Results 61 to 70 of about 4,814 (170)

ATF-3/miR-590/GOLPH3 signaling pathway regulates proliferation of breast cancer

BMC Cancer, 2018
Background Breast cancer is one of the leading causes of death in women worldwide. Fast growth is the important character of breast cancer, which makes sure the subsequent metastasize and invasion breast cancer.
Qiong Song, Qiu Chen, Qimin Wang, Longqiu Yang, Dongdong Lv, Guangli Jin, Jiaying Liu, Baolin Li, Xuejie Fei   +8 more
doaj   +1 more source

Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma. [PDF]

Theranostics, 2018
Over 70% of head & neck squamous cell carcinoma (HNSCC) patients carry TP53 oncogenic mutations. Here we studied the role of specific tumor-derived mutant p53 proteins in the aberrant transcription of long non-coding (lnc) MIR205HG gene in head and ...
Di Agostino S, Valenti F, Sacconi A, Fontemaggi G, Pallocca M, Pulito C, Ganci F, Muti P, Strano S, Blandino G.   +9 more
europepmc   +3 more sources

Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors

Journal of Immunology Research, 2022
Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou, null Yanpeng-He, null Changshun-Xie, null Fulai-Gao, null Xiaoli-Xie, null Xiukun-Chai, null Chenxi-He, null Dongqiang-Zhao   +7 more
doaj   +1 more source

Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome

Frontiers in Cell and Developmental Biology, 2021
Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno, Triin Kikas, Kristiina Lillepea, Maris Laan   +3 more
doaj   +1 more source

The Quest for New Approaches in Myocarditis and Inflammatory Cardiomyopathy [PDF]

, 2016
Myocarditis is a diverse group of heart-specific immune processes classified by clinical and histopathological manifestations. Up to 40% of dilated cardiomyopathy is associated with inflammation or viral infection.
Cooper, Leslie T., Eriksson, Urs, Heymans, Stephane, Lehtonen, Jukka   +3 more
core   +1 more source

The Effect of Chemotherapy in Gestational Trophoblastic Disease on Infertility: A Review on Pathophysiologic Mechanism [PDF]

, 2021
Today, young women infertility through chemotherapy has become a global challenge. Chemotherapy destructs the malignant cells by reactive oxygen species (ROS) production and inflammatory factors secretion; these factors can also destruct the ovarian and ...
Ebrahimi, Maryam, Eslamnik , Parvinsadat, Javan, Mohammad Reza, Malmir, Ali, Moghaddasi, Mana, Sadeghi-Goughari, Bahar   +5 more
core   +2 more sources

Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility

Non-Coding RNA, 2023
Deregulated miRNAs are associated with colorectal cancer (CRC), with alterations depending on the tumor location. Novel tissue-specific miRNAs have been identified in different tumors and are associated with cancer.
Iael Weissberg Minutentag, Ana Laura Seneda, Mateus C. Barros-Filhos, Márcio de Carvalho, Vanessa G. P. Souza, Claudia N. Hasimoto, Marcelo P. T. Moraes, Fabio A. Marchi, Wan L. Lam, Patricia P. Reis, Sandra A. Drigo   +10 more
doaj   +1 more source

Long Noncoding RNA PART1 Promotes Hepatocellular Carcinoma Progression via Targeting miR-590-3p/HMGB2 Axis.

OncoTargets and therapy, 2020
In East Asia, hepatocellular carcinoma (HCC) is one of the most commonly diagnosed cancer types. Long noncoding RNA (lncRNA) prostate androgen-regulated transcript 1 (PART1) was reported to play crucial roles in regulating cancer progression. However, roles and mechanisms of action of PART1 in hepatocellular carcinoma (HCC) still remain unknown ...
Pu,Jian, Tan,Chuan, Shao,Zesheng, Wu,Xianjian, Zhang,Ya, Xu,Zuoming, Wang,Jianchu, Tang,Qianli, Wei,Huamei   +8 more
openaire   +3 more sources

Long noncoding RNA LINC01615 promotes keloid development via sponging miR-590-3p to regulate FGF2 expression [PDF]

, 2020
Abstract Background A keloid is a benign human skin tumor that resulted by fibrous overgrowths during wound healing. Long noncoding RNAs (lncRNAs) are indicated to involve in the development of keloid. However, the role of lncRNA LINC01615 in regulating keloid development and the underlying mechanism are still unknown.
Xiaoyu Zhang, Yingying Xu, Kenji Yamaguchi, Jinping Hu, Lianbo Zhang, Jianfeng Wang, Jifeng Tian, Wanying Chen   +7 more
openaire   +1 more source

Novel Clinical Insights into the Pathogenesis of Posttraumatic Elbow Stiffness: An Expression Profile Analysis of Contracted Joint Capsule in Human [PDF]

Journal of Inflammation Research
Nan Liu,1 Jinlei Dong,1 Lianxin Li,1 Jiajun Xu,1 Changhao Yang,1 Zhanchuan Yu,2 Fanxiao Liu1 1Department of Shandong Trauma Center, Shandong Provincial Hospital affiliated to Shandong First Medical University, Jinan, Shandong, 250014, People’s Republic ...
Liu N, Dong J, Li L, Xu J, Yang C, Yu Z, Liu F   +6 more
doaj   +2 more sources