Results 31 to 40 of about 4,252 (145)

Correction for: The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma [PDF]

Aging, 2022
Wan, Zhongzhong, Li, Xingrun, Luo, Xinru, Wang, Bofan, Zhou, Xiang, Chen, Ao   +5 more
openaire   +3 more sources

Hsa-miR-137, hsa-miR-520e and hsa-miR-590-3p perform crucial roles in Lynch syndrome [PDF]

Oncology Letters, 2016
The aim of the present study was to identify the differentially expressed microRNAs (DEMs) between Lynch syndrome (LS) and the normal colonic (N-C) control samples, predict the target genes (TGs) and analyze the potential functions of the DEMs and TGs.
Changyu, Zhou, Jiayu, Li, Jiarui, Li, Yingchun, Wan, Tao, Li, Piyong, Ma, Yingjian, Wang, Haiyan, Sang   +7 more
openaire   +4 more sources

The clinical significance of miR-590-3p in acute myeloid leukemia and potential regulatory mechanism based on bioinformatic prediction

Türk Biyokimya Dergisi
Acute myeloid leukaemia (AML) usually has a poor prognosis, and an effective prognostic marker is needed. MicroRNAs (miRNAs) have potential as prognostic markers. Therefore, the prognostic diagnostic role and potential regulatory mechanisms of miR-590-3p
Ma Li, Qu Dongxia, Chi Xiaomeng, Yang Aiying, Zou Xin   +4 more
doaj   +2 more sources

Integrative bioinformatic and clinical validation reveals dynamic regulation of circulating microRNAs before and after antiretroviral therapy in HIV-positive patients [PDF]

Scientific Reports
MicroRNAs (miRNAs) play a crucial role in gene regulation, including HIV, where they influence viral replication and immune response. This study aims to identify key miRNAs involved in HIV pathogenesis, using bioinformatics and cohort validation to ...
Haktan Sonmez, Zofia Wicik, Ceren Eyileten, Sara Ahmadova, Ömer Fehmi Tabak, Bilgul Mete, Ilker Inanc Balkan, Oner Suzer, Andleeb Shahzadi   +8 more
doaj   +2 more sources

Inhibiting ubiquitin conjugating enzyme E2 N by microRNA‐590‐3p reduced cell growth of cervical carcinoma

Kaohsiung Journal of Medical Sciences, 2020
The ubiquitin conjugating enzyme E2 N (UBE2N) has been reported to be involved in the tumorigenesis of several tumors, but its function in cervical carcinoma has not been investigated yet.
Ting‐Ting Song, Fei Xu, Wei Wang
doaj   +1 more source

Exosomal transfer of microRNA-590-3p between renal tubular epithelial cells after renal ischemia-reperfusion injury regulates autophagy by targeting TRAF6

Chinese Medical Journal, 2022
. Background:. Acute kidney injury (AKI) is a common complication in patients, especially elderly patients, who undergo cardiac surgery with cardiopulmonary bypass. Studies have indicated a protective role of autophagy in AKI.
Yimeng Chen, Congya Zhang, Yingjie Du, Xiying Yang, Min Liu, Wenjing Yang, Guiyu Lei, Guyan Wang, Jing Ni   +8 more
doaj   +1 more source

Non-coding RNA Activated by DNA Damage: Review of Its Roles in the Carcinogenesis

Frontiers in Cell and Developmental Biology, 2021
Long intergenic non-coding RNA 00657 (LINC00657) or “non-coding RNA activated by DNA damage” (NORAD) is an extremely conserved and copious long non-coding RNA (lncRNA). This transcript has pivotal role in the preservation of genome integrity.
Soudeh Ghafouri-Fard, Tahereh Azimi, Bashdar Mahmud Hussen, Atefe Abak, Mohammad Taheri, Nader Akbari Dilmaghani   +5 more
doaj   +1 more source

Altered Expression of Specific MicroRNAs in Plasma of Aneurysmal Subarachnoid Hemorrhage Patients

Frontiers in Neurology, 2022
BackgroundAneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition with high disability and mortality. MicroRNAs (miRNAs) are reported to play a modulating role in aSAH.
Lina Zheng, Xin Zhang, Liping Liu, Yuehua Pu   +3 more
doaj   +1 more source

Identification of potential microRNA diagnostic panels and uncovering regulatory mechanisms in breast cancer pathogenesis

Scientific Reports, 2022
Early diagnosis of breast cancer (BC), as the most common cancer among women, increases the survival rate and effectiveness of treatment. MicroRNAs (miRNAs) control various cell behaviors, and their dysregulation is widely involved in pathophysiological ...
Zahra Sharifi, Mahmood Talkhabi, Sara Taleahmad   +2 more
doaj   +1 more source

Circulating miRNAs in Serum as Biomarkers for Early Diagnosis of Non-small Cell Lung Cancer

Frontiers in Genetics, 2021
BackgroundNon-small cell lung cancer (NSCLC) accounts for about 85% of lung cancers. This study aimed to discover the potential miRNA biomarkers for early detection of NSCLC.MethodsTotal circulating miRNAs were extracted from six patients and six ...
Xiaotong Duan, Simiao Qiao, Dianhe Li, Shangbiao Li, Zhihao Zheng, Qin Wang, Xiaoxia Zhu   +6 more
doaj   +1 more source