Association between the Mediterranean diet and metabolic syndrome with serum levels of miRNA in morbid obesity [PDF]
Background: The Mediterranean diet (MD) could be involved in the regulation of different miRNAs related to metabolic syndrome (MS). Methods: We analyzed the serum level of mir-let7a-5p, mir-21, mir-590, mir-107 and mir-192 in patients with morbid ...
Domínguez-Bendala, J.+6 more
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<div>Abstract<p>miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this study, we determined the expression and function of miR-590-3p in EOC.
Chun Peng+11 more
openaire +1 more source
A Pilot Study Investigating the Impact of High Altitude on Myostatin and Irisin Levels [PDF]
Many people visit and stay at high altitude due to adventure or occupation. The high-altitude environment comprises many factors alien to sea residents and detrimental to physical and mental health.
Rathor, Richa+2 more
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Sepsis is a fatal syndrome characterized by uncontrolled systemic inflammatory responses. Circular RNAs (circRNAs) are involved in the modulation of various pathophysiological processes, but their potential role in sepsis has largely been unexplored. In this study, we observed differential expression of circMLH3 between healthy volunteers and septic ...
Qin, Sun+8 more
openaire +2 more sources
Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea [PDF]
Background Dysregulated expression of microRNAs (miRNAs) has been previously observed in human cancer tissues and shown promise in defining tumor status.
A Krek+70 more
core +3 more sources
Metformin-induced metabolic reprogramming of chemoresistant ALDHbright breast cancer cells [PDF]
Metabolic remodeling is a hallmark of cancer progression and may affect tumor chemoresistance. Here we investigated by 1H-NMR/PCA analysis the metabolic profile of chemoresistant breast cancer cell subpopulations (ALDHbright cells) and their response to ...
A. Sacconi+10 more
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Retraction Note: LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis. [PDF]
Wen H, Feng H, Ma Q, Liang C.
europepmc +1 more source
Design of bioinformatic tools for integrative analysis of microRNA-mRNA interactome applied to digestive cancers [PDF]
[spa] En esta tesis se han desarrollado e implementado distintas herramientas bioinformáticas que permiten el estudio de las interacciones miRNA-mRNA en contextos celulares específicos.
Vila Casadesús, Maria
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Long non-coding RNA (LncRNA) CASC9/microRNA(miR)-590-3p/sine oculis homeobox 1 (SIX1)/NF-κB axis promotes proliferation and migration in breast cancer. [PDF]
Chang J+6 more
europepmc +1 more source
Circulating MicroRNAs in Cutaneous Melanoma Diagnosis and Prognosis [PDF]
Cutaneous melanoma represents a challenge for pharmacologists and clinicians due to their high degree of genetic and phenotypic heterogeneity. The identification of new non-invasive and informative biomarkers would therefore represent a substantial ...
Carpi, Sara+4 more
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