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Association Between miRNAs and the Diagnosis, Prognosis, and Recurrence of Patients with Meningioma: A Systematic Review. [PDF]

open access: yesCell Mol Neurobiol
Nieva Posso DA   +6 more
europepmc   +1 more source
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MiR-590-5p promotes cisplatin resistance via targeting hMSH2 in ovarian cancer

Molecular Biology Reports, 2023
The mechanisms of ovarian cancer generate chemotherapy resistance are still unclear. This study aimed to explore the role of microRNA (miR)-590-5p in regulating hMSH2 expression and cisplatin resistance in ovarian cancer.MiR-590-5p was identified as a regulator of hMSH2 with miRDB database and Target Scan database.
Bing Li   +5 more
openaire   +2 more sources

MiR-590-5p inhibits pathological hypertrophy mediated heart failure by targeting RTN4

Journal of Molecular Histology, 2021
Heart failure (HF) is a rising epidemic and public health burden in modern society. It is of great need to find new biomarkers to ensure a timely diagnosis and to improve treatment and prognosis of the disease. The mouse model of HF was established by thoracic aortic constriction.
Ping, Fan   +7 more
openaire   +2 more sources

Chitosan/nano-hydroxyapatite/nano-zirconium dioxide scaffolds with miR-590-5p for bone regeneration

International Journal of Biological Macromolecules, 2018
Bone tissue engineering (BTE) relies on biocomposite scaffolds and bioactive molecules for bone regeneration. The present study was aimed to synthesize and characterize biocomposite scaffolds containing chitosan (CS), nano-hydroxyapatite (nHAp) and nano‑zirconium dioxide (nZrO2) along with microRNA (miRNA) for BTE applications.
G Devanand Venkatasubbu   +1 more
exaly   +3 more sources

MiR-590-5p, a density-sensitive microRNA, inhibits tumorigenesis by targeting YAP1 in colorectal cancer

Cancer Letters, 2017
YAP1, a transcription co-activator, mediates the biological functions of the Hippo pathway. YAP1 inactivation is involved in cell-cell contact inhibition. In various tumors, YAP1 is upregulated through multiple mechanisms, and it functions as an oncogene.
Chunlin Ou, Zhenqiang Sun, Wei-Tang Yuan
exaly   +3 more sources

MiR-590-5p alleviates intracerebral hemorrhage-induced brain injury through targeting Peli1 gene expression

Biochemical and Biophysical Research Communications, 2018
Intracerebral haemorrhage (ICH) is a common and devastating cerebrovascular disease with high morbidity and mortality, and its pathophysiological mechanisms were complex and still unclear. Increasing researches reported that microRNAs (miRNAs) played an important role in ICH-induced brain injury and microglial activation. In this study, we investigated
Qiang, Guo   +4 more
openaire   +2 more sources

MiR-590-5p-meidated LOX-1 upregulation promotes Angiotensin II-induced endothelial cell apoptosis

Biochemical and Biophysical Research Communications, 2016
Endothelial cell apoptosis contributes to cardiovascular diseases such as hypertension, atherosclerosis. MicroRNA regulates endothelial cell function but its role in endothelial cell apoptosis remains to be fully elucidated. This study aims to investigate the role of miR-590-5p in endothelial cell apoptosis and dissect the underlying mechanisms.Flow ...
Ping, Luo   +8 more
openaire   +2 more sources

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