Results 121 to 130 of about 4,814 (170)

Association between the Mediterranean diet and metabolic syndrome with serum levels of miRNA in morbid obesity [PDF]

open access: yes, 2021
Background: The Mediterranean diet (MD) could be involved in the regulation of different miRNAs related to metabolic syndrome (MS). Methods: We analyzed the serum level of mir-let7a-5p, mir-21, mir-590, mir-107 and mir-192 in patients with morbid ...
Domínguez-Bendala, J.   +6 more
core  

miR-590-3pInhibits Pyroptosis in Diabetic Retinopathy by TargetingNLRP1and Inactivating the NOX4 Signaling Pathway

open access: yesInvestigative Opthalmology & Visual Science, 2019
To elucidate the mechanism whereby miR-590-3p regulates pyroptosis in diabetic retinopathy (DR).Human retinal microvascular endothelial cells (HRMECs) incubated with high glucose (HG) were used to establish cell models, and the expression levels of miR-590-3p, caspase-1, IL-1β, NLRP1, NOX4, TXNIP, NLRP3, and ROS were determined.
Chufeng, Gu   +8 more
openaire   +2 more sources

Comprehensive molecular characterization of the hippo signaling pathway in cancer [PDF]

open access: yes, 2018
Hippo signaling has been recognized as a key tumor suppressor pathway. Here, we perform a comprehensive molecular characterization of 19 Hippo core genes in 9,125 tumor samples across 33 cancer types using multidimensional “omic” data from The Cancer ...
Abdel-Rahman, MH   +746 more
core   +4 more sources

The clinical significance of miR-590-3p in acute myeloid leukemia and potential regulatory mechanism based on bioinformatic prediction

open access: yesTürk Biyokimya Dergisi
Acute myeloid leukaemia (AML) usually has a poor prognosis, and an effective prognostic marker is needed. MicroRNAs (miRNAs) have potential as prognostic markers. Therefore, the prognostic diagnostic role and potential regulatory mechanisms of miR-590-3p
Ma Li   +4 more
doaj   +1 more source

Analysis of the dynamic co-expression network of heart regeneration in the zebrafish. [PDF]

open access: yes, 2016
The zebrafish has the capacity to regenerate its heart after severe injury. While the function of a few genes during this process has been studied, we are far from fully understanding how genes interact to coordinate heart regeneration.
Androsova, G.   +17 more
core   +8 more sources

A Pilot Study Investigating the Impact of High Altitude on Myostatin and Irisin Levels [PDF]

open access: yes
Many people visit and stay at high altitude due to adventure or occupation. The high-altitude environment comprises many factors alien to sea residents and detrimental to physical and mental health.
Rathor, Richa   +2 more
core   +2 more sources

The Practical Landscape of Cytokine‐Targeted miRNAs to Enhance NK Cell Function in Cancer Immunotherapy: A Bioinformatic Analysis

open access: yesCancer Reports
Introduction Suppression within the tumor microenvironment (TME) hampered natural killer (NK) cells and their role in cancer immunotherapy. This study explores how interleukin (IL) signaling (IL‐12A, IL‐12B, IL‐15, IL‐18) and interferon gamma (IFNG or ...
Arefeh Zabeti Touchaei   +2 more
doaj   +1 more source

Design of bioinformatic tools for integrative analysis of microRNA-mRNA interactome applied to digestive cancers [PDF]

open access: yes, 2017
[spa] En esta tesis se han desarrollado e implementado distintas herramientas bioinformáticas que permiten el estudio de las interacciones miRNA-mRNA en contextos celulares específicos.
Vila Casadesús, Maria
core   +2 more sources

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