MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease [PDF]
Circulation, 2010 Background— MicroRNAs are involved in various critical functions, including the regulation of cellular differentiation, proliferation, angiogenesis, and apoptosis. We hypothesize that microRNA-210 can rescue cardiac function after myocardial infarction by upregulation of angiogenesis and inhibition ...
Shijun Hu, Zongjin Li, Fangjun Jia
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MicroRNA‐210 targets FBXO31 to inhibit tumor progression and regulates the Wnt/β‐catenin signaling pathway and EMT in esophageal squamous cell carcinoma [PDF]
Thoracic Cancer, 2021 Evidence from previous studies showed that the dysregulation of microRNA (miR) is frequently associated with tumor progression. The aberrant miR‐210 expression has been identified in a variety of tumors.
Jing Meng +5 more
doaj +2 more sources
MicroRNA-210 Mediates Hypoxic Pulmonary Hypertension in the Newborn Lamb. [PDF]
HypertensionBACKGROUND: Pulmonary hypertension of the newborn is a life-threatening disorder characterized by elevated pulmonary vascular resistance due to maladaptation of the pulmonary circulation after birth. The pathogenesis and mechanisms underlying pulmonary hypertension of the newborn remain unclear, hindering the ...
Hu XQ +8 more
europepmc +3 more sources
microRNA‐210 in red blood cells differentially regulates vascular endothelial function between type 1 and type 2 diabetes [PDF]
Physiological ReportsRed blood cells from individuals with type 2 diabetes (T2D RBC) induce endothelial dysfunction due to reduced RBC microRNA‐210 levels, whereas T1D RBCs do not. We hypothesize that microR‐210 plays a protective role explaining this difference.
Tong Jiao +11 more
doaj +2 more sources
MicroRNA-210 Enhances Cell Survival and Paracrine Potential for Cardiac Cell Therapy While Targeting Mitophagy [PDF]
Journal of Functional BiomaterialsThe therapeutic potential of presumed cardiac progenitor cells (CPCs) in heart regeneration has garnered significant interest, yet clinical trials have revealed limited efficacy due to challenges in cell survival, retention, and expansion.
Rita Alonaizan +6 more
doaj +2 more sources
Evaluation of microRNA-10a and microRNA-210 as Biomarkers in Sepsis Patients With Acute Kidney Injury [PDF]
International Journal of NephrologyConclusion: The study’s findings revealed a significant increase in miR-210-3p expression in sepsis patients with AKI, indicating its potential as a promising biomarker for determining AKI.
Hani Susianti +6 more
doaj +2 more sources
Serum microRNA-210 as a potential noninvasive biomarker for the diagnosis and prognosis of glioma [PDF]
British Journal of Cancer, 2015 MicroRNA-210 (miR-210) is an oncogenic miRNA previously associated with prognosis in human gliomas, an incurable tumour type of the central nervous system. Here miR-210 was investigated as a potential serum biomarker in the diagnosis and prognosis of glioma.Serum was immediately prepared from blood samples collected from patients with glioma grades I ...
Lin Y-C
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Endocrine Delivery of MicroRNA-210: A Trusted Traveler That Mediates Pulmonary Hypertension. [PDF]
Circ Res, 2020 Leopold JA.
europepmc +4 more sources
MicroRNA-210 Controls Mitochondrial Metabolism and Protects Heart Function in Myocardial Infarction [PDF]
Circulation, 2022 Rui Song +2 more
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Neurobiology of Disease, 2016 Perinatal hypoxic–ischemic encephalopathy (HIE) is associated with high neonatal mortality and severe long-term neurologic morbidity. Yet the mechanisms of brain injury in infants with HIE remain largely elusive.
Qingyi Ma +2 more
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