Results 11 to 20 of about 285,099 (189)

UCA1 promotes cell proliferation and invasion of gastric cancer by targeting CREB1 sponging to miR‐590‐3p [PDF]

Cancer Medicine, 2018
Long noncoding RNAs (lncRNAs) have emerged as regulators in a variety of biological processes, including carcinogenesis in human cancer. UCA1 has been reported to be upregulated in gastric cancer (GC); however, the underlying functional roles of UCA1 in ...
Lei Gu, Lie‐sheng Lu, Dong‐lei Zhou, Zhong‐chen Liu   +3 more
doaj   +4 more sources

Expression of serum microRNAs, mir-182-5p, and miR-590-3p and its clinical significance in neonatal sepsis

Egyptian Pediatric Association Gazette
Background Neonatal sepsis is one of the life-threatening diseases. MicroRNAs are non-coding RNAs that play vital roles in various diseases. Methods This study included 50 neonates with sepsis and 60 healthy controls. RNA extraction and assessment of mir-
Soha M. Hamdy, Yomna A. Othman, Omayma O. Abdelaleem, Rehab G. Abd El-Hamid, Doaa Y. Ali   +4 more
doaj   +3 more sources

Long Noncoding RNA Nuclear Paraspeckle Assembly Transcript 1 Promotes Progression and Angiogenesis of Esophageal Squamous Cell Carcinoma Through miR-590-3p/MDM2 Axis [PDF]

Frontiers in Oncology, 2021
Angiogenesis has been identified as one of the hallmarks of cancer and aggravates cancer development and progression. Accumulating evidence indicated that long noncoding RNAs (lncRNAs) are powerful factors in regulating various cancer behaviors.
Jing Luo, Jing Luo, Kai Xie, Kai Xie, Xiang Gao, Yu Yao, Gaoming Wang, Gaoming Wang, Chenye Shao, Xiaokun Li, Yang Xu, Binhui Ren, Liwen Hu, Yi Shen   +13 more
doaj   +2 more sources

LncRNA PCGEM1 induces proliferation and migration in non-small cell lung cancer cells through modulating the miR-590-3p/SOX11 axis

BMC Pulmonary Medicine, 2021
Background Non-small cell lung cancer (NSCLC) is one of the most prevalent cancers. As reported, long non-coding RNAs (lncRNAs) induce various biological behaviors in cancers.
Huanshun Wen, Hongxiang Feng, Qianli Ma, Chaoyang Liang   +3 more
doaj   +2 more sources

Che-1/miR-590-3p/TAZ axis sustains multiple myeloma disease. [PDF]

Leukemia
Multiple myeloma (MM) is a blood disease characterized by the malignant accumulation of monoclonal plasma cells in the bone marrow. Among the pathological consequences of the MM, defects in osteogenesis characterized by osteolytic lesions, osteopenia ...
Bruno T, Catena V, Corleone G, Cortile C, Cappelletto MC, Bellei B, De Nicola F, Amadio B, Gumenyuk S, Marchesi F, Annibali O, Blandino G, Fanciulli M, Di Agostino S.   +13 more
europepmc   +3 more sources

MiR-590-3p promotes ovarian cancer growth and metastasis via a novel FOXA2-versican pathway [PDF]

Cancer Research, 2018
miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this study, we determined the expression and function of miR-590-3p in EOC.
Bernaudo, Stefanie, Jelena Brkić, Barbara C. Vanderhyden, Stefanie Bernaudo, Ye, Gang, Gang Ye, Vanderhyden, Barbara C., Yang, Burton B., Chun Peng, Asma Amleh, Refky, Basel, Salem, Mohamed, Peng, Chun, Burton B. Yang, Basel Refky, O\u27Brien, Jacob A., Shawer, Heba, Krylov, Sergey N., Amleh, Asma, Mohamed Salem, Jacob A. O'Brien, Sergey N. Krylov, Heba Shawer, Brkić, Jelena   +23 more
core   +3 more sources

Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells [PDF]

Journal of Experimental & Clinical Cancer Research, 2019
Background Glioma is the most common and lethal type of malignant brain tumor. Accumulating evidence has highlighted that RNA binding protein APOBEC1 complementation factor (A1CF) is involved in various cellular processes by modulating RNA expression ...
Yichen Song, Lianqi Shao, Yixue Xue, Xuelei Ruan, Xiaobai Liu, Chunqing Yang, Jian Zheng, Shuyuan Shen, Jiajia Chen, Zhen Li, Yunhui Liu   +10 more
doaj   +2 more sources

miR-590-3p Targets Cyclin G2 and FOXO3 to Promote Ovarian Cancer Cell Proliferation, Invasion, and Spheroid Formation. [PDF]

Int J Mol Sci, 2019
Ovarian cancer is the leading cause of death from gynecological cancers. MicroRNAs (miRNAs) are small, non-coding RNAs that interact with the 3′ untranslated region (3′ UTR) of target genes to repress their expression.
Salem M, Shan Y, Bernaudo S, Peng C.
europepmc   +5 more sources

Expression of LncRNA HCG11 and miR-590-3p in Squamous Carcinoma of Cervix and Their Relationship with Prognosis

Zhongliu Fangzhi Yanjiu, 2018
Objective To investigate the expression of long non-coding RNA (LncRNA) HCG11 and miR-590-3p in squamous carcinoma of cervix and paired adjacent tissues, and their correlation with patients' clinical data and prognosis.
CHEN Xiaojie, LIU Ping
doaj   +2 more sources

Common miR-590 Variant rs6971711 Present Only in African Americans Reduces miR-590 Biogenesis.

PLoS ONE, 2016
MicroRNAs (miRNAs) are recognized as important regulators of cardiac development, hypertrophy and fibrosis. Recent studies have demonstrated that genetic variations which cause alterations in miRNA:target interactions can lead to disease. We hypothesized
Xiaoping Lin, Steven Steinberg, Suresh K Kandasamy, Junaid Afzal, Blaid Mbiyangandu, Susan E Liao, Yufan Guan, Celia P Corona-Villalobos, Scot J Matkovich, Neal Epstein, Dotti Tripodi, Zhaoxia Huo, Garry Cutting, Theodore P Abraham, Ryuya Fukunaga, M Roselle Abraham   +15 more
doaj   +2 more sources