Results 141 to 150 of about 319,034 (267)

MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus

BMC Neuroscience, 2012
Background The expression pattern and function of miRNAs in the rat model of temporal lobe epilepsy have not been well defined. Profiling miRNA expression in the rat model of temporal lobe epilepsy and investigating the function of specific miRNAs in ...
Hu Kai, Xie Yuan-Yuan, Zhang Chen, Ouyang Dong-Sheng, Long Hong-Yu, Sun Dan-Ni, Long Li-Li, Feng Li, Li Yi, Xiao Bo   +9 more
doaj   +1 more source

Tb3+‐Doped Glass‐Ceramic Scintillating Plates and Fibers for X‐Ray Imaging and Flexible Detection

Advanced Science, EarlyView.
A Tb3+‐doped glass‐ceramic scintillator, with controlled Ba2GdF7 nanocrystal precipitation, was developed through a rational design strategy guided by phase diagrams and molecular dynamics simulations. The obtained material exhibits a high light yield of 41 800 photons/MeV (418%/BGO), a spatial resolution of 25.3 lp/mm, and exceptional thermal ...
Songxuan Liu, Ping Zhang, Panpan Li, Yao Ji, Zhiguo Xia, Weichao Wang, Qinyuan Zhang   +6 more
wiley   +1 more source

AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes [PDF]

, 2019
Wurood Hantoosh Neamah, Narendra P. Singh, Hasan Alghetaa, Osama A. Abdulla, Saurabh Chatterjee, Philip Brandon Busbee, Mitzi Nagarkatti, Prakash Nagarkatti   +7 more
openalex   +1 more source

Sequencing identifies a distinct signature of circulating microRNAs in early radiographic knee osteoarthritis [PDF]

, 2020
OBJECTIVE: MicroRNAs act locally and systemically to impact osteoarthritis (OA) pathophysiology, but comprehensive profiling of the circulating miRNome in early vs late stages of OA has yet to be conducted.
Ali, Shabana A, Appleton, T, Bethune-Waddell, D, Espin-Garcia, O, Gandhi, R, Jurisica, I, Kapoor, M, Keshavarzi, S, Lively, S, Pastrello, C, Perruccio, A V, Potla, P, Rampersaud, Y R, Rockel, J S, Shestopaloff, K, Veillette, C   +15 more
core   +2 more sources

All‐Solution‐Processed Perovskite Light‐Emitting Transistors Enabled by a Fully Organic Architecture

Advanced Electronic Materials, EarlyView.
Fully solution‐processed light‐emitting transistors based on CsPbBr3 perovskite nanocrystals (Pe‐LETs) are demonstrated using an all‐organic platform. By optimizing film formation and device integration, the Pe‐LETs achieve bright green emission with excellent color purity and a peak external quantum efficiency of 4.17 × 10−3 %, marking a step forward ...
Kelment Zahoaliaj, Alice Fappani, Francesca Pallini, Valentina Bellotti, Nicolò Quaresima, Margherita Bolognesi, Mario Prosa, Luca Beverina, Stefano Toffanin   +8 more
wiley   +1 more source

Annual Report of the 2022 National Clinical Database: Decade‐Long Trends and Current Status of Gastroenterological Surgery in Japan

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim The National Clinical Database (NCD) of Japan is the largest nationwide registry, covering over 95% of surgeries in the country. This 2022 annual report summarizes the short‐term outcomes of gastroenterological surgeries and discusses trends and insights over the past decade.
Koshi Kumagai, Arata Takahashi, Hideki Ueno, Naoki Hiki, Yoshiki Kajiwara, Tomoki Ebata, Takao Otsuka, Taro Oshikiri, Yoshihiro Kakeji, Takanori Goi, Akio Saiura, Hiroshi Saeki, Chie Tanaka, Masanori Tokunaga, Tsutomu Fujii, Satoru Matsuda, Tsunekazu Mizushima, Hiroyuki Yamamoto, Yuko Kitagawa, Ken Shirabe   +19 more
wiley   +1 more source

Prognostic Significance of Portal Vein Tumor Thrombus in Pancreatic Ductal Adenocarcinoma Treated With Chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT ...
Aoi Hayasaki, Motonori Nagata, Miki Usui, Hiroshi Imai, Yusuke Iizawa, Akihiro Tanemura, Yasuhiro Murata, Naohisa Kuriyama, Masashi Kishiwada, Shugo Mizuno   +9 more
wiley   +1 more source

The role of PAQR3 in cancer progression – Molecular regulation, signaling pathways, and clinical implications: A review

Biomolecules & Biomedicine
Progesterone and adiponectin receptor 3 (PAQR3) is a Golgi-localized seven-transmembrane protein that anchors rapidly accelerated fibrosarcoma kinase (Raf) and suppresses rat sarcoma/rapidly accelerated fibrosarcoma/mitogen-activated protein kinase ...
Yan Lv, Dan Li, Xiao-Fei Ren, Qiang Guo, Qiao-Ya Ren   +4 more
doaj   +1 more source

Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma. [PDF]

Pseudoexfoliation glaucoma is a severe form of secondary open angle glaucoma and is associated with activation of the TGF-β pathway by TGF-β1. MicroRNAs (miRNAs) are small non-coding RNA species that are involved in regulation of mRNA expression and ...
Atkinson, SD, Callaghan, Breedge, Doyle, Chelsey, Henry, Megan, Lester, Karen, McKenna, Declan J, Roodnat, Anton, Sheridan, Carl M., Willoughby, Colin   +8 more
core   +2 more sources

Erosion of granular sediments by submerged impinging jets: Particle size effects and cohesion onset

AIChE Journal, EarlyView.
Abstract This study investigates the erosion behavior and modeling of glass particle beds under impinging jet conditions, with a focus on particle size effects and the onset of cohesion. Ultrasonic profiling is implemented to scan and measure static crater profiles.
Ahmad Mohamadiyeh, Jeffrey Peakall, Michael Fairweather, Martyn Barnes, Timothy N. Hunter   +4 more
wiley   +1 more source