Results 51 to 60 of about 226,592 (181)

Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors

Journal of Immunology Research, 2022
Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou, null Yanpeng-He, null Changshun-Xie, null Fulai-Gao, null Xiaoli-Xie, null Xiukun-Chai, null Chenxi-He, null Dongqiang-Zhao   +7 more
doaj   +1 more source

Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome

Frontiers in Cell and Developmental Biology, 2021
Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno, Triin Kikas, Kristiina Lillepea, Maris Laan   +3 more
doaj   +1 more source

Che-1/miR-590-3p/TAZ axis sustains multiple myeloma disease.

, 2023
Abstract Multiple myeloma (MM) is a blood disease characterized by the malignant accumulation of monoclonal plasma cells in the bone marrow. Among the pathological consequences of MM, defects in osteogenesis characterized by osteolytic lesions, osteopenia, and pathologic fractures are frequently described.
Maurizio Fanciulli, Tiziana Bruno, Valeria Catena, Giacomo Corleone, Clelia Cortile, Maria Cappelletto, barbara bellei, Francesca De Nicola, Svitlana Gumenyuk, Francesco Marchesi, Ombretta Annibali, Giovanni Blandino, Silvia Di Agostino   +12 more
openaire   +1 more source

Additional file 3: of Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells

, 2019
Figure S3. MiR-590-3p exerted tumor-suppressive function in glioma cells. a-c. CCK-8 assay, flow cytometry analysis, migration and invasion assays were utilized to determine the influences of miR-590-3p expression alteration on biological behaviors of ...
Chunqing Yang (6271727), Jiajia Chen (187079), Jian Zheng (287758), Yixue Xue (133703), Yichen Song (6829481), Xiaobai Liu (3760144), Yunhui Liu (133710), Lianqi Shao (6309878), Shuyuan Shen (5845901), Zhen Li (49109), Xuelei Ruan (5845916)   +10 more
core   +1 more source

Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility

Non-Coding RNA, 2023
Deregulated miRNAs are associated with colorectal cancer (CRC), with alterations depending on the tumor location. Novel tissue-specific miRNAs have been identified in different tumors and are associated with cancer.
Iael Weissberg Minutentag, Ana Laura Seneda, Mateus C. Barros-Filhos, Márcio de Carvalho, Vanessa G. P. Souza, Claudia N. Hasimoto, Marcelo P. T. Moraes, Fabio A. Marchi, Wan L. Lam, Patricia P. Reis, Sandra A. Drigo   +10 more
doaj   +1 more source

Additional file 5: of Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells

, 2019
Figure S5. The transfection efficacy was detected by qRT-PCR or western blot a. Western blot was used to examine the expression of A1CF in glioma cells treated with altering A1CF expression. Data represented mean ± SD (n=5, each group).
Chunqing Yang (6271727), Jiajia Chen (187079), Jian Zheng (287758), Yixue Xue (133703), Yichen Song (6829481), Xiaobai Liu (3760144), Yunhui Liu (133710), Lianqi Shao (6309878), Shuyuan Shen (5845901), Zhen Li (49109), Xuelei Ruan (5845916)   +10 more
core   +1 more source

Supplementary Material for: miR-590-3p Is a Novel MicroRNA in Myocarditis by Targeting Nuclear Factor Kappa-B in vivo

, 2017
Objective: Nuclear factor kappa-B (NF-κB)-induced inflammation leads to myocarditis and heart dysfunction. How microRNAs (miRNAs) contribute to this process is poorly defined. The aim of this study was to investigate whether miRNAs regulate NF-κB-induced
Zhou J. (3931118), Tian Y. (4154389), Zhao S. (3237696), Zhao Z. (3859489), Yang G. (3112701), Deng Y.-Y. (4154380), Sun T. (4154383), Zhuo X.-Z. (4144564), Liu P.-N. (4154386), Liu J.-H. (4154377)   +9 more
core   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

MiR-28-3p regulates high glucose-induced endothelial dysfunction by targeting CXXC5

, 2023
Introduction Data from the CEO database show that microRNA (miR)-28-3p levels are elevated in diabetic patients. Nevertheless, the role of miR-28-3p in peripheral artery disease with diabetes has not been investigated. Material and methods The levels of
Ziheng Wu, Jun Pan, Linjun Wang, Songmao Wang, Xin Fang, Yangmin Dong, Chenyang Qiu   +6 more
core   +1 more source