Results 31 to 40 of about 15,720 (202)

Serum miR-210-3p can be used to differentiate between patients with pancreatic ductal adenocarcinoma and chronic pancreatitis. [PDF]

Biomed Rep, 2021
Patients with chronic pancreatitis (CP) are at risk of developing pancreatic ductal adenocarcinoma (PDAC). To the best of our knowledge, there are no suitable non-invasive biomarkers for differentiation between CP and PDAC; however, potential molecular candidates include circulating miRNAs due to ease of extraction, their stability and tissue ...
Guz M, Jeleniewicz W, Cybulski M, Kozicka J, Kurzepa J, Mądro A.   +5 more
europepmc   +5 more sources

Antagonistic Roles of the Tumor Suppressor miR-210-3p and Oncomucin MUC4 Forming a Negative Feedback Loop in Pancreatic Adenocarcinoma. [PDF]

Cancers (Basel), 2021
Background: Pancreatic adenocarcinoma (PDAC) is a deadly cancer with an extremely poor prognosis. MUC4 membrane-bound mucin is neoexpressed in early pancreatic neoplastic lesions and is associated with PDAC progression and chemoresistance. In cancers, microRNAs (miRNAs, small noncoding RNAs) are crucial regulators of carcinogenesis, chemotherapy ...
Boukrout N, Souidi M, Lahdaoui F, Duchêne B, Neve B, Coppin L, Leteurtre E, Torrisani J, Van Seuningen I, Jonckheere N.   +9 more
europepmc   +5 more sources

Hypoxic colorectal cancer-secreted exosomes deliver miR-210-3p to normoxic tumor cells to elicit a protumoral effect. [PDF]

Exp Biol Med (Maywood), 2021
Hypoxia, the most common feature in the tumor microenvironment, is closely related to tumor malignant progression and poor patient’s prognosis. Exosomes, initially recognized as cellular “garbage dumpsters”, are now known to be important mediums for mediating cellular communication in tumor microenvironment.
Ge L, Zhou F, Nie J, Wang X, Zhao Q.
europepmc   +3 more sources

MiR-210-3p attenuates lipid accumulation and inflammation in atherosclerosis by repressing IGF2 [PDF]

Bioscience, Biotechnology, and Biochemistry, 2020
ABSTRACT Previous studies have shown that miR-210-3p is involved in the development and progression of atherosclerosis, but its specific mechanisms are still unclear. This study aims to reveal the mechanism of miR-210-3p and its target genes in macrophage lipid deposition and inflammatory response, and provide new ideas for the treatment
Xiang-Rui, Qiao, Liang, Wang, Mengping, Liu, Yuling, Tian, Tao, Chen   +4 more
openaire   +2 more sources

Adipose extracellular vesicles carrying miR-210-3p drive macrophage inflammation and nicotine-induced atherosclerosis. [PDF]

iScience
Li Y, Yang M, Li H, Lei Y, Zhang M, Yang Z, Huang X, Sun Y, Liu Q, Wang X, Hou J.   +10 more
europepmc   +3 more sources

Long non-coding RNA PAXIP-AS1 promotes viability, invasion, and migration of HTR-8/SVneo cells through miR-210-3p/BDNF axis

Hypertension in Pregnancy, 2022
Objective The aim of this research was to explore the role and potential mechanism of long non-coding RNA PAXIP-AS1 in preeclampsia. Methods To investigate the effects of PAXIP-AS1 on cell viability, migration, and invasion.
Xuejuan Chen, Xiang Kong, Gang Niu, Fengjin Qin, Yan Duan, Fengjiao Ren   +5 more
doaj   +1 more source

Emerging role of secreted miR-210-3p as potential biomarker for clear cell Renal Cell Carcinoma metastasis. [PDF]

Cancer Biomark, 2020
BACKGROUND: MicroRNAs (miRNAs) are emerging as promising molecules in the diagnosis, prognosis and treatment of urological tumours. Recently, our group performed two independent studies highlighting that miR-210-3p may be a useful biomarker not only for diagnosis but also for post-surgery clear cell Renal Cell Carcinoma (ccRCC) management.
Petrozza V, Costantini M, Tito C, Giammusso LM, Sorrentino V, Cacciotti J, Porta N, Iaiza A, Pastore AL, Di Carlo A, Simone G, Carbone A, Gallucci M, Fazi F.   +13 more
europepmc   +3 more sources

miR-210-3p regulates the proliferation and apoptosis of non-small cell lung cancer cells by targeting SIN3A. [PDF]

Exp Ther Med, 2019
Previous studies have indicated that microRNA (miR)-210-3p is upregulated in NSCLC, however, the specific mechanism underlying the role of miR-210-3p in NSCLC pathogenesis requires further investigation. The aim of the present study was to explore the roles of miR-210-3p in NSCLC and the associated mechanisms.
Ren J, Li X, Dong H, Suo L, Zhang J, Zhang L, Zhang J.   +6 more
europepmc   +4 more sources

Lung CSC-derived exosomal miR-210-3p contributes to a pro-metastatic phenotype in lung cancer by targeting FGFRL1. [PDF]

J Cell Mol Med, 2020
AbstractLung cancer has the highest mortality rate among human cancers, and the majority of deaths can be attributed to metastatic spread. Lung cancer stem cells (CSCs) are a component of the tumour microenvironment that contributes to this process.
Wang L, He J, Hu H, Tu L, Sun Z, Liu Y, Luo F.   +6 more
europepmc   +4 more sources

MicroRNA-210-3p is transcriptionally upregulated by hypoxia induction and thus promoting EMT and chemoresistance in glioma cells.

PLoS ONE, 2021
BackgroundGlioma is the most common and lethal form of brain cancer. It is highly malignant and is often characterized by chemoresistance and radioresistance, which are thought to mainly result from hypoxic microenvironments. Various tumour-promoting and
Hong Liu, Changjin Chen, Jinhao Zeng, Ziyi Zhao, Qiongying Hu   +4 more
doaj   +1 more source