Results 101 to 110 of about 4,116 (175)

Differentiation-Associated MicroRNA Alterations in Mouse Heart-Derived Sca-1 + [PDF]

, 2016
Cardiac resident stem/progenitor cells (CSC/CPCs) are critical to the cellular and functional integrity of the heart because they maintain myocardial cell homeostasis.
Jinxi Zhan, Juan Yu, Lu Xu, Qiong Wu, Shiming Pu, Xiaoxia Wang, Yun Li, Zuping Zhou   +7 more
core   +2 more sources

Melanoma: Pathogenesis and Targeted Therapy

MedComm, Volume 7, Issue 1, January 2026.
The treatment landscape for advanced melanoma has evolved significantly. BRAF–MEK inhibitor combinations are standard for BRAF‐mutant melanoma, whereas targeting NRAS mutations is more challenging, with MEK inhibitors like tunlametinib emerging as an option.
Yang Fu, Jie Liu, Zeming Mo, Bin Wang, Yaotiao Deng, Yu Jiang   +5 more
wiley   +1 more source

A comprehensive method for identification of suitable reference genes in extracellular vesicles

Journal of Extracellular Vesicles, 2017
Reverse transcription–quantitative polymerase chain reaction (RT-qPCR) is one of the most sensitive, economical and widely used methods for evaluating gene expression.
Kenneth Gouin, Kiel Peck, Travis Antes, Jennifer Leigh Johnson, Chang Li, Sharon Denise Vaturi, Ryan Middleton, Geoff de Couto, Ann-Sophie Walravens, Luis Rodriguez-Borlado, Rachel Ruckdeschel Smith, Linda Marbán, Eduardo Marbán, Ahmed Gamal-Eldin Ibrahim   +13 more
doaj   +1 more source

The role of microRNAs in congenital heart disease [PDF]

, 2019
L
Baráth, Sándor, Nagy, Orsolya, Ujfalusi, Anikó   +2 more
core  

Bioinformatics prioritization of SNPs perturbing microRNA regulation of hematological malignancy-implicated genes. [PDF]

, 2015
The contribution of microRNAs (miRNAs) to cancer has been extensively investigated and it became obvious that a strict regulation of miRNA-mRNA regulatory network is crucial for safeguarding cell health.
Abolfazl Movafagh, Andrea Masotti, Behnam Alipoor, Davood Zare-Abdollahi, Hamid Ghaedi, Milad Bastami, Mir Davood Omrani, Reza Mirfakhraie   +7 more
core   +1 more source

miRNA-based regulation in growth plate cartilage: mechanisms, targets, and therapeutic potential [PDF]

MicroRNAs (miRNAs) are critical regulators of the skeleton. In the growth plate, these small non-coding RNAs modulate gene networks that drive key stages of chondrogenesis, including proliferation, differentiation, extracellular matrix synthesis and ...
Anne M. Delany, Prachi Thakore
core   +1 more source

The miR-15b-5p/miR-379-3p-FOXO axis regulates cell cycle and apoptosis in scleral remodeling during experimental myopia

Journal of Translational Medicine
Background Myopia is one of the most common eye diseases in children and adolescents worldwide, and scleral remodeling plays a role in myopia progression.
Ruixue Zhang, Ying Wen, Jinpeng Liu, Jiawen Hao, Yuan Peng, Miao Zhang, Yunxiao Xie, Zhaohui Yang, Xuewei Yin, Yongwei Shi, Hongsheng Bi, Dadong Guo   +11 more
doaj   +1 more source

CircRNA PDE3B regulates tumorigenicity via the miR-136-5p/MAP3K2 axis of esophageal squamous cell carcinoma [PDF]

, 2023
Background. CircRNA has a covalently closed circular conformation and a stable structure. However, the exact role of circRNA in esophageal squamous cell carcinoma (ESCC) remains uncertain.
Chen, Baokun, Hui, Gang, Wang, He, Wu, Da, Ye, Yiwang, Yue, Wei   +5 more
core  

Transcriptomic analysis revealed that oar-miR-370-3p was involved in the regulation of wool fineness in Ordos fine-wool sheep [PDF]

MicroRNA (miRNA) is a prominent topic in biological research, as it plays a crucial role in regulating various physiological processes. Identifying miRNAs associated with fiber traits enhances our understanding of the complex biological mechanisms ...
Asma Anwar, Cuiling Wu, Gvlnigar Amar, Sen Tang, Shengchao Ma, Shengchao Ma, Wenna Liu, Xuefeng Fu   +7 more
core   +1 more source

Sources of Individual Variability: Mirnas That Predispose to Neuropathic Pain Identified Using Genome-Wide Sequencing

Molecular Pain, 2014
Background: We carried out a genome-wide study, using microRNA sequencing (miRNA-seq), aimed at identifying miRNAs in primary sensory neurons that are associated with neuropathic pain. Such scans usually yield long lists of transcripts regulated by nerve
Kiran Kumar Bali, Michael Hackenberg, Avigail Lubin, Rohini Kuner, Marshall Devor   +4 more
doaj   +1 more source