Results 71 to 80 of about 4,615 (182)

The Impact of lncRNAs and miRNAs in Regulation of Function of Cancer Stem Cells and Progression of Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2021
Stem cells have two important features, namely the ability for self-renewal and the capacity to differentiate into some cell kinds with specialized functions. These two features are also present in cancer stem cells (CSCs). These cells have been detected
Soudeh Ghafouri-Fard   +5 more
doaj   +1 more source

Evaluation of BMP2/miRNA co-expression systems for potent therapeutic efficacy in bone-tissue regeneration [PDF]

open access: yesEuropean Cells & Materials, 2021
Reconstruction of bone defects and compensation of deficient repair mechanisms represent important goals within the field of regenerative medicine and require novel safe strategies for translation into the clinic.
TK Brenner   +9 more
doaj   +1 more source

Novel integrative genomic tool for interrogating lithium response in bipolar disorder [PDF]

open access: yes, 2015
We developed a novel integrative genomic tool called GRANITE (Genetic Regulatory Analysis of Networks Investigational Tool Environment) that can effectively analyze large complex data sets to generate interactive networks.
Alda, M   +14 more
core   +2 more sources

Introduction [PDF]

open access: yes, 2019
Inflammation plays a critical role in initiation of adaptive immunity, pathogen clearance and tissue repair. Interleukin (IL)-1β is a potent pro-inflammatory cytokine and therefore its production is tightly regulated: its secretion requires the assembly ...
Ojcius, David, Renard, Nicolas
core   +5 more sources

A review on the role of HAND2-AS1 in cancer [PDF]

open access: yes, 2023
HAND2 antisense RNA 1 (HAND2-AS1) is a newly recognized lncRNA encoded by a gene on 4q34.1. This lncRNA has 10 exons and is predicted to have a positive effect on expression of certain genes.
Abdullah, Snur Rasool   +5 more
core   +1 more source

Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto

open access: yesJurnal Kesehatan Andalas, 2021
Penemuan metode deteksi dini kanker payudara secara sensitif, spesifik dan minimal invasif merupakan kunci dalam keberhasilan pengobatan. Hal ini dapat dilakukan menggunakan biomarker yang bersirkulasi dalam plasma darah yaitu mikroRNA.
Ari Dwi Nurasih   +2 more
doaj   +1 more source

Notch pathway activation enhances cardiosphere in vitro expansion [PDF]

open access: yes, 2018
Cardiospheres (CSps) are self-assembling clusters of a heterogeneous population of poorly differentiated cells outgrowing from in vitro cultured cardiac explants.
Barile, Lucio   +6 more
core   +3 more sources

The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs

open access: yesStem Cell Reports, 2018
Summary: During reprogramming, telomere re-elongation is important for pluripotency acquisition and ensures the high quality of induced pluripotent stem cells (iPSCs), but the regulatory mechanism remains largely unknown.
Qidong Liu   +10 more
doaj   +1 more source

LncRNAs: the bridge linking RNA and colorectal cancer. [PDF]

open access: yes, 2016
Long noncoding RNAs (lncRNAs) are transcribed by genomic regions (exceeding 200 nucleotides in length) that do not encode proteins. While the exquisite regulation of lncRNA transcription can provide signals of malignant transformation, lncRNAs control ...
Chen, Yi   +18 more
core   +4 more sources

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