Results 241 to 250 of about 319,034 (267)
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Molecular Biotechnology, 2023
Endometrial cancer (EC) is the most common gynecological tumor. Circular RNAs are a novel type of non-coding RNA that have important regulatory functions, particularly in the pathogenic progression of cancer. In this study, we investigated the function of circCCL22, and elucidated its molecular mechanism in EC progresssion. The expression of circCCL22,
Sichao Liu +4 more
semanticscholar +3 more sources
Endometrial cancer (EC) is the most common gynecological tumor. Circular RNAs are a novel type of non-coding RNA that have important regulatory functions, particularly in the pathogenic progression of cancer. In this study, we investigated the function of circCCL22, and elucidated its molecular mechanism in EC progresssion. The expression of circCCL22,
Sichao Liu +4 more
semanticscholar +3 more sources
Archives of Gynecology and Obstetrics, 2021
Dysregulation of long non-coding RNAs (lncRNAs) is being found to have relevance to human cancers, including breast cancer (BC). The aim of this study was to further explore the functional role and molecular mechanisms of small nucleolar RNA host gene 14 (SNHG14) on BC progression.The expression levels of SNHG14, miR-543, and krüppel-like factor 7 ...
Daoping Zhang, X-M Ding, M. Peng
semanticscholar +3 more sources
Dysregulation of long non-coding RNAs (lncRNAs) is being found to have relevance to human cancers, including breast cancer (BC). The aim of this study was to further explore the functional role and molecular mechanisms of small nucleolar RNA host gene 14 (SNHG14) on BC progression.The expression levels of SNHG14, miR-543, and krüppel-like factor 7 ...
Daoping Zhang, X-M Ding, M. Peng
semanticscholar +3 more sources
miR-543 inhibites cervical cancer growth and metastasis by targeting TRPM7.
Chemico-Biological Interactions, 2019Dysregulation of miR-543 has been implicated to play crucial roles in various human cancers. However, the function of miR-543 involved in cervical cancer (CC) progress remains largely unknown.
Xiaoying Liu, Lu Gan, Jing Zhang
semanticscholar +3 more sources
LncRNA NEAT1 regulates chondrocyte proliferation and apoptosis via targeting miR-543/PLA2G4A axis
Human Cell, 2020Osteoarthritis (OA), which is characterized by articular cartilage degeneration, shows a gradually increasing incidence with age. This study explored the molecular mechanism underlying the proliferation and apoptosis of chondrocytes during OA progression. In this study, chondrocytes were isolated from human knee cartilages.
Peng Xiao +6 more
semanticscholar +3 more sources
Anti-Cancer Drugs, 2022
Background Circular RNAs can act as critical regulators in the tumorigenesis and chemoresistance of ovarian cancer (OC). Herein, this work aimed to probe the function and mechanism of circ_0026123 in the cisplatin (DDP) resistance and progression of OC ...
Lei Wei, Wei He, Hua Zhao, Pei Zhao
semanticscholar +3 more sources
Background Circular RNAs can act as critical regulators in the tumorigenesis and chemoresistance of ovarian cancer (OC). Herein, this work aimed to probe the function and mechanism of circ_0026123 in the cisplatin (DDP) resistance and progression of OC ...
Lei Wei, Wei He, Hua Zhao, Pei Zhao
semanticscholar +3 more sources
International Journal of Developmental Neuroscience
Human umbilical cord mesenchymal stem cells (hUC‐MSCs) have the ability to differentiate into nerve cells, which offers promising options for treating neurodegenerative diseases.
D. An, Yangfan Wang, Xin Wang
semanticscholar +3 more sources
Human umbilical cord mesenchymal stem cells (hUC‐MSCs) have the ability to differentiate into nerve cells, which offers promising options for treating neurodegenerative diseases.
D. An, Yangfan Wang, Xin Wang
semanticscholar +3 more sources
Cancer Biotherapy and Radiopharmaceuticals, 2020
Background: Long noncoding RNA SNHG10 has been reported to promote the development of liver cancer. While by analyzing The Cancer Genome Atlas (TCGA) dataset we observed the downregulation of SNHG10 in non-small cell lung cancer (NSCLC). This study aimed
Zhe Zhang +6 more
semanticscholar +3 more sources
Background: Long noncoding RNA SNHG10 has been reported to promote the development of liver cancer. While by analyzing The Cancer Genome Atlas (TCGA) dataset we observed the downregulation of SNHG10 in non-small cell lung cancer (NSCLC). This study aimed
Zhe Zhang +6 more
semanticscholar +3 more sources
Regulatory Mechanism of miR-543-3p on GLT-1 in a Mouse Model of Parkinson's Disease.
ACS Chemical Neuroscience, 2019Parkinson's disease (PD) features the degeneration and death of dopamine neurons in the substantia nigra pars compacta and the formation of Lewy bodies that contain α-synuclein. Among the numerous PD etiologies, glutamate excitotoxicity is a research hot
Xiaojuan Wu +9 more
semanticscholar +3 more sources
The role of miR‐543 in human cancerous and noncancerous diseases
Journal of Cellular Physiology, 2020AbstractMicroRNA (miRNA) is a noncoding single‐stranded RNA molecule that can regulate the posttranscriptional expression level of a gene by binding to the 3′‐untranslated region (3′‐UTR) of the target messenger RNA. miR‐543 is a kind of miRNA, which plays an important role in the occurrence and development of various human cancerous and noncancerous ...
Cong Zhou, Xin Zhao, Shiwei Duan
openaire +2 more sources
Molecular and Cellular Endocrinology, 2023
BACKGROUND Myocardial interstitial fibrosis is an important manifestation of diabetic heart disease, and insulin resistance is one of the mechanisms of myocardial interstitial fibrosis.
Y. Tan +8 more
semanticscholar +1 more source
BACKGROUND Myocardial interstitial fibrosis is an important manifestation of diabetic heart disease, and insulin resistance is one of the mechanisms of myocardial interstitial fibrosis.
Y. Tan +8 more
semanticscholar +1 more source