Results 251 to 260 of about 319,034 (267)

LncRNA SNHG6 promotes LMO3 expression by sponging miR-543 in glioma

Molecular and Cellular Biochemistry, 2020
Small nucleolar RNA host gene 6 (SNHG6) was a newly discovered long non-coding RNA, which was involved in the occurrence and development of a variety of cancers and was on the rise in human cancers. However, the molecular mechanism of SNHG6 in glioma required further investigation.
Yin Zhang, Jiayin An, Yuchun Pei
openaire   +2 more sources

MiR-543 functions as tumor suppressor in ovarian cancer by targeting TWIST1.

JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2020
MicroRNAs (miRNAs) have been demonstrated to have promoting or inhibiting effects on the tumorigenesis of multiple cancers, including ovarian cancer (OC), by regulating its downstream target genes. In the presented experiment, our aim was to explore the role of miR-543 in OC cell proliferation and invasion. Results of quantitative reverse transcription-
Q, Yu, Z, Zhang, B, He, H, Wang, P, Shi, Y, Li   +5 more
openaire   +3 more sources

LncRNA-LINC01089 inhibits lung adenocarcinoma cell proliferation and promotes apoptosis via sponging miR-543

Tissue and Cell, 2021
LINC01089, a newly discovered long non-coding RNA (lncRNA), has been reported to inhibit the progression of various types of cancers. This study aimed to characterize LINC01089 in the pathogenesis of lung adenocarcinoma (LUAD). LINC01089 expression in LUAD tissues or/and cells and its association with the overall survival of LUAD patients was analyzed ...
Youwen, Xu, Ling, Lin, Dongqing, Lv, Shuangquan, Yan, Susu, He, Hongfei, Ge   +5 more
openaire   +2 more sources

Exosomal miR-543 derived from umbilical cord mesenchymal stem cells ameliorates endometrial fibrosis in intrauterine adhesion via downregulating N-cadherin.

Placenta, 2022
INTRODUCTION Human umbilical cord mesenchymal stem cells (UCMSCs) play an important role in repairing the damaged endometrium of intrauterine adhesion (IUA).
Dong-lan Yuan, Ting Guo, Hua Qian, Chunyan Jin, Hongshan Ge, YinLing Zhao, Dandan Zhu, Mei Lin, Hua Wang, Hong Yu   +9 more
semanticscholar   +1 more source

miR-543 promotes gastric cancer cell proliferation by targeting SIRT1

Biochemical and Biophysical Research Communications, 2016
SIRT1, a class III histone deacetylase, exerts inhibitory effects on tumorigenesis and is downregulated in gastric cancer. However, the role of microRNAs in the regulation of SIRT1 in gastric cancer is still largely unknown. Here, we identified miR-543 as a predicted upstream regulator of SIRT1 using 3 different bioinformatics databases.
Juan, Li, Guoying, Dong, Bo, Wang, Wei, Gao, Qing, Yang   +4 more
openaire   +2 more sources

Ceruloplasmin inhibits the proliferation, migration and invasion of nasopharyngeal carcinoma cells and is negatively regulated by miR-543

Nucleosides, Nucleotides & Nucleic Acids, 2022
Background Ceruloplasmin (CP), recognized as a member of multicopper oxidase family, is related to the progression of diverse cancers in human beings.
Hang Yang, Y. Bao, F. Jin, Chong Jiang, Zhaoguang Wei, Zhenli Liu, Yaping Xu   +6 more
semanticscholar   +1 more source

Down-regulation of the miR-543 alleviates insulin resistance through targeting the SIRT1

Biochemical and Biophysical Research Communications, 2015
Insulin resistance plays an important role in the development of hypertension, which is seriously detrimental to human health. Recently, Sirtuin-1 (SIRT1) has been found to participate in regulation of insulin resistance. Therefore, further studies focused on the SIRT1 regulators might provide a potential approach for combating insulin resistance and ...
Xiaojing, Hu, Liyi, Chi, Wentao, Zhang, Tiao, Bai, Wei, Zhao, Zhanbin, Feng, Hongyan, Tian   +6 more
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MiR‐543 regulates myoblast proliferation and differentiation of C2C12 cells by targeting KLF6

Journal of Cellular Biochemistry, 2020
AbstractMicroRNA‐543 (miR‐543) has been found to play a suppressive role in various human cancers in many studies, whereas the specific functions of miR‐543 in muscle development remain poorly understood. Here, we found that the expression of miR‐543 was high in skeletal muscle and increased during the differentiation of C2C12 cells.
Tingting Kang, Wenkai Xing, Yu Xi, Kun Chen, Mengsi Zhan, Xiaoyin Tang, Yueying Wang, Ruirui Zhang, Minggang Lei   +8 more
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Matrine regulates miR‐495‐3p/miR‐543/PDK1 axis to repress the progression of acute myeloid leukemia via the Wnt/β‐catenin pathway

Chemical Biology and Drug Design
Acute myeloid leukemia (AML) is a commonly hematological malignancy with feature of rapidly increased immature myeloid cells in bone marrow. The anti‐tumor activity of matrine has been reported in various cancers.
Yanping Lei, Xiao Li, Liping Zhu
semanticscholar   +1 more source

Study on the regulation of trophoblast activity by abnormally expressed hsa_circ_0024838/miR-543/HIF1A in patients with gestational diabetes mellitus.

Placenta
INTRODUCTION This study aimed to screen circRNAs involved in gestational diabetes mellitus (GDM)-related macrosomia. One differentially expressed circRNA (DEC), hsa_circ_0024838, was further tested for its potential role and mechanism in trophoblasts ...
Qian Liu, Juan Gui, Lianzhi Wu
semanticscholar   +1 more source