Results 151 to 160 of about 482,752 (300)

Engineering Deformation and Failure in Diamond Triply Periodic Minimal Surface Lattices via 3D Wall‐Thickness Grading

Advanced Engineering Materials, EarlyView.
The work demonstrates that strategic wall‐thickness grading in diamond triply periodic minimal surface lattices enables precise tuning of deformation and failure behavior under compression. Different gradation patterns guide how and where the structure collapses, improving energy absorption or promoting controlled brittle failure.
Giovanni Rizza, Danilo Bruson, Manuela Galati, Luca Iuliano   +3 more
wiley   +1 more source

Down-regulation of miR-210-3p encourages chemotherapy resistance of renal cell carcinoma via modulating ABCC1

Cell & Bioscience, 2018
Background ATP-binding cassette transporter super-family including ABCC1 and MDR-1 were involved in multi-drug resistance (MDR) of renal cell carcinoma (RCC) patients.
Songchao Li, Jinjian Yang, Jun Wang, Wansheng Gao, Yafei Ding, Yinghui Ding, Zhankui Jia   +6 more
doaj   +1 more source

Pregnancy-associated cardiac dysfunction and the regulatory role of microRNAs. [PDF]

, 2020
Many crucial cardiovascular adaptations occur in the body during pregnancy to ensure successful gestation. Maladaptation of the cardiovascular system during pregnancy can lead to complications that promote cardiac dysfunction and may lead to heart ...
Aryan, Laila, Eghbali, Mansoureh, Medzikovic, Lejla, Umar, Soban   +3 more
core  

3D‐Printed Serial Snap‐Through Architectures for Programmable Mechanical Response

Advanced Engineering Materials, EarlyView.
A serial snap‐through architecture is realized using compact 3D‐printed von Mises truss units arranged in a staged cascade. Their geometry and boundary conditions program multistage mechanical responses with plateaux and re‐hardening regimes. An inverted‐compliance model predicts these behaviors and enables analytical design of programmable force ...
Filipe A. Santos
wiley   +1 more source

miRNAs link metabolic reprogramming to oncogenesis [PDF]

, 2013
The most profound biochemical phenotype of cancer cells is their ability to metabolize glucose to lactate, even under aerobic conditions. This alternative metabolic circuitry is sufficient to support the biosynthetic and energy requirements for cancer ...
Hatziapostolou, M, Iliopoulos, D, Polytarchou, C   +2 more
core   +1 more source

Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer

Translational Oncology, 2010
MicroRNA are small noncoding transcripts involved in many cellular mechanisms, including tumorigenesis. miR-210, in particular, is induced by hypoxia and correlates with adverse outcomes in certain cancers. Because pancreatic adenocarcinomas exhibit extremely hypoxic signatures, we hypothesized that miR-210 may serve as a diagnostic marker for ...
Ho, Allen S., Huang, Xin, Cao, Hongbin, Christman-Skieller, Claudia, Bennewith, Kevin, Le, Quynh-Thu, Koong, Albert C.   +6 more
openaire   +2 more sources

Unique Performance Considerations for Printable Organic Semiconductor and Perovskite Radiation Detectors: Toward Consensus on Best Practice Evaluation

Advanced Functional Materials, EarlyView.
A lack of standard approaches for testing and reporting the performance of metal halide perovskites and organic semiconductor radiation detectors has resulted in inconsistent interpretation of performance parameters, impeding progress in the field. This Perspective recommends key metrics and experimental details, which are suggested for reporting in ...
Jessie A. Posar, Matthew Large, Andrea Ciavatti, Laura Basiricò, Beatrice Fraboni, Paul J. Sellin, Attila J. Mozer, Marco Petasecca, Matthew J. Griffith   +8 more
wiley   +1 more source

Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif [PDF]

, 2013
MicroRNAs modulate tumorigenesis through suppression of specific genes. As many tumour types rely on overlapping oncogenic pathways, a core set of microRNAs may exist, which consistently drives or suppresses tumorigenesis in many cancer types.
Coarfa, Cristian, Ding, Li, Gunaratne, Preethi H., Hamilton, Mark P., Hartig, Sean M., Kandoth, Cyriac, McGuire, Sean E., McLellan, Michael D., Rajapakshe, Kimal, Reva, Boris, Wheeler, David A., Zack, Travis I.   +11 more
core   +3 more sources

Organic Electrochemical Transistor Channel Materials: Copolymerization Versus Physical Mixing of Glycolated and Alkoxylated Polymers

Advanced Functional Materials, EarlyView.
This work discusses the use of blended channel materials in OECTs. It explores how mixing glycolated and alkoxylated polymers in various ratios offers a simpler and more efficient route to tuning OECT properties. The performance of the polymer blends is compared to the corresponding copolymers, demonstrating similar OECT characteristics, swelling ...
Lize Bynens, Kaishuai Zhang, Priscila Cavassin, Arwin Goossens, Jochen Vanderspikken, Tania C. H. Castillo, Demetra Tsokkou, Adam Marks, Arianna Magni, Karrie Weaver, Laurence Lutsen, Sahika Inal, Koen Vandewal, Natalie Banerji, Wouter Maes   +14 more
wiley   +1 more source

Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs [PDF]

, 2012
In order to understand the role of microRNAs (miRNAs) in vascular physiopathology, we took advantage of deep-sequencing techniques to accurately and comprehensively profile the entire miRNA population expressed by endothelial cells exposed to hypoxia ...
Brini, Elena, Capogrossi, Maurizio C., Croft, Larry, David, Matei, Fasanaro, Pasquale, Felsani, Armando, Guffanti, Alessandro, Isaia, Eleonora, Martelli, Fabio, Moles, Anna, van Rooij, Jeroen, Voellenkle, Christine   +11 more
core   +1 more source