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MiR‐543 regulates myoblast proliferation and differentiation of C2C12 cells by targeting KLF6

Journal of Cellular Biochemistry, 2020
AbstractMicroRNA‐543 (miR‐543) has been found to play a suppressive role in various human cancers in many studies, whereas the specific functions of miR‐543 in muscle development remain poorly understood. Here, we found that the expression of miR‐543 was high in skeletal muscle and increased during the differentiation of C2C12 cells.
Tingting Kang   +8 more
openaire   +2 more sources

Ceruloplasmin inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells and is negatively regulated by miR-543

Nucleosides, Nucleotides & Nucleic Acids, 2022
Ceruloplasmin (CP), recognized as a member of multicopper oxidase family, is related to the progression of diverse cancers in human beings. This study is designed to clarify the expression characteristics, biological function and related mechanism of CP in nasopharyngeal carcinoma (NPC).CP expression in NPC tissues and cells was probed by quantitative ...
Hang, Yang   +6 more
openaire   +2 more sources

LINC01082 Inhibits Non-Small Cell Lung Cancer by Targeting the miR-543/TNRC6A Axis

Biochemical Genetics, 2023
Non-small cell lung cancer (NSCLC) accounts for over 80% of lung cancer cases and have poor clinical outcomes. Increasing number of lncRNAs are reported to be implicated in the carcinogenesis of NSCLC. Previous lncRNA-seq results showed that LINC01082 was under-expressed in several cancer types. In the current study, we focused on the role of LINC01082
Ran, Yang, Jinli, Han, Song, Zhao
openaire   +2 more sources

CircCCL22 Regulates CDC25A via Sponging miR-543 and Promotes Proliferation and Metastasis in Endometrial Cancer

Molecular Biotechnology, 2023
Endometrial cancer (EC) is the most common gynecological tumor. Circular RNAs are a novel type of non-coding RNA that have important regulatory functions, particularly in the pathogenic progression of cancer. In this study, we investigated the function of circCCL22, and elucidated its molecular mechanism in EC progresssion. The expression of circCCL22,
Sichao Liu   +4 more
openaire   +2 more sources

MiR-543 Regulates the Development of Chronic Obstructive Pulmonary Disease by Targeting Interleukin-33

Clinical Laboratory, 2018
This main aim of the study was to evaluate the expression and specific role of miR-543 in the progression of chronic obstructive pulmonary disease (COPD), thereby evaluating their diagnostic ability and treatment in COPD patients.Real time PCR was carried out to explore the level of miR-543 in the plasma and lung tissues of COPD patients and controls ...
Huozhen, He   +3 more
openaire   +2 more sources

LncRNA-LINC01089 inhibits lung adenocarcinoma cell proliferation and promotes apoptosis via sponging miR-543

Tissue and Cell, 2021
LINC01089, a newly discovered long non-coding RNA (lncRNA), has been reported to inhibit the progression of various types of cancers. This study aimed to characterize LINC01089 in the pathogenesis of lung adenocarcinoma (LUAD). LINC01089 expression in LUAD tissues or/and cells and its association with the overall survival of LUAD patients was analyzed ...
Youwen, Xu   +5 more
openaire   +2 more sources

LEF1-AS1 is implicated in the malignant development of glioblastoma via sponging miR-543 to upregulate EN2

Brain Research, 2020
Glioblastoma (GBM) has been regarded as the most aggressive disease in the nervous system. Accumulating literatures have illustrated the crucial role of competing endogenous RNAs (ceRNAs) network in the pathogenesis and progression of various tumors. The promoting effect of LEF1-AS1 on GBM development has been previously identified.
Shi, Zeng   +6 more
openaire   +2 more sources

Hsa_circ_0092355 Accelerates Papillary Thyroid Cancer Progression by Regulating the miR-543/PDE5A Pathway

Hormone and Metabolic Research
AbstractCircRNAs have been found to participate in the progression of various tumors. In the present study, we aimed to clarify the role of hsa_circ_0092355 in papillary thyroid cancer (PTC) cell development. RT-qPCR was used to determine the expression of hsa_circ_0092355, miR-543, and PDE5A.
Zhijun, Sun   +3 more
openaire   +2 more sources

MiR‐543 regulates myoblast proliferation and differentiation of C2C12 cells by targeting KLF6

Journal of Cellular Biochemistry, 2020
Tingting Kang, Yu Xi, Mengsi Zhan
exaly  

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