Results 21 to 30 of about 4,814 (170)

Long non-coding RNA MALAT1 promotes cell proliferation, migration and invasion by targeting miR-590-3p in osteosarcoma. [PDF]

Exp Ther Med, 2022
Osteosarcoma (OS) is a common malignant bone cancer and commonly occurs in adolescents and children. Long non-coding RNAs (lncRNAs) play major roles in cancer cell proliferation and metastasis. The present study aimed to investigate the potential molecular mechanism of lncRNA MALAT1 in OS.
Zhao H, Wang Y, Hou W, Ding X, Wang W.
europepmc   +3 more sources

MiR-590-3p regulates proliferation, migration and collagen synthesis of cardiac fibroblast by targeting ZEB1. [PDF]

J Cell Mol Med, 2020
AbstractPrevious studies have implicated the attractive and promising role of miR‐590‐3p to restore the cardiac function following myocardial infarction (MI). However, the molecular mechanisms for how miR‐590‐3p involves in cardiac fibrosis remain largely unexplored. Using human cardiac fibroblasts (HCFs) as the cellular model, luciferase report assay,
Yuan X, Pan J, Wen L, Gong B, Li J, Gao H, Tan W, Liang S, Zhang H, Wang X.   +9 more
europepmc   +3 more sources

Correction for: The miR-590-3p/CFHR3/STAT3 signaling pathway promotes cell proliferation and metastasis in hepatocellular carcinoma. [PDF]

Aging (Albany NY), 2022
Wan Z, Li X, Luo X, Wang B, Zhou X, Chen A.   +5 more
europepmc   +3 more sources

lncRNA SNHG4 modulates colorectal cancer cell cycle and cell proliferation through regulating miR-590-3p/CDK1 axis. [PDF]

Aging (Albany NY), 2021
Colorectal cancer (CRC) is a prevalent malignancy worldwide. The development of genome sequencing technology has allowed the discovery that epigenetic regulation might play a critical role in CRC tumorigenesis. In the present study, we found that the long noncoding RNA (lncRNA) SNHG4 was dramatically increased in CRC tissue samples and cell lines based
Zhou Z, Tan F, Pei Q, Li C, Zhou Y, Li Y, Pei H.   +6 more
europepmc   +3 more sources

LncRNA NEAT1 promotes apoptosis and inflammation in LPS-induced sepsis models by targeting miR-590-3p. [PDF]

Exp Ther Med, 2020
Sepsis is a complication of infection caused by disease or trauma. Increasing evidence have shown that long noncoding RNAs (lncRNAs) are involved in the regulation of sepsis. However, the mechanism of lncRNA nuclear enriched abundant transcript 1 (NEAT1) in the regulation of sepsis progression remains to be elucidated. Lipopolysaccharide (LPS) was used
Liu L, Liu F, Sun Z, Peng Z, You T, Yu Z.   +5 more
europepmc   +4 more sources

circEFR3A promotes breast cancer progression by sponging miR-590-3p to upregulate androgen receptor expression. [PDF]

Oncol Lett
Circular (circ)RNA, a type of non-coding RNA, serves a critical role in several diseases, including cancer. The present study aimed to elucidate the involvement of hsa_circ_0006522 (circEFR3A) in the advancement of breast cancer (BC) and uncover the molecular mechanisms behind its function.
Mi Y, Wang X, Song H, Wu Z, Li S, Liu F, Liu W, Sang M, Geng C.   +8 more
europepmc   +2 more sources

MiR-590-3p promotes proliferation and metastasis of colorectal cancer via Hippo pathway. [PDF]

Oncotarget, 2017
Studies reported that miR-590-3p was involved in human cancer progression. However, its roles of oncogene or anti-oncogene in malignancies still remain elusive. This study was aimed to investigate the effect of miR-590-3p on the cell proliferation and metastasis via Hippo pathway in colorectal cancer (CRC).
Sun ZQ, Shi K, Zhou QB, Zeng XY, Liu J, Yang SX, Wang QS, Li Z, Wang GX, Song JM, Yuan WT, Wang HJ.   +11 more
europepmc   +4 more sources

The new world of RNA diagnostics and therapeutics [PDF]

, 2023
The 5th Workshop IRE on Translational Oncology was held in Rome (Italy) on 27–28 March at the IRCCS Regina Elena National Cancer Institute. This meeting entitled “The New World of RNA diagnostics and therapeutics” highlightes the significant progress in ...
Alina Catalina Palcau, Ana Belén Díaz Méndez, and Gennaro Ciliberto, Brid M. Ryan, Claudio Pulito, Eleni Anastasiadou, Gabriella Sozzi, George A. Calin, Giovanni Blandino, Giulia Regazzo, Jit Kong Cheong, Laura Monteonofrio, Luigi Fattore, Marco Marcia, Maria Chiara Cappelletto, Ranit Aharonov, Roberto Dinami, Rosanna Sestito, Rossella Loria   +18 more
core   +4 more sources

MiR-590-3p suppresses epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma by inhibiting SIP1 expression. [PDF]

Oncotarget, 2017
The functional roles and clinical significances of miR-590-3p in ICC remain unclear. In the current study, we investigated the expression of miR-590-3p in tissues and sera of ICC by real-time quantitative polymerase chain reaction. We found miR-590-3p was significantly down-regulated in the sera and tissues of ICC patients, especially in those patients
Zu C, Liu S, Cao W, Liu Z, Qiang H, Li Y, Cheng C, Ji L, Li J, Li J.   +9 more
europepmc   +4 more sources

Inhibiting ubiquitin conjugating enzyme E2 N by microRNA‐590‐3p reduced cell growth of cervical carcinoma

Kaohsiung Journal of Medical Sciences, 2020
The ubiquitin conjugating enzyme E2 N (UBE2N) has been reported to be involved in the tumorigenesis of several tumors, but its function in cervical carcinoma has not been investigated yet.
Ting‐Ting Song, Fei Xu, Wei Wang
doaj   +1 more source