Results 41 to 50 of about 4,252 (145)
miR-590-3p is a novel microRNA which suppresses osteosarcoma progression by targeting SOX9
Biomedicine & Pharmacotherapy, 2018 Osteosarcoma is the most common primary bone malignancy and arises primarily in the metaphyseal ends of long bones in children and adolescents. m iR-590 has been found to have anti-tumor effects in many other cancers. However, the role of miR-590-3p in osteosarcoma is poorly understood. In this study, we show that miR-590-3p was significantly decreased
Wan-Tao, Wang +5 more
openaire +2 more sources
miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2–Versican Pathway [PDF]
Cancer Research, 2018 Abstract miRNAs play important roles in gene regulation, and their dysregulation is associated with many diseases, including epithelial ovarian cancer (EOC). In this study, we determined the expression and function of miR-590-3p in EOC.
Mohamed Salem +11 more
openaire +2 more sources
Frontiers in Cell and Developmental Biology, 2021 Stem cells have two important features, namely the ability for self-renewal and the capacity to differentiate into some cell kinds with specialized functions. These two features are also present in cancer stem cells (CSCs). These cells have been detected
Soudeh Ghafouri-Fard +5 more
doaj +1 more source
Evaluation of BMP2/miRNA co-expression systems for potent therapeutic efficacy in bone-tissue regeneration [PDF]
European Cells & Materials, 2021 Reconstruction of bone defects and compensation of deficient repair mechanisms represent important goals within the field of regenerative medicine and require novel safe strategies for translation into the clinic.
TK Brenner +9 more
doaj +1 more source
Che-1/miR-590-3p/TAZ axis sustains multiple myeloma disease.
, 2023 Abstract Multiple myeloma (MM) is a blood disease characterized by the malignant accumulation of monoclonal plasma cells in the bone marrow. Among the pathological consequences of MM, defects in osteogenesis characterized by osteolytic lesions, osteopenia, and pathologic fractures are frequently described.
Maurizio Fanciulli +12 more
openaire +1 more source
The miR-590/Acvr2a/Terf1 Axis Regulates Telomere Elongation and Pluripotency of Mouse iPSCs
Stem Cell Reports, 2018 Summary: During reprogramming, telomere re-elongation is important for pluripotency acquisition and ensures the high quality of induced pluripotent stem cells (iPSCs), but the regulatory mechanism remains largely unknown.
Qidong Liu +10 more
doaj +1 more source
Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto
Jurnal Kesehatan Andalas, 2021 Penemuan metode deteksi dini kanker payudara secara sensitif, spesifik dan minimal invasif merupakan kunci dalam keberhasilan pengobatan. Hal ini dapat dilakukan menggunakan biomarker yang bersirkulasi dalam plasma darah yaitu mikroRNA.
Ari Dwi Nurasih +2 more
doaj +1 more source
ATF-3/miR-590/GOLPH3 signaling pathway regulates proliferation of breast cancer
BMC Cancer, 2018 Background Breast cancer is one of the leading causes of death in women worldwide. Fast growth is the important character of breast cancer, which makes sure the subsequent metastasize and invasion breast cancer.
Qiong Song +8 more
doaj +1 more source
Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome
Frontiers in Cell and Developmental Biology, 2021 Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno +3 more
doaj +1 more source
Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors
Journal of Immunology Research, 2022 Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou +7 more
doaj +1 more source