Hypoxia-Induced MicroRNA-210 Targets Neurodegenerative Pathways [PDF]
Non-coding RNA, 2018 Hypoxia-regulated microRNA-210 (miR-210) is a highly conserved microRNA, known to regulate various processes under hypoxic conditions. Previously we found that miR-210 is also involved in honeybee learning and memory, raising the questions of how neural ...
Michelle Watts +2 more
exaly +9 more sources
MicroRNA-210 regulates the metabolic and inflammatory status of primary human astrocytes [PDF]
Journal of Neuroinflammation, 2022 Background Astrocytes are the most numerous glial cell type with important roles in maintaining homeostasis and responding to diseases in the brain. Astrocyte function is subject to modulation by microRNAs (miRs), which are short nucleotide strands that ...
Nicholas W. Kieran +13 more
doaj +5 more sources
Analysis of differential expression of hypoxia-inducible microRNA-210 gene targets in mild and severe preeclamptic patients [PDF]
Non-coding RNA Research, 2021 Preeclampsia (PE) is a multi-system disorder that is specific to human pregnancy. Inadequate oxygenation of uterus and placenta is considered as one of the leading causes for the disease.
Zainab H Malalla, Sameh Sarray
exaly +4 more sources
MicroRNA-210 May Be a Preoperative Biomarker of Malignant Pheochromocytomas and Paragangliomas [PDF]
Journal of Surgical Research, 2019 Currently, no reliable predictive clinical or laboratory tests exist that can accurately distinguish between benign and malignant pheochromocytomas or paragangliomas (PPGLs). The aim of this study was to investigate if serum microRNA-210 (miR-210) levels could be a marker of malignancy in patients with PPGLs.Preoperative serum from patients with PPGLs ...
Samantha M Ruff +2 more
exaly +5 more sources
MicroRNA-210 Regulates Endoplasmic Reticulum Stress and Apoptosis in Porcine Embryos [PDF]
Animals, 2021 Endoplasmic reticulum (ER) stress can be triggered during in vitro embryo production and is a major obstacle to embryo survival. MicroRNA (miR)-210 is associated with cellular adaptation to cellular stress and inflammation. An experiment was conducted to
Muhammad Rosyid Ridlo +2 more
doaj +5 more sources
Kynurenine–PARP-1 Link Mediated by MicroRNA 210 May Be Dysregulated in Pulmonary Hypertension [PDF]
Anatolian Journal of Cardiology, 2022 Background: Dysregulation of microRNAs is associated with pulmonary hypertension. The present study aimed to determine the alterations in microRNA and microRNA expressions and their role in signaling pathways and investigate the relationship with serum ...
Alperen Emre Akgun +4 more
doaj +2 more sources
Association of microRNA-210-3p with NT-proBNP, sST2, and Galectin-3 in heart failure patients with preserved and reduced ejection fraction: A cross-sectional study. [PDF]
PLoS ONEBackgroundHeart failure (HF) is a growing health problem and around two percent are affected in the general population. Accurate diagnostic markers that have the potential for early diagnosis of HF are lacking.
Jasmine Chandra Arul +5 more
doaj +2 more sources
Urinary microRNA-210-3p as a novel and non-invasive biomarker for the detection of pancreatic cancer, including intraductal papillary mucinous carcinoma [PDF]
BMC CancerBackground This study aims to explore novel microRNAs in urine for screening and predicting clinical characteristics in pancreatic cancer (PC) patients using a microRNA array-based approach.
Taisuke Imamura +11 more
doaj +2 more sources
MicroRNA-210 and its theranostic potential
Expert Opinion on Therapeutic Targets, 2016 MicroRNAs (miRNAs) are a set of small single-stranded noncoding RNAs with diverse biological functions. As a prototypical hypoxamir, human microRNA-210 (hsa-miR-210) is one of the most widely studied miRNAs thus far. In addition to its involvement in sophisticated regulation of numerous biological processes, miR-210 has also been shown to be associated
Rui-Xue Leng +2 more
exaly +6 more sources
The Role of microRNA-210 in the Pathogenesis and Diagnosis of Preeclampsia-A Systematic Review. [PDF]
J Clin MedBackground: Preeclampsia is a complex hypertensive disorder of pregnancy associated with significant maternal and foetal morbidity and mortality. Its pathogenesis involves placental hypoxia, oxidative stress, and impaired trophoblast invasion. Recent evidence highlights the role of microRNAs, particularly microRNA-210 (miR-210), in the molecular ...
Cretu OE +4 more
europepmc +3 more sources