Results 71 to 80 of about 4,305 (116)

Association between the Mediterranean diet and metabolic syndrome with serum levels of miRNA in morbid obesity [PDF]

open access: yes, 2021
Background: The Mediterranean diet (MD) could be involved in the regulation of different miRNAs related to metabolic syndrome (MS). Methods: We analyzed the serum level of mir-let7a-5p, mir-21, mir-590, mir-107 and mir-192 in patients with morbid ...
Domínguez-Bendala, J.   +6 more
core  

Data from miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2–Versican Pathway

open access: yes, 2023
<div>Abstract<p>miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this study, we determined the expression and function of miR-590-3p in EOC.
Chun Peng   +11 more
openaire   +1 more source

A Pilot Study Investigating the Impact of High Altitude on Myostatin and Irisin Levels [PDF]

open access: yes
Many people visit and stay at high altitude due to adventure or occupation. The high-altitude environment comprises many factors alien to sea residents and detrimental to physical and mental health.
Rathor, Richa   +2 more
core   +2 more sources

CircMLH3 induces mononuclear macrophage pyroptosis in sepsis by sponging miR-590-3p to regulate TAK1 expression

open access: yesInternational Journal of Biological Macromolecules
Sepsis is a fatal syndrome characterized by uncontrolled systemic inflammatory responses. Circular RNAs (circRNAs) are involved in the modulation of various pathophysiological processes, but their potential role in sepsis has largely been unexplored. In this study, we observed differential expression of circMLH3 between healthy volunteers and septic ...
Qin, Sun   +8 more
openaire   +2 more sources

Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea [PDF]

open access: yes, 2010
Background Dysregulated expression of microRNAs (miRNAs) has been previously observed in human cancer tissues and shown promise in defining tumor status.
A Krek   +70 more
core   +3 more sources

Metformin-induced metabolic reprogramming of chemoresistant ALDHbright breast cancer cells [PDF]

open access: yes, 2014
Metabolic remodeling is a hallmark of cancer progression and may affect tumor chemoresistance. Here we investigated by 1H-NMR/PCA analysis the metabolic profile of chemoresistant breast cancer cell subpopulations (ALDHbright cells) and their response to ...
A. Sacconi   +10 more
core   +1 more source

Design of bioinformatic tools for integrative analysis of microRNA-mRNA interactome applied to digestive cancers [PDF]

open access: yes, 2017
[spa] En esta tesis se han desarrollado e implementado distintas herramientas bioinformáticas que permiten el estudio de las interacciones miRNA-mRNA en contextos celulares específicos.
Vila Casadesús, Maria
core   +2 more sources

Circulating MicroRNAs in Cutaneous Melanoma Diagnosis and Prognosis [PDF]

open access: yes, 2016
Cutaneous melanoma represents a challenge for pharmacologists and clinicians due to their high degree of genetic and phenotypic heterogeneity. The identification of new non-invasive and informative biomarkers would therefore represent a substantial ...
Carpi, Sara   +4 more
core  

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