MiR-544 promotes immune escape through downregulation of NCR1/NKp46 via targeting RUNX3 in liver cancer [PDF]
Cancer Cell International, 2018 Objective To study the potential role of miR-544 in the immune escape mechanism of hepatoma cells. Methods Natural killer (NK) cells were collected from healthy volunteers and patients with liver cancer.
Chenwei Pan +8 more
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Lack of miR-379/miR-544 Cluster Resists High-Fat Diet-Induced Obesity and Prevents Hepatic Triglyceride Accumulation in Mice [PDF]
Frontiers in Cell and Developmental Biology, 2021 Non-alcoholic fatty liver disease (NAFLD) affects obesity-associated metabolic syndrome, which exhibits hepatic steatosis, insulin insensitivity and glucose intolerance.
Congcong Cao +8 more
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miR-544 promotes maturity and antioxidation of stem cell-derived endothelial like cells by regulating the YY1/TET2 signalling axis [PDF]
Cell Communication and Signaling, 2020 Background Inflammation and oxidative stress induced by oxidized low density lipoprotein are the main causes of vascular endothelial injury and atherosclerosis. Endothelial cells are important for the formation and repair of blood vessels.
Jianming Guo +5 more
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circMIRIAF aggravates myocardial ischemia-reperfusion injury via targeting miR-544/WDR12 axis [PDF]
Redox BiologyExploring and discovering novel circRNAs is one of the ways to develop innovative drugs for the diagnosis and treatment of myocardial ischemia-reperfusion injury (MI/RI). In the work, some dysregulated circRNAs were found by microarray screening analysis
Lianhong Yin +5 more
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LncRNA GAS5 enhanced the killing effect of NK cell on liver cancer through regulating miR-544/RUNX3 [PDF]
Innate Immunity, 2019 This study aimed to explore the role of lncRNA GAS5 in the regulation of the killing effect of NK cells on liver cancer. Compared with a control group, lncRNA GAS5, RUNX3, and NCR1 were down-regulated in NK cells of patients with liver cancer, whereas ...
Peipei Fang +10 more
doaj +5 more sources
CircRNA Cdyl promotes the proliferation and differentiation of neural stem cells via regulating miR-544-3p/Nr3c1 axis [PDF]
iScienceSummary: Emerging evidence suggests that numerous circular RNAs (circRNAs) are abnormally expressed during neural stem cell (NSC) differentiation, which may play an important role in the fate of NSCs.
Wen Li +11 more
doaj +5 more sources
Genetic Polymorphisms of miR-146a and miR-155 in Psoriasis and Psoriatic Arthritis: Evidence from a Turkish Case-Control Study [PDF]
Dermatology Practical & ConceptualIntroduction: Psoriasis, a widespread inflammatory cutaneous disease, is driven by an interplay of genetic and environmental risk factors. miR-155 and miR-146a have been implicated in the regulation of inflammatory pathways. Objectives: In the current
Fadime Mutlu İçduygu +5 more
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Integration of mRNA and MiRNA analysis reveals the molecular mechanisms of testicular development in newborn and adult sheep [PDF]
BMC GenomicsFecundity limits sheep industry development, but crossbreeding can help. Yet, mechanisms of testis development in Southdown × Hu F1, especially differential mechanisms at key stages, are rarely studied.
Binpeng Xi +6 more
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The Book “History of Spain” Is an Important Event for Hispanists
Ибероамериканские тетради, 2023 Book review: History of Spain / Translation from Spanish: V.A. Vedyushkin, G.A. Popova, E.E. Yurchik.
N. E. Anikeeva
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Frontiers in Veterinary Science, 2022 In seasonal estrus, it is well known that melatonin-regulated biorhythm plays a key role. Some studies indicate that the adrenal gland plays an important role in reproduction in mammals, but the molecular mechanism is not clear.
Xiaolong Du +5 more
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