Long noncoding RNA LINC01615 promotes keloid development via sponging miR-590-3p to regulate FGF2 expression [PDF]
, 2020 Abstract Background A keloid is a benign human skin tumor that resulted by fibrous overgrowths during wound healing. Long noncoding RNAs (lncRNAs) are indicated to involve in the development of keloid. However, the role of lncRNA LINC01615 in regulating keloid development and the underlying mechanism are still unknown.
Chen Wanying +7 more
openaire +2 more sources
Frontiers in Physiology, 2019 Atrial stretch and dilatation are common features of many clinical conditions predisposing to atrial fibrillation (AF). MicroRNAs (miRs) are emerging as potential molecular determinants of AF, but their relationship with atrial dilatation (AD) is poorly ...
Michela Masè +9 more
doaj +1 more source
Advanced Healthcare Materials, Volume 14, Issue 18, July 15, 2025.Hybrid NPs are developed as efficient, scalable nanocarriers for in vitro microRNA delivery, ensuring high loading efficiency, controlled release, physiological and long‐term storage stability. They outperform commercial lipid‐based reagents in terms of transfection efficiency and biocompatibility.
Letizia Nicoletti +11 more
wiley +1 more source
A multidimensional integration analysis reveals potential bridging targets in the process of colorectal cancer liver metastasis. [PDF]
PLoS ONE, 2017 Approximately 9% of cancer-related deaths are caused by colorectal cancer. Liver metastasis is a major factor for the high colorectal cancer mortality rate.
Bo Gao +10 more
doaj +1 more source
Expression and function of small RNAs in normal and psoriatic skin [PDF]
, 2012 Psoriasis is a chronic, inflammatory skin disease characterized by hyperproliferation and altered differentiation of keratinocytes, and infiltration of activated immune cells in the epidermis.
Joyce, Cailin
core +1 more source
The Quest for New Approaches in Myocarditis and Inflammatory Cardiomyopathy [PDF]
, 2016 Myocarditis is a diverse group of heart-specific immune processes classified by clinical and histopathological manifestations. Up to 40% of dilated cardiomyopathy is associated with inflammation or viral infection.
Cooper, Leslie T. +3 more
core +1 more source
Decoding the pancreatic cancer microenvironment: The multifaceted regulation of microRNAs
Clinical and Translational Medicine, Volume 15, Issue 7, July 2025.miRNAs play multiple roles in the tumour microenvironment of pancreatic cancer, including angiogenesis, interactions with cancer‐associated fibroblasts, the immune microenvironment, exosome communication, the neural microenvironment and metabolic reprogramming.
Jie Ji +9 more
wiley +1 more source
Melatonin: A Potential Therapy for Osteoporosis With Insights Into Molecular Mechanisms
Journal of Pineal Research, Volume 77, Issue 4, July 2025.ABSTRACT Melatonin is a versatile neurohormone with diverse molecular functions, including sleep regulation, inflammation reduction, antioxidant activity, immune modulation, and anticancer properties. In bone metabolism, it promotes osteoblast formation, inhibits osteoclast activity, and synchronizes skeletal tissue rhythms to support bone health.
Ko‐Hsiu Lu +4 more
wiley +1 more source
MiR‐590‐3p Restores Autophagy in Cultured Human Glomerular Endothelial Cells Exposed to High Glucose
The FASEB Journal, 2019 BackgroundAutophagy is an important mechanism for homeostasis. Previous data mining indicated that miR‐590‐3p was involved in diabetes‐induced endothelial dysfunction. The present study was designed to investigate the role of microRNA‐590‐3p (miR‐590‐3p) in the regulation of autophagy in cultured endothelial cells incubated with high glucose ...
Wenjie Liu, Yi Shi
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Figure S2 from miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2–Versican Pathway [PDF]
, 2023 Mohamed E. Salem +11 more
openalex +2 more sources