Multi-omic analyses in Abyssinian cats with primary renal amyloid deposits [PDF]
, 2021 The amyloidoses constitute a group of diseases occurring in humans and animals that are characterized by abnormal deposits of aggregated proteins in organs, affecting their structure and function.
99 Lives Consortium +15 more
core +9 more sources
Circulating miRNAs in Serum as Biomarkers for Early Diagnosis of Non-small Cell Lung Cancer
Frontiers in Genetics, 2021 BackgroundNon-small cell lung cancer (NSCLC) accounts for about 85% of lung cancers. This study aimed to discover the potential miRNA biomarkers for early detection of NSCLC.MethodsTotal circulating miRNAs were extracted from six patients and six ...
Xiaotong Duan +6 more
doaj +1 more source
A statistically inferred microRNA network identifies breast cancer target miR-940 as an actin cytoskeleton regulator [PDF]
, 2015 International audienceMiRNAs are key regulators of gene expression. By binding to many genes, they create a complex network of gene co-regulation. Here, using a network-based approach, we identified miRNA hub groups by their close connections and common ...
Bhajun, Ricky +9 more
core +3 more sources
Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the expression of long non-coding RNA (LncRNA) HCG11 and miR-590-3p in squamous carcinoma of cervix and paired adjacent tissues, and their correlation with patients' clinical data and prognosis.
CHEN Xiaojie, LIU Ping
doaj +1 more source
LncRNAs: the bridge linking RNA and colorectal cancer. [PDF]
, 2016 Long noncoding RNAs (lncRNAs) are transcribed by genomic regions (exceeding 200 nucleotides in length) that do not encode proteins. While the exquisite regulation of lncRNA transcription can provide signals of malignant transformation, lncRNAs control ...
Chen, Yi +18 more
core +4 more sources
A review on the role of long non-coding RNA prostate androgen-regulated transcript 1 (PART1) in the etiology of different disorders [PDF]
, 2023 LncRNA prostate androgen-regulated transcript 1 (PART1) is an important lncRNA in the carcinogenesis whose role has been firstly unraveled in prostate cancer. Expression of this lncRNA is activated by androgen in prostate cancer cells.
Abdullah, Snur Rasool +6 more
core +1 more source
Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea [PDF]
, 2010 Background Dysregulated expression of microRNAs (miRNAs) has been previously observed in human cancer tissues and shown promise in defining tumor status.
Zhiguang Li +6 more
core +2 more sources
miR-590-3p is a novel microRNA which suppresses osteosarcoma progression by targeting SOX9
Biomedicine & Pharmacotherapy, 2018 Osteosarcoma is the most common primary bone malignancy and arises primarily in the metaphyseal ends of long bones in children and adolescents. m iR-590 has been found to have anti-tumor effects in many other cancers. However, the role of miR-590-3p in osteosarcoma is poorly understood. In this study, we show that miR-590-3p was significantly decreased
Wan-Tao, Wang +5 more
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2021 Stem cells have two important features, namely the ability for self-renewal and the capacity to differentiate into some cell kinds with specialized functions. These two features are also present in cancer stem cells (CSCs). These cells have been detected
Soudeh Ghafouri-Fard +5 more
doaj +1 more source
Profiling microRNAs in individuals at risk of progression to rheumatoid arthritis [PDF]
, 2017 Background: Individuals at risk of rheumatoid arthritis (RA) demonstrate systemic autoimmunity in the form of anti-citrullinated peptide antibodies (ACPA). MicroRNAs (miRNAs) are implicated in established RA.
AV Churov +28 more
core +2 more sources