Results 191 to 200 of about 214,976 (242)
AND‐Logic‐Gated Aptamer Switch for Precise Targeting and Regulation of RNA G‐Quadruplexes
Angewandte Chemie, EarlyView.An AND‐logic‐gated aptamer switch enables tumor‐selective activation of RNA G‐quadruplex (rG4)‐targeting function. By combining cell‐surface recognition and intracellular redox sensing, the system achieves precise regulation of disease‐relevant RNA structures exclusively in tumor cells, with minimal off‐target effects in normal cells, offering a ...
Dan Wang, Ying Feng, Chun Kit Kwok
wiley +2 more sources
Advanced NanoBiomed Research, EarlyView.We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.Constructing atomically coupled W–O–Ru interfacial units on RuO2 triggers a dynamic strain evolution during the oxygen evolution reaction. An initial tensile strain secures structural stability, while a self‐adjusting transition to interfacial compression optimizes catalytic activity.
Yi Guan +7 more
wiley +2 more sources
Evaluation of the Cytotoxicity of Biochar Aqueous Extract in Caco-2 Cells: Time-Dependent Regulation of Apoptosis, Associated with miRNA Modulation. [PDF]
MoleculesAmin S +7 more
europepmc +1 more source
Steuerung der Rotation eines Guanidiniumkations durch Kation‐π‐Wechselwirkungen
Angewandte Chemie, EarlyView.Ein Lanthanid‐π‐Container wurde für die Bindung eines Guanidiniumkations in dessen aromatischer Kavität mittels Kation‐π‐Wechselwirkungen verwendet. Röntgenkristallographie und Festkörper‐NMR‐Spektroskopie bei schneller Rotation um den magischen Winkel wurden verwendet, um die zugrundeliegenden Wirt‐Gast‐Interaktionen zu untersuchen.
Hannah Busch +12 more
wiley +1 more source
Angewandte Chemie, EarlyView.Red‐emissive carbon dots (R‐CDs) exhibiting aggregation‐induced emission (AIE) and aggregation‐caused quenching (ACQ) effects are synthesized from citric acid and urea. They display weak blue fluorescence in water but strong red emission in DMF due to aggregation.
Jiafeng Wan +11 more
wiley +2 more sources
Advances in BODIPY Derivatives for Antibacterial Phototherapy
Angewandte Chemie, EarlyView.This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv +9 more
wiley +2 more sources
Angewandte Chemie, EarlyView.Octahedral (DFPD)6CdCl8:10%Sb and tetrahedral (DFPD)2CdCl4·H2O:5%Sb exhibit distinct luminescence dictated by coordination geometry. Solvent‐induced reversible phase transformation enables dynamic switching between yellow and deep‐orange emission. Combined experimental and computational studies elucidate the luminescence mechanisms, and the reversible ...
Zhe Tang +7 more
wiley +2 more sources