Results 111 to 120 of about 4,814 (170)

Expression and function of small RNAs in normal and psoriatic skin [PDF]

, 2012
Psoriasis is a chronic, inflammatory skin disease characterized by hyperproliferation and altered differentiation of keratinocytes, and infiltration of activated immune cells in the epidermis.
Joyce, Cailin
core   +1 more source

CircMLH3 induces mononuclear macrophage pyroptosis in sepsis by sponging miR-590-3p to regulate TAK1 expression

International Journal of Biological Macromolecules
Sepsis is a fatal syndrome characterized by uncontrolled systemic inflammatory responses. Circular RNAs (circRNAs) are involved in the modulation of various pathophysiological processes, but their potential role in sepsis has largely been unexplored. In this study, we observed differential expression of circMLH3 between healthy volunteers and septic ...
Qin, Sun, Zihan, Hu, Wei, Huang, Xu, Liu, Xiao, Wu, Wei, Chang, Ying, Tang, Fei, Peng, Yi, Yang   +8 more
openaire   +2 more sources

Immune non‐response despite effective antiretroviral therapy in people living with HIV: A review of potential mechanisms, biomarkers and therapeutic approaches

HIV Medicine, Volume 27, Issue 4, Page 498-512, April 2026.
Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre, Antoine Gross, Alain Makinson   +2 more
wiley   +1 more source

The Influence of Annealing on the Sb Layer in the Synthesis of [001]‐Oriented Sb2Se3 Film for Photoelectrochemical Hydrogen Gas Generation

Advanced Functional Materials, Volume 36, Issue 21, 12 March 2026.
[001]‐oriented Sb2Se3 film with improved crystallinity and adjusted composition is achieved via a new thermal treatment approach consisting of preliminary annealing of the Sb layer before its selenization. The findings of this work demonstrate enhanced charge carriers' transportation, a stable performance, and an improvement of H2 generation from ...
Magno B. Costa, Moisés A. de Araújo, Joaquim Puigdollers, Pablo Ortega, Teresa Andreu, Cristobal Voz, Edgardo Saucedo, Lucia H. Mascaro   +7 more
wiley   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

Advanced Materials, Volume 38, Issue 13, 3 March 2026.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko, Ian Gimino, Aastha Chandiwala, Bayan Alkotoub, Ali Bashiri Dezfouli, Heiko Reith, Asjad Bakhtiar, Rojda Hicsanmaz, Johann Brenner, Christoph J. O. Kaiser, Elena Belli, Shilpi Pandey, Samuel D. Rabkin, Kornelius Nielsch, Gabriele Multhoff, Oliver Hayden, Morteza Hasanzadeh Kafshgari   +16 more
wiley   +1 more source

Data from miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2–Versican Pathway

, 2023
<div>Abstract<p>miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this study, we determined the expression and function of miR-590-3p in EOC.
Chun Peng, Sergey N. Krylov, Burton B. Yang, Basel Refky, Barbara C. Vanderhyden, Asma Amleh, Jelena Brkić, Gang Ye, Heba Shawer, Stefanie Bernaudo, Jacob A. O'Brien, Mohamed Salem   +11 more
openaire   +1 more source

Temozolomide resistance in glioblastoma: a non-coding RNA viewpoint

Advances in Cancer Biology - Metastasis
As an imidazotetrazine derived from the alkylating substance dacarbazine, Temozolomide (TMZ) is commonly used as the routine chemotherapy for new cases of glioblastoma multiforme (GBM). It substantially improves the clinical outcome of patients.
Maryam Motallebinezhad, Ali Faravash, Mohammad Ghasemian, Zahra Tajik, Mohsen Ahmadi, Solat Eslami, Soudeh Ghafouri-Fard   +6 more
doaj   +1 more source

Computational Investigation of Regulatory Region SNPs of Autophagy Gene BECN1 [PDF]

The autophagy process plays a cytoprotective role and ensures the healthy survival of a cell. The role of autophagy has been implicated in various diseases, making it an essential candidate for therapeutic interventions.
Changotra, Harish, Kaur, Sargeet, Vashistt, Jitendraa   +2 more
core   +2 more sources

HOXC-AS1-MYC regulatory loop contributes to the growth and metastasis in gastric cancer

Journal of Experimental & Clinical Cancer Research, 2019
Background Gastric cancer (GC) is one of the most prevalent and deadly malignancies worldwide. Accumulating reports have indicated the participation of long non-coding RNAs (lncRNAs) in the onset and progression of GC. Methods GSE109476 data was utilized
Yangyang Dong, Xinyu Li, Zhibin Lin, Wenbing Zou, Yan Liu, Huiyang Qian, Jing Jia   +6 more
doaj   +1 more source

Development of the Clinical Application of miRNA with Proregenerative Effect on the Heart [PDF]

, 2018
Rationale: Cardiovascular disorders are the first cause of mortality and morbidity worldwide. This is due, at least in part, to the poor regenerative capacity of the heart and the lack of drugs able to foster cardiac regeneration.
Prosdocimo, Giulia
core   +1 more source