Results 111 to 120 of about 3,800 (160)

MicroRNA binding site variants–new potential markers of primary osteoporosis in men and women [PDF]

open access: yes
IntroductionThe identification of significant DNA markers of primary osteoporosis may gain new insights by studying genome regions involved in mechanisms of epigenetic regulation through interactions with microRNAs.MethodsThe authors searched for ...
Anna Eremkina   +9 more
core   +1 more source

Exosomal MicroRNA Signatures in Central Nervous System Diseases [PDF]

open access: yes, 2018
During the last decade there has been a growing interest in studying extracellular vesicles, in particular exosomes and their miRNA contents. Exosomes are released by almost all cell types.
Ebrahimkhani, Saeideh
core  

MiRNA调控脑缺血/再灌注诱导的自噬信号通路研究进展 [PDF]

open access: yes
脑卒中时缺血缺氧致脑组织功能损伤,且缺血后脑组织再恢复血液供应时,大量自由基、钙超载等引起脑缺血/再灌注损伤,进一步加重病情。自噬是一种维持细胞内环境稳态的自我保护机制,但过度自噬引起脑组织损伤。MiRNA为小的内源性非编码RNA分子,通过与其靶基因mRNA的3’ -UTR中的互补序列结合,导致翻译抑制或mRNA降解,从基因水平上调控多种生理活动。MiRNA不仅直接作用于自噬相关蛋白,还可通过多种信号通路,参与缺血/再灌注诱导的自噬调控。但关于miRNA调控脑缺血 ...
刘筱蔼, 罗友根
core   +1 more source

Integrative Review of Molecular, Metabolic, and Environmental Factors in Spina Bifida and Congenital Diaphragmatic Hernia: Insights into Mechanisms and Emerging Therapeutics

open access: yesCells
Spina Bifida (SB) and Congenital Diaphragmatic Hernia (CDH) are complex congenital anomalies that pose significant challenges in pediatric healthcare. This review synthesizes recent advancements in understanding the genetic, metabolic, and environmental ...
Angelika Buczyńska   +4 more
doaj   +1 more source

MicroRNA profiling of the feline left heart identifies chamber-specific expression signatures in health and in advanced hypertrophic cardiomyopathy [PDF]

open access: yes, 2023
Caswell, Jeff L   +6 more
core   +1 more source

2025 ACVIM Forum Research Abstract Program

open access: yes
Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
wiley   +1 more source

Hledání cirkulujících biomarkerů charakterizujících časnou axiální spondylartritidu a její progresi [PDF]

open access: yes
Axial spondyloarthritis (axSpA) is a chronic autoimmune disease primarily affecting the spine and sacroiliac joints. It presents with chronic back pain, sacroiliitis, arthritis, and other skeletal and extra-skeletal inflammatory symptoms.
Mocová, Klára
core  

ヒト肺腺癌におけるマイクロRNA編集の異常と臨床病理学的検討 [PDF]

open access: yes, 2018
学位の種別: 課程博士審査委員会委員 : (主査)東京大学教授 中島 淳, 東京大学准教授 滝田 順子, 東京大学准教授 織田 克利, 東京大学講師 田中 哲洋, 東京大学講師 大塚 基之University of Tokyo ...
Maemura Keita, 前村 啓太
core   +1 more source

miR-379-5p regulates the proliferation, cell cycle, and cisplatin resistance of oral squamous cell carcinoma cells by targeting ROR1.

open access: yesAmerican journal of translational research
To analyze the regulatory mechanism microRNA miR-379-5p in oral squamous cell carcinoma (OSCC).We collected serum samples from patients with OSCC and examined the expression of miR-379-5p and receptor tyrosine kinase-like orphan receptor 1 (ROR1) by real-time polymerase chain reaction and western blot.
Lei, Meng   +3 more
openaire   +1 more source

Home - About - Disclaimer - Privacy