Results 11 to 20 of about 15,720 (202)

Expression of miR-210-3p as a Prognostic Marker for Development of Diabetic Neuropathy [PDF]

Metabolites
Background/Objectives: Diabetic neuropathy (DN) is one of the most common complications of type 2 diabetes mellitus (T2DM), involving complex metabolic, vascular, and epigenetic mechanisms. MicroRNA-210-3p (miR-210-3p), a hypoxia-responsive molecule, has
Savelia G. Yordanova, Diana Nikolova, Zdravko Kamenov, Vera Karamfilova, Traykov Lachezar, Yavor Assyov, Tsvetan Gatev, Radka Kaneva, Olga Belcheva, Darina Kachakova, Veronika Petkova, Yavor Zhelev, Antoaneta Trifonova Gateva   +12 more
doaj   +4 more sources

Secreted miR-210-3p as non-invasive biomarker in clear cell renal cell carcinoma. [PDF]

Oncotarget, 2017
The most common subtype of renal cell carcinoma (RCC) is clear cell RCC (ccRCC). It accounts for 70-80% of all renal malignancies representing the third most common urological cancer after prostate and bladder cancer.
Petrozza V, Pastore AL, Palleschi G, Tito C, Porta N, Ricci S, Marigliano C, Costantini M, Simone G, Di Carlo A, Gallucci M, Carbone A, Fazi F.   +12 more
europepmc   +8 more sources

Elevation of circulating miR-210-3p in high-altitude hypoxic environment [PDF]

Frontiers in Physiology, 2016
Background: The induction of miR-210-3p, a master hypoxamir, is a consistent feature of the hypoxic response in both normal and malignant cells. However, whether miR-210-3p acts as a circulating factor in response to a hypoxic environment remains unknown.
Yan eYan, Yan eYan, Cheng eWang, Cheng eWang, Wanqing eZhou, Yonghui eShi, Pengtao eGuo, Yuxiu eLiu, Junjun eWang, Chen-Yu eZhang, Chunni eZhang   +10 more
doaj   +5 more sources

Seminal plasma miR-210-3p induces spermatogenic cell apoptosis by activating caspase-3 in patients with varicocele [PDF]

Asian Journal of Andrology, 2020
The aim of this study was to investigate the role of seminal plasma miR-210-3p in the impairment of semen quality caused by varicocele. This study included 102 patients whose semen quality was normal when they were diagnosed with varicocele.
Ya-Wei Xu, Ning-Jing Ou, Yu-Xuan Song, Xian-Hao Wang, Jia-Qi Kang, Yong-Jiao Yang, Ye-Gang Chen, Xiao-Qiang Liu   +7 more
doaj   +4 more sources

Study on the mechanism and clinical value of miR-210-3p and miR-582-5p in acute myocardial infarction by targeting MXD1 [PDF]

Journal of Cardiothoracic Surgery
Background Acute myocardial infarction (AMI) occurs rapidly and is a major cause of death in patients with coronary artery disease (CAD). To explore new biomarkers of AMI and its pathogenesis.
Shanshan Liu, Jing Han, Shufang Gao
doaj   +4 more sources

Down-regulation of miR-210-3p encourages chemotherapy resistance of renal cell carcinoma via modulating ABCC1 [PDF]

Cell & Bioscience, 2018
Background ATP-binding cassette transporter super-family including ABCC1 and MDR-1 were involved in multi-drug resistance (MDR) of renal cell carcinoma (RCC) patients.
Songchao Li, Jinjian Yang, Jun Wang, Wansheng Gao, Yafei Ding, Yinghui Ding, Zhankui Jia   +6 more
doaj   +5 more sources

miR-210-3p enriched extracellular vesicles from hypoxic neuroblastoma cells stimulate migration and invasion of target cells [PDF]

Cell & Bioscience, 2023
Background Tumor hypoxia stimulates release of extracellular vesicles (EVs) that facilitate short- and long-range intercellular communication and metastatization. Albeit hypoxia and EVs release are known features of Neuroblastoma (NB), a metastasis-prone
Pina Fusco, Anna Fietta, Maria Rosaria Esposito, Luca Zanella, Sara Micheli, Angelica Bastianello, Lorenzo Bova, Giulia Borile, Giuseppe Germano, Elisa Cimetta   +9 more
doaj   +4 more sources

Overexpression of miR-210-3p Impairs Extravillous Trophoblast Functions Associated with Uterine Spiral Artery Remodeling [PDF]

International Journal of Molecular Sciences, 2021
Hsa-miR-210-3p has been reported to be upregulated in preeclampsia (PE); however, the functions of miR-210-3p in placental development are not fully understood, and, consequently, miR-210-3p’s role in the pathogenesis of PE is still under investigation. In this study, we found that overexpression of miR-210-3p reduced trophoblast migration and invasion,
Heyam Hayder, Guodong Fu, Lubna Nadeem
exaly   +5 more sources

Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer [PDF]

Biomedicines, 2021
MiRNAs play a relevant role in PC (prostate cancer) by the regulation in the expression of several pathways’ AR (androgen receptor), cellular cycle, apoptosis, MET (mesenchymal epithelium transition), or metastasis.
Luis Javier Martínez-González, Victor Sánchez-Conde, Jose María González-Cabezuelo, Alba Antunez-Rodríguez, Eduardo Andrés-León, Inmaculada Robles-Fernandez, Jose Antonio Lorente, Fernando Vázquez-Alonso, María Jesus Alvarez-Cubero   +8 more
doaj   +4 more sources

MiR‐210‐3p is upregulated in diabetic peripheral neuropathy and may be involved in the progression of the disease by targeting brain‐derived neurotrophic factor [PDF]

Journal of Diabetes Investigation
Background Diabetic peripheral neuropathy (DPN), a complication of diabetes, is characterized by complex pathophysiology, high global morbidity, and limited early diagnostic tools. MicroRNAs (miRNAs) have emerged as potential regulators in DPN. Aims This
Yafei Zhao, Liu Wang, Dongcai Feng
doaj   +2 more sources