Results 1 to 10 of about 14,923 (169)

miR-210-3p protects against osteoarthritis through inhibiting subchondral angiogenesis by targeting the expression of TGFBR1 and ID4 [PDF]

Frontiers in Immunology, 2022
Excessive subchondral angiogenesis is a key pathological feature of osteoarthritis (OA), as it alters the balance of subchondral bone remodeling and causes progressive cartilage degradation.
Han Tang, Wenrun Zhu, Lu Cao, Jin Zhang, Juncheng Li, Duan Ma, Changan Guo   +6 more
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CPEB2 Suppresses Hepatocellular Carcinoma Epithelial–Mesenchymal Transition and Metastasis through Regulating the HIF-1α/miR-210-3p/CPEB2 Axis [PDF]

Pharmaceutics, 2023
Hepatocellular carcinoma (HCC) is a prevalent and high-mortality cancer worldwide, and its complexity necessitates novel strategies for drug selection and design.
Ran You, Yanjun Yang, Guowen Yin, Hao Jiang, Yousheng Lu, Liang Gui, Jun Bao, Qingyu Xu, Liang Feng   +8 more
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miR-210-3p suppresses osteogenic differentiation of MC3T3-E1 by targeting brain derived neurotrophic factor (BDNF) [PDF]

Journal of Orthopaedic Surgery and Research, 2022
Background and objective As an important mediator of intercellular interaction and formation of extracellular bone matrix, porous scaffolds are widely used for bone regeneration.
Li Deng, Shuang Lai, Liyuan Fan, Xinlun Li, Hao Huang, Yandong Mu   +5 more
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Paracrine effects of mir-210-3p on angiogenesis in hypoxia-treated c-kit-positive cardiac cells [PDF]

Annals of Medicine, 2023
Objective: Treatment with c-kit-positive cardiac cells (CPCs) has been shown to improve the prognosis of ischemic heart disease. MicroRNAs (miRNAs) confer protection by enhancing the cardiac repair process, but their specific functional mechanisms remain
Louyi Shen, Guan Fan, Guoliang Yang, Zhijie Yang, Chun Gui   +4 more
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Long Non-coding RNA DLEU2L Targets miR-210-3p to Suppress Gemcitabine Resistance in Pancreatic Cancer Cells via BRCA2 Regulation [PDF]

Frontiers in Molecular Biosciences, 2021
Gemcitabine (GEM) resistance remains a challenging clinical issue to overcome in chemotherapy against pancreatic cancer. We previously demonstrated that miR-210 derived from pancreatic cancer stem cells enhanced the GEM-resistant properties of pancreatic
Fei Xu, Heshui Wu, Jiongxin Xiong, Tao Peng   +3 more
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The Role of miR-375-3p, miR-210-3p and Let-7e-5p in the Pathological Response of Breast Cancer Patients to Neoadjuvant Therapy [PDF]

Medicina, 2022
Background and Objectives: Prediction of response to therapy remains a continuing challenge in treating breast cancer, especially for identifying molecular tissue markers that best characterize resistant tumours.
Lorena Alexandra Lisencu, Andrei Roman, Simona Visan, Eduard-Alexandru Bonci, Andrei Pașca, Emilia Grigorescu, Elena Mustea, Andrei Cismaru, Alexandru Irimie, Cosmin Lisencu, Loredana Balacescu, Ovidiu Balacescu, Oana Tudoran   +12 more
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Hypoxia‐induced miR‐210‐3p expression in lung adenocarcinoma potentiates tumor development by regulating CCL2 mediated monocyte infiltration [PDF]

Molecular Oncology
In most cancers, tumor hypoxia downregulates the expression of C‐C motif chemokine 2 (CCL2), and this downregulation has been implicated in monocyte infiltration and tumor progression; however, the molecular mechanism is not yet clear.
Leena Arora, Debarun Patra, Soumyajit Roy, Sidhanta Nanda, Navneet Singh, Anita K. Verma, Anuradha Chakraborti, Suman Dasgupta, Durba Pal   +8 more
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Study on the mechanism and clinical value of miR-210-3p and miR-582-5p in acute myocardial infarction by targeting MXD1 [PDF]

Journal of Cardiothoracic Surgery
Background Acute myocardial infarction (AMI) occurs rapidly and is a major cause of death in patients with coronary artery disease (CAD). To explore new biomarkers of AMI and its pathogenesis.
Shanshan Liu, Jing Han, Shufang Gao
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Seminal plasma miR-210-3p induces spermatogenic cell apoptosis by activating caspase-3 in patients with varicocele [PDF]

Asian Journal of Andrology, 2020
The aim of this study was to investigate the role of seminal plasma miR-210-3p in the impairment of semen quality caused by varicocele. This study included 102 patients whose semen quality was normal when they were diagnosed with varicocele.
Ya-Wei Xu, Ning-Jing Ou, Yu-Xuan Song, Xian-Hao Wang, Jia-Qi Kang, Yong-Jiao Yang, Ye-Gang Chen, Xiao-Qiang Liu   +7 more
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MiR‐210‐3p is upregulated in diabetic peripheral neuropathy and may be involved in the progression of the disease by targeting brain‐derived neurotrophic factor [PDF]

Journal of Diabetes Investigation
Background Diabetic peripheral neuropathy (DPN), a complication of diabetes, is characterized by complex pathophysiology, high global morbidity, and limited early diagnostic tools. MicroRNAs (miRNAs) have emerged as potential regulators in DPN. Aims This
Yafei Zhao, Liu Wang, Dongcai Feng
doaj   +2 more sources