Results 111 to 120 of about 45,933 (126)

Transcriptomics driven identification of hub gene miRNA interactions for biomarker and therapeutic target discovery in gynecological cancers. [PDF]

Front Oncol
Zhu Y, Chen S, Cao M, Liu W, Huang H, Huang K, Shi L.   +6 more
europepmc   +1 more source

In vivo AGO-APP for cell-type- and compartment-specific miRNA profiling in the mouse brain. [PDF]

Cell Rep Methods
Kapoor S, Erni A, Vincenzi F, Tessier B, Venugopal V, Meister G, Favereaux A, Cremer H, Beclin C.   +8 more
europepmc   +1 more source

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Circular RNA circ_0000741/miR-379-5p/TRIM14 signaling axis promotes HDAC inhibitor (SAHA) tolerance in glioblastoma

Metabolic Brain Disease, 2023
Histone deacetylase (HDAC) inhibitor-based therapeutic drug tolerance is a major obstacle to glioblastoma (GBM) treatment. Meanwhile, non-coding RNAs have been reported to be involved in the regulation of HDAC inhibitor (SAHA) tolerance in some human tumors. However, the relationship between circular RNAs (circRNAs) and SAHA tolerance is still unknown.
Liang Meng, Yuefei Wang, Qin Tu, Yuan Zhu, Xiaoqin Dai, Ji Yang   +5 more
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Circ_0011292 Enhances Paclitaxel Resistance in Non-Small Cell Lung Cancer by Regulating miR-379-5p/TRIM65 Axis

Cancer Biotherapy and Radiopharmaceuticals, 2022
Background: Non-small cell lung cancer (NSCLC) is the most prevalent cancer in the world. Chemotherapy resistance is a major obstacle to NSCLC therapy. This study explored the role and molecular mechanism of circular RNA 0011292 (circ_0011292) in tumorigenesis and chemoresistance of NSCLC. Methods: The levels of circ_0011292, miR-379-5p, and tripartite
Chunhong, Guo, Hailiang, Wang, Housen, Jiang, Liang, Qiao, Xinli, Wang   +4 more
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Circ_SIPA1L1 Promotes Osteosarcoma Progression Via miR-379-5p/MAP3K9 Axis

Cancer Biotherapy and Radiopharmaceuticals, 2023
Background: Osteosarcoma (OS) is a common malignant bone tumor. Circular RNAs (circRNAs) exert important roles in the pathogenesis of human cancers, including OS. In this study, the authors focused on the role and mechanism of circRNA signal-induced proliferation-associated 1 like 1 (circ_SIPA1L1) in OS. Methods: The enrichment of SIPA1L1, circ_SIPA1L1,
Liu, Jun, Li, Xuhong, Liu, Hui
openaire   +3 more sources

CircRNA_0088196 Regulates Trophoblast Proliferation and Apoptosis in Preeclampsia Through the miR-379-5p/HSPA5 Axis

Biochemical Genetics, 2023
Existing research has confirmed the dysregulation of circular RNA (circRNA) in a wide variety of human diseases. Thus, in this study, we explored the potential mechanism of circRNA_0088196 in preeclampsia (PE). We performed quantitative real-time PCR to examine circRNA_0088196 expression and verified the function of circRNA_0088196 in vitro using CCK-8,
Zhihui, Xiong, Qingmin, Wang, Shuping, Pei, Huiling, Zheng, Wei, Wang   +4 more
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MiR-379–5p targets microsomal glutathione transferase 1 (MGST1) to regulate human glioma in cell proliferation, migration and invasion and epithelial-mesenchymal transition (EMT)

Biochemical and Biophysical Research Communications, 2021
Glioma is one of the most malignant tumors worldwide. This study was aimed to study the effect of miR-379-5p/MGST1 on cell proliferation, migration, invasion and EMT in glioma.RT-qPCR detected the expression of miR-379-5p and MGST1 in RNA level in glioma cell lines.
Baoyi Yang, Shitao Xia, Xiangmei Ye, Wei Jing, Beifeng Wu   +4 more
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Circ_0002984 Enhances Growth, Invasion, and Migration in PDGF-bb–Induced Vascular Smooth Muscle Cells Through miR-379-5p/FRS2 Axis

Journal of Cardiovascular Pharmacology, 2021
Abstract: The accumulation of vascular smooth muscle cells (VSMCs) is considered to play important roles in atherosclerosis (AS) development and progression. Circ_0002984 was found to be increased in oxidized low-density lipoprotein (ox-LDL) human VSMCs (HVSMCs).
Xiangni, Zheng, Jian, Liu, Xuepeng, Gong, Xu, Zhang, Shengting, Ma   +4 more
openaire   +3 more sources