Results 51 to 60 of about 285,099 (189)

The miR-590 C57T SNP reduces levels of miR-590-5p and miR-590-3p, without affecting the levels of pri-miR-590 and pre-miR-590.

, 2016
(A) Quantification of pri-miR-590 by qRT-PCR normalized by GAPDH. Mean ± SD (n = 3). HEK293T cells were transfected with the pri-miR-590-WT or pri-miR-590-SNP plasmids. The empty plasmid was used as negative control.
Suresh K. Kandasamy (2794198), Steven Steinberg (582816), Scot J. Matkovich (421129), Neal Epstein (2794180), Dotti Tripodi (2794204), Garry Cutting (2794201), Xiaoping Lin (215407), Blaid Mbiyangandu (2794195), Celia P. Corona-Villalobos (2794189), Ryuya Fukunaga (2794186), M. Roselle Abraham (242563), Junaid Afzal (2794192), Susan E. Liao (2794177), Yufan Guan (2794171), Zhaoxia Huo (2794183), Theodore P. Abraham (2794174)   +15 more
core   +1 more source

Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome

Frontiers in Cell and Developmental Biology, 2021
Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno, Triin Kikas, Kristiina Lillepea, Maris Laan   +3 more
doaj   +1 more source

Additional file 3: of Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells

, 2019
Figure S3. MiR-590-3p exerted tumor-suppressive function in glioma cells. a-c. CCK-8 assay, flow cytometry analysis, migration and invasion assays were utilized to determine the influences of miR-590-3p expression alteration on biological behaviors of ...
Chunqing Yang (6271727), Jiajia Chen (187079), Jian Zheng (287758), Yixue Xue (133703), Yichen Song (6829481), Xiaobai Liu (3760144), Yunhui Liu (133710), Lianqi Shao (6309878), Shuyuan Shen (5845901), Zhen Li (49109), Xuelei Ruan (5845916)   +10 more
core   +1 more source

Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors

Journal of Immunology Research, 2022
Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou, null Yanpeng-He, null Changshun-Xie, null Fulai-Gao, null Xiaoli-Xie, null Xiukun-Chai, null Chenxi-He, null Dongqiang-Zhao   +7 more
doaj   +1 more source

Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility

Non-Coding RNA, 2023
Deregulated miRNAs are associated with colorectal cancer (CRC), with alterations depending on the tumor location. Novel tissue-specific miRNAs have been identified in different tumors and are associated with cancer.
Iael Weissberg Minutentag, Ana Laura Seneda, Mateus C. Barros-Filhos, Márcio de Carvalho, Vanessa G. P. Souza, Claudia N. Hasimoto, Marcelo P. T. Moraes, Fabio A. Marchi, Wan L. Lam, Patricia P. Reis, Sandra A. Drigo   +10 more
doaj   +1 more source

Additional file 5: of Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells

, 2019
Figure S5. The transfection efficacy was detected by qRT-PCR or western blot a. Western blot was used to examine the expression of A1CF in glioma cells treated with altering A1CF expression. Data represented mean ± SD (n=5, each group).
Chunqing Yang (6271727), Jiajia Chen (187079), Jian Zheng (287758), Yixue Xue (133703), Yichen Song (6829481), Xiaobai Liu (3760144), Yunhui Liu (133710), Lianqi Shao (6309878), Shuyuan Shen (5845901), Zhen Li (49109), Xuelei Ruan (5845916)   +10 more
core   +1 more source

Supplementary Material for: miR-590-3p Is a Novel MicroRNA in Myocarditis by Targeting Nuclear Factor Kappa-B in vivo

, 2017
Objective: Nuclear factor kappa-B (NF-κB)-induced inflammation leads to myocarditis and heart dysfunction. How microRNAs (miRNAs) contribute to this process is poorly defined. The aim of this study was to investigate whether miRNAs regulate NF-κB-induced
Zhou J. (3931118), Tian Y. (4154389), Zhao S. (3237696), Zhao Z. (3859489), Yang G. (3112701), Deng Y.-Y. (4154380), Sun T. (4154383), Zhuo X.-Z. (4144564), Liu P.-N. (4154386), Liu J.-H. (4154377)   +9 more
core   +1 more source

MAM‐Localized MANF Counteracts Microinflammatory Stress to Attenuate Mitochondrial Dysfunction and Cataractogenesis in High Myopia

Advanced Science, EarlyView.
Chronic microinflammation in high myopia suppresses MANF in lens epithelial cells. MANF normally resides within MAMs and promotes ubiquitin‐mediated degradation of the ER Ca2+ pump SERCA2. MANF loss causes pathological SERCA2 accumulation, MAM hyperassembly, and disrupted ER‐to‐mitochondria Ca2+ transfer, leading to mitochondrial failure, oxidative ...
Xin Liu, Hao Li, Ching Kang, Dongling Guo, Shuyu Liu, Jiaqi Meng, Zhiqian Huang, Yu Du, Xiangjia Zhu   +8 more
wiley   +1 more source

TiO6 as a Compensatory Structural Unit in Co‐Free, High‐Ni Layered Oxide for Durable Lithium‐Ion Batteries

Advanced Science, EarlyView.
Ti substitution stabilizes Co‐free high‐Ni layered oxides through both structural and electronic effects. TiO6 octahedra act as compensatory structural units that help interrupt cooperative Jahn–Teller distortion and suppress detrimental phase transitions, while the electron‐withdrawing inductive effect of Ti stabilizes the oxygen lattice. As a result,
Bixian Ying, Zhenjie Teng, Jun Wang, Honghong Tian, Charlotte von Petersdorff‐Campen, Rommel T. Tolla, Iuliia Mikulska, Linus Voigt, Sascha Nowak, Verena Naber, Alexander Schökel, Yuanming Liu, Michael Merz, Peter Nagel, Stefan Schuppler, Katja Frenzel, Adrian Jonas, Lena Mathies, Martin Winter, Karin Kleiner   +19 more
wiley   +1 more source

Prediction of circMARK3-miR-1273g-3p-Fgr interaction.

, 2019
(A) miR-1273g-3p targeting Fgr. (B) miR-1273g-3p targeting circMARK3. (C) Prediction of circMARK3-miRNA-mRNA interaction. The base-pairing and the minimum free energy (mfe) were predicted using the RNA hybrid program. (D-F) The relative expression levels
Yuting Guo (2223820), Xiyu Zhu (3719617), Qing Zhou (52712), Congcong Tian (1650379), Bing Gong (1602628), Dongjin Wang (35909), Rui Zhao (43391), Xinlong Tang (6894287)   +7 more
core   +1 more source