Results 131 to 140 of about 4,615 (182)

Additional file 1 of Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

, 2023
Additional file 1: Figure S1. miR-590-3p directly targets EMT-TF SLUG, ZEB1, and ZEB2 in HCC, as determined by bioinformatics analysis (A) CSmiRTar database analysis showing SLUG, ZEB1 and ZEB2 as miR-590-3p potential target genes. (B) TargetScan analysis showing the sequence alignment between the seed region of miR-50-3p and its downstream target ...
Youssef, Alaa Ibrahem, Khaled, Gehad Mahmoud, Amleh, Asma   +2 more
openaire   +1 more source

miR-590-3p attenuates atherosclerosis by preventing TNF-α-induced proliferation and migration of VSMCs via NF-κB pathway [PDF]

, 2023
Ren Guo, Heng Yang, Yuanyuan Xiang, Fangqin Nie, Sai Wang, Xin Yan, Yangxia Fu, Xiangdong Peng, Ruifang Chen   +8 more
openalex   +1 more source

Light‐Emitting Diodes Based on Metal Halide Perovskite and Perovskite Related Nanocrystals

Advanced Materials, Volume 37, Issue 25, June 26, 2025.
The review covers the past and current developments in light‐emitting diodes (LEDs) exploiting nanocrystals of halide perovskites and perovskite‐related materials. The review examines the aspects of material optimizations, device engineering, and applications.
Ying Liu, Zhuangzhuang Ma, Jibin Zhang, Yanni He, Jinfei Dai, Xinjian Li, Zhifeng Shi, Liberato Manna   +7 more
wiley   +1 more source

Temozolomide resistance in glioblastoma: a non-coding RNA viewpoint

Advances in Cancer Biology - Metastasis
As an imidazotetrazine derived from the alkylating substance dacarbazine, Temozolomide (TMZ) is commonly used as the routine chemotherapy for new cases of glioblastoma multiforme (GBM). It substantially improves the clinical outcome of patients.
Maryam Motallebinezhad, Ali Faravash, Mohammad Ghasemian, Zahra Tajik, Mohsen Ahmadi, Solat Eslami, Soudeh Ghafouri-Fard   +6 more
doaj   +1 more source

A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts [PDF]

, 2016
AGING applies the Creative Commons Attribution License (CCAL) to all works we publishWe acknowledge the financial support of the University of Sheffield, The Pathological Society London, The University of Otago-Dunedin and the Development and Promotion ...
Abbadie, Benetti, Berger, Bernad, Campisi, Campisi, Campisi, Chen, Chen, Dubinett, Fan, Felley-Bosco, Ho, Ittmann, Joel, Joyce, Lamas, Lambert, Lefaix, Li, Liu, Lowe, McCance, Mi, Murdoch, Neel, Nelson, Ostrowski, Parkinson, Partridge, Pecot, Peters-Golden, Prime, Prime, Qiu, Reisfeld, Scully, Takeyama, Teng, Thorin, Toews, Vaheri, White, You   +43 more
core   +3 more sources

A Self‐Assembling LYTAC Mediates CTGF Degradation and Remodels Inflammatory Tumor Microenvironment for Triple‐Negative Breast Cancer Therapy

Advanced Science, Volume 12, Issue 23, June 20, 2025.
A CTGF‐LYTAC nanoplatform is developed to selectively degrade connective tissue growth factor (CTGF) in triple‐negative breast cancer (TNBC), inhibiting TGF‐β signaling and cell interactions in the tumor microenvironment (TME). This strategy effectively suppresses tumor growth and metastasis, outperforming antibody‐based therapy.
Jia‐Yi Lin, Ye Wu, Xiao‐Hui Liang, Min Tang, Xin Sun, Sheng‐Xin Lu, Jin‐Mei Jin, Xin Guo, Bei Wang, Hong‐Zhuan Chen, Wei‐Dong Zhang, Xin Luan   +11 more
wiley   +1 more source

Mechanisms of vascular smooth muscle contraction and the basis for pharmacologic treatment of smooth muscle disorders [PDF]

, 2016
The smooth muscle cell directly drives the contraction of the vascular wall and hence regulates the size of the blood vessel lumen. We review here the current understanding of the molecular mechanisms by which agonists, therapeutics, and diseases ...
Aggarwal, M., Brozovich, F. V., Degen, C. V., Gao, Yuan Z., Morgan, K. G., Nicholson, C. J.   +5 more
core   +1 more source

Additional file 3 of Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

, 2023
Additional file 3: Figure (S3). MDM2 siRNA effectively silences MDM2 expression at the protein levels. Western blot uncropped full-length blot for A) first biological replicate and B) second biological replicate.
Youssef, Alaa Ibrahem, Khaled, Gehad Mahmoud, Amleh, Asma   +2 more
openaire   +1 more source

HOXC-AS1-MYC regulatory loop contributes to the growth and metastasis in gastric cancer

Journal of Experimental & Clinical Cancer Research, 2019
Background Gastric cancer (GC) is one of the most prevalent and deadly malignancies worldwide. Accumulating reports have indicated the participation of long non-coding RNAs (lncRNAs) in the onset and progression of GC. Methods GSE109476 data was utilized
Yangyang Dong, Xinyu Li, Zhibin Lin, Wenbing Zou, Yan Liu, Huiyang Qian, Jing Jia   +6 more
doaj   +1 more source

Computational Investigation of Regulatory Region SNPs of Autophagy Gene BECN1 [PDF]

The autophagy process plays a cytoprotective role and ensures the healthy survival of a cell. The role of autophagy has been implicated in various diseases, making it an essential candidate for therapeutic interventions.
Changotra, Harish, Kaur, Sargeet, Vashistt, Jitendraa   +2 more
core   +2 more sources