Results 191 to 200 of about 5,835 (205)

CircPAG1 Inhibits the High Glucose-Induced Lens Epithelial Cell Injury by Sponging miR-630 and Upregulating EPHA2

Current Eye Research, 2021
Background: Circular RNAs (circRNAs) have been considered as vital regulators in the progression of human ocular diseases, including diabetic cataract (DC). This report was designed to research the biological role of circRNA phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (circPAG1) in high glucose (HG)-induced lens epithelial ...
Youyi, Yang, Qianqian, Li, Xin, Zhang, Gangfeng, Cui   +3 more
openaire   +2 more sources

CircDLG1 promotes malignant development of non-small cell lung cancer through regulation of the miR-630/CENPF axis

Strahlentherapie und Onkologie, 2022
Circular RNAs (circRNAs) have been reported to be crucial modulatory molecules in the etiology of non-small cell lung cancer (NSCLC). This study aimed to probe the precise role and mechanism of circRNA discs large MAGUK scaffold protein 1 (circDLG1) in the malignant progression of NSCLC.The abundances of circDLG1, miR-630, and centromere protein F ...
Yingying, Chen, Ying, Zhang
openaire   +2 more sources

CircMAP3K4 Suppresses H2O2-Induced Human Lens Epithelial Cell Injury by miR-630/ERCC6 Axis in Age-Related Cataract

Current Eye Research, 2023
Dysregulated circular RNAs (circRNAs) is involved in the pathogenesis of age-related cataract (ARC). Here, this study aimed to explore the function and mechanism of circMAP3K4 in ARC.Human lens epithelial cells were exposed to hydrogen peroxide (H2O2) for functional experiments.
Fenghua, Cui, Zhonghua, Sun, Xueyan, Zhang, Cuijuan, Liu   +3 more
openaire   +2 more sources

circMTDH.4/miR‐630/AEG‐1 axis participates in the regulation of proliferation, migration, invasion, chemoresistance, and radioresistance of NSCLC

Molecular Carcinogenesis, 2019
AbstractAstrocyte elevated gene‐1 (AEG‐1) plays a critical role in the development, progression, and metastasis of a variety of cancers, including non‐small–cell lung cancer (NSCLC). The objective of the current study is to unravel the upstream signaling of AEG‐1. A cohort of 28 NSCLC tissues and 30 normal tissues were collected.
Ying‐Hong Li, Chun‐Lin Xu, Chang‐Jun He, Hai‐Hong Pu, Jing‐Lei Liu, Yan Wang   +5 more
openaire   +2 more sources

Long noncoding RNA H19 regulates EZH2 expression by interacting with miR-630 and promotes cell invasion in nasopharyngeal carcinoma

Biochemical and Biophysical Research Communications, 2016
The long non-coding RNA (lncRNA) H19 has been recently shown to participate in the progression of cancer, including metastasis. However, the biological role of H19 and the underlying mechanisms mediating its functions in nasopharyngeal carcinoma (NPC) remain unclear.
Xudong, Li, Yan, Lin, Xi, Yang, Xiaoguang, Wu, Xiaoguang, He   +4 more
openaire   +2 more sources

Upregulation of miR-630 Induced by Oxidative Damage Resists Cell Migration Through Targeting ALCAM in Human Lens Epithelium Cells

Current Eye Research, 2019
Purpose: To investigate the role of miRNAs in regulating oxidative damage during cataract formation.Methods: Microarray analysis and gene expression profiling assay were used to separately evaluate the miRNAs and mRNAs profiles in normal human lens epithelium cell line HLE-B3 treated by H2O2.
Lin, Mei, Hong, Yan, Song, Wang, Chenjun, Guo, Xiaoliang, Zheng, Bo, Yan, Jing, Zhao, Angang, Yang   +7 more
openaire   +2 more sources

Analysis of miR-483-3p and miR-630 expression profile in pediatric adrenocortical tumors and the effect of their modulation on adrenal tumorigenesis in vitro

Molecular and Cellular Endocrinology
Pediatric adrenocortical tumors (ACT) are rare aggressive neoplasms with heterogeneous prognosis. MicroRNA (miRNA) signatures have been associated with cancer diagnosis, treatment response, and outcomes of several types of cancer. However, the role played by miRNAs in pediatric ACT has been poorly explored.
Carolina Alves Pereira Corrêa, Augusto Faria Andrade, Luciana Chain Veronez, Keteryne Rodrigues da Silva, Mirella Baroni, Veridiana Kill Suazo, Rosane de Paula Gomes Queiroz, Régia Caroline Peixoto Lira, Pablo Shimaoka Chagas, Silvia Regina Brandalise, José Andres Yunes, Carlos Augusto Fernandes Molina, Sonir Roberto Rauber Antonini, Elvis Terci Valera, Luiz Gonzaga Tone, Carlos Alberto Scrideli   +15 more
openaire   +2 more sources

Acovenoside A as a novel therapeutic approach to boost taxol and carboplatin apoptotic and antiproliferative activities in NSCLC: Interplay of miR-630/miR-181a and apoptosis genes

Bioorganic Chemistry, 2023
Mai A Abd-Elmawla, Omar Sabry, Nora M Aborehab   +2 more
exaly  

Silencing of circARHGAP12 inhibits the progression of atherosclerosis via miR‐630/EZH2/TIMP2 signal axis

Journal of Cellular Physiology, 2022
Xiubo Lu, Xiubo Lu
exaly  

Faculty Opinions recommendation of miR-181a and miR-630 regulate cisplatin-induced cancer cell death.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2010
Patrice Morin, Neetu Dahiya
openaire   +1 more source