Results 101 to 110 of about 285,099 (189)
miR-140-3p suppresses the proliferation and migration of macrophages
, 2022 Macrophages benefit myelin debris removal, blood vessel formation, and Schwann cell activation following peripheral nerve injury. Identifying factors that modulate macrophage phenotype may advantage the repair and regeneration of injured peripheral ...
Pingping Qiao (12881638) +6 more
core +1 more source
International Journal of Biological MacromoleculesSepsis is a fatal syndrome characterized by uncontrolled systemic inflammatory responses. Circular RNAs (circRNAs) are involved in the modulation of various pathophysiological processes, but their potential role in sepsis has largely been unexplored. In this study, we observed differential expression of circMLH3 between healthy volunteers and septic ...
Qin, Sun +8 more
openaire +2 more sources
, 2021 Abstract Background Ovarian cancer (OC) remains a common gynecologic malignancy. Tumor-derived extracellular vesicles (EVs) contribute to pro-metastasis microenvironment by carrying microRNAs (miRs). This study investigated the mechanism of miR-590-3p carried by OC cell-derived EVs in OC metastasis. Methods miR-590-3p expression in OC tissues
Yunyun Zheng, Kang Zhu, Guihu Wang
openaire +1 more source
Expression Levels of miR-590-3p in Hepatocellular Carcinoma and Osteosarcoma Cell Lines and its Downstream Target Genes [PDF]
, 2020 Small non-coding RNA (miRNA) sequences of around 18-25 nucleotides can regulate different cellular pathways by acting on tumor suppressors, oncogenes or both.
Elfar, Mennatallah Mohamed Bassem Mahmoud
core
Temozolomide resistance in glioblastoma: a non-coding RNA viewpoint
Advances in Cancer Biology - MetastasisAs an imidazotetrazine derived from the alkylating substance dacarbazine, Temozolomide (TMZ) is commonly used as the routine chemotherapy for new cases of glioblastoma multiforme (GBM). It substantially improves the clinical outcome of patients.
Maryam Motallebinezhad +6 more
doaj +1 more source
Investigative Opthalmology & Visual Science, 2019 To elucidate the mechanism whereby miR-590-3p regulates pyroptosis in diabetic retinopathy (DR).Human retinal microvascular endothelial cells (HRMECs) incubated with high glucose (HG) were used to establish cell models, and the expression levels of miR-590-3p, caspase-1, IL-1β, NLRP1, NOX4, TXNIP, NLRP3, and ROS were determined.
Chufeng, Gu +8 more
openaire +2 more sources
Hsa-miR-137, hsa-miR-520e and hsa-miR-590-3p perform crucial roles in Lynch syndrome
Oncology Letters, 2016 The aim of the present study was to identify the differentially expressed microRNAs (DEMs) between Lynch syndrome (LS) and the normal colonic (N-C) control samples, predict the target genes (TGs) and analyze the potential functions of the DEMs and TGs.
Changyu, Zhou +7 more
openaire +3 more sources
OncoTargets and therapy, 2020 In East Asia, hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancer types. Long noncoding RNA (lncRNA) prostate androgen-regulated transcript 1 (PART1) was reported to play crucial roles in regulating cancer progression. However, roles and mechanisms of action of PART1 in hepatocellular carcinoma (HCC) still remain unknown ...
Pu,Jian +8 more
openaire +3 more sources
HOXC-AS1-MYC regulatory loop contributes to the growth and metastasis in gastric cancer
Journal of Experimental & Clinical Cancer Research, 2019 Background Gastric cancer (GC) is one of the most prevalent and deadly malignancies worldwide. Accumulating reports have indicated the participation of long non-coding RNAs (lncRNAs) in the onset and progression of GC. Methods GSE109476 data was utilized
Yangyang Dong +6 more
doaj +1 more source
Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source