Results 31 to 40 of about 226,592 (181)

circEFR3A promotes breast cancer progression by sponging miR-590-3p to upregulate androgen receptor expression. [PDF]

Oncol Lett
Circular (circ)RNA, a type of non-coding RNA, serves a critical role in several diseases, including cancer. The present study aimed to elucidate the involvement of hsa_circ_0006522 (circEFR3A) in the advancement of breast cancer (BC) and uncover the molecular mechanisms behind its function.
Mi Y, Wang X, Song H, Wu Z, Li S, Liu F, Liu W, Sang M, Geng C.   +8 more
europepmc   +3 more sources

MiR-590-3p promotes proliferation and metastasis of colorectal cancer via Hippo pathway. [PDF]

Oncotarget, 2017
Studies reported that miR-590-3p was involved in human cancer progression. However, its roles of oncogene or anti-oncogene in malignancies still remain elusive. This study was aimed to investigate the effect of miR-590-3p on the cell proliferation and metastasis via Hippo pathway in colorectal cancer (CRC).
Sun ZQ, Shi K, Zhou QB, Zeng XY, Liu J, Yang SX, Wang QS, Li Z, Wang GX, Song JM, Yuan WT, Wang HJ.   +11 more
europepmc   +4 more sources

Elevated hsa-miR-590-3p expression down-regulates HMGB2 expression and contributes to the severity of IgA nephropathy. [PDF]

J Cell Mol Med, 2019
AbstractPeripheral blood mononuclear cells (PBMCs) play important roles in the pathogenesis of IgA nephropathy (IgAN). Our study aimed to provide a deep understanding of IgAN and focused on the dysregulation of hsa‐miR‐590‐3p and its target gene HMGB2 in PBMCs.
Zhai Y, Qi Y, Long X, Dou Y, Liu D, Cheng G, Xiao J, Liu Z, Zhao Z.   +8 more
europepmc   +4 more sources

MiR-590-3p suppresses epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma by inhibiting SIP1 expression. [PDF]

Oncotarget, 2017
The functional roles and clinical significances of miR-590-3p in ICC remain unclear. In the current study, we investigated the expression of miR-590-3p in tissues and sera of ICC by real-time quantitative polymerase chain reaction. We found miR-590-3p was significantly down-regulated in the sera and tissues of ICC patients, especially in those patients
Zu C, Liu S, Cao W, Liu Z, Qiang H, Li Y, Cheng C, Ji L, Li J, Li J.   +9 more
europepmc   +4 more sources

Inhibiting ubiquitin conjugating enzyme E2 N by microRNA‐590‐3p reduced cell growth of cervical carcinoma

Kaohsiung Journal of Medical Sciences, 2020
The ubiquitin conjugating enzyme E2 N (UBE2N) has been reported to be involved in the tumorigenesis of several tumors, but its function in cervical carcinoma has not been investigated yet.
Ting‐Ting Song, Fei Xu, Wei Wang
doaj   +1 more source

Exosomal transfer of microRNA-590-3p between renal tubular epithelial cells after renal ischemia-reperfusion injury regulates autophagy by targeting TRAF6

Chinese Medical Journal, 2022
. Background:. Acute kidney injury (AKI) is a common complication in patients, especially elderly patients, who undergo cardiac surgery with cardiopulmonary bypass. Studies have indicated a protective role of autophagy in AKI.
Yimeng Chen, Congya Zhang, Yingjie Du, Xiying Yang, Min Liu, Wenjing Yang, Guiyu Lei, Guyan Wang, Jing Ni   +8 more
doaj   +1 more source

Additional file 1 of Functional role and epithelial to mesenchymal transition of the miR-590-3p/MDM2 axis in hepatocellular carcinoma

, 2023
Additional file 1: Figure S1. miR-590-3p directly targets EMT-TF SLUG, ZEB1, and ZEB2 in HCC, as determined by bioinformatics analysis (A) CSmiRTar database analysis showing SLUG, ZEB1 and ZEB2 as miR-590-3p potential target genes.
Alaa Ibrahem Youssef (15406260), Gehad Mahmoud Khaled (15406263), Asma Amleh (265512)   +2 more
core   +1 more source

miR-22-3p regulates HCC cell EMT, migration, and invasion through the miR-22-3p-CBL-SPRY2 axis.

, 2023
A. Immunoblotting of CBL and SPRY2 in the three cell lines: HepG2 mock cells, HepG2 overexpressing miR-22-3p cells, and HepG2 overexpressing miR-22-3p plus CBL cells. B.
Dahu Chen (528122), Shuaishuai Cui (11690234), Xing Wang (154377), Yuanyuan Chen (165812), Yunfei Guo (3601046)   +4 more
core   +1 more source

Non-coding RNA Activated by DNA Damage: Review of Its Roles in the Carcinogenesis

Frontiers in Cell and Developmental Biology, 2021
Long intergenic non-coding RNA 00657 (LINC00657) or “non-coding RNA activated by DNA damage” (NORAD) is an extremely conserved and copious long non-coding RNA (lncRNA). This transcript has pivotal role in the preservation of genome integrity.
Soudeh Ghafouri-Fard, Tahereh Azimi, Bashdar Mahmud Hussen, Atefe Abak, Mohammad Taheri, Nader Akbari Dilmaghani   +5 more
doaj   +1 more source

Altered Expression of Specific MicroRNAs in Plasma of Aneurysmal Subarachnoid Hemorrhage Patients

Frontiers in Neurology, 2022
BackgroundAneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition with high disability and mortality. MicroRNAs (miRNAs) are reported to play a modulating role in aSAH.
Lina Zheng, Xin Zhang, Liping Liu, Yuehua Pu   +3 more
doaj   +1 more source