, Gaia Kravanja, Luka Hribar, Matija Jezeršek, Mikhail Shamonin, Gašper Kokot, Irena Drevenšek‐Olenik   +9 more
wiley   +1 more source

Visualization of exosome-mediated miR-210 transfer from hypoxic tumor cells

Oncotarget, 2016
Cancer cells actively release exosomes carrying specific cellular components, such as proteins, mRNA, and miRNA, to communicate with various cells in the tumor microenvironment. We visualized exosome-mediated transfer of miR-210 from hypoxic breast cancer cells to neighboring cells using a miR-210 specific reporter system.
Jung, Kyung Oh, Youn, Hyewon, Lee, Chul-Hee, Kang, Keon Wook, Chung, June-Key   +4 more
openaire   +3 more sources