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KNOCKDOWN OF CIRC_0001379 ATTENUATES HYPOXIA/REOXYGENATION-INDUCED CARDIOMYOCYTE APOPTOSIS AND INFLAMMATORY RESPONSE BY MIR-98-5P/SOX6 AXIS

Shock, 2023
ABSTRACT Background: Aberrant expression of circular RNAs (circRNAs) has been revealed to have crucial roles in the pathological processes of cardiovascular disease. Here, this study aimed to investigate the role and mechanism of circ_0001379 in hypoxia/reoxygenation (H/R)-induced cardiomyocyte injury to explore ...
Kun, Wang   +3 more
openaire   +2 more sources

miR-98-5p Acts as a Target for Alzheimer’s Disease by Regulating Aβ Production Through Modulating SNX6 Expression

Journal of Molecular Neuroscience, 2016
Accumulation of amyloid β-peptide (Aβ) in the brain of Alzheimer disease (AD) patients is believed to be the main pathological feature of the disease. Meanwhile, miR-98-5p dysregulation was found in AD. However, whether miR-98-5p is involved in the accumulation of Aβ in AD, the underlying molecule mechanism remains unclear.
Qiushi, Li   +4 more
openaire   +2 more sources

NEAT1/hsa‐mir‐98‐5p/MAPK6 axis is involved in non–small‐cell lung cancer development

Journal of Cellular Biochemistry, 2018
AbstractLong noncoding RNAs (lncRNAs) or microRNAs belong to the two most important noncoding RNAs and they are involved in a lot of cancers, including non–small‐cell lung cancer (NSCLC). Therefore, currently, we focused on the biological and clinical significance of lncRNA nuclear enriched abundant transcript 1 (NEAT1) and hsa‐mir‐98‐5p in NSCLC.
Feima Wu   +4 more
openaire   +2 more sources

LncRNA TTTY15 knockdown alleviates H2O2-stimulated myocardial cell injury by regulating the miR-98-5p/CRP pathway

Molecular and Cellular Biochemistry, 2020
Acute myocardial infarction (AMI) can lead to myocardial injury, and long non-coding RNA (lncRNA) has been found to play an important regulatory role in the process of myocardial injury. However, the role and potential mechanisms of lncRNA testis-specific transcript Y-linked 15 (TTTY15) in AMI-induced myocardial injury has not been fully elucidated ...
Rufei Ma   +5 more
openaire   +2 more sources

MiR‐98‐5p promotes ischemia/reperfusion‐induced microvascular dysfunction by targeting NGF and is a potential biomarker for microvascular reperfusion

Microcirculation, 2020
AbstractObjectiveThis study examined the correlation between serum miR‐98‐5p levels and indices of microvascular reperfusion in patients undergoing primary percutaneous coronary intervention (pPCI) after ST‐segment elevation myocardial infarction (STEMI).
Yisen Hu   +4 more
openaire   +2 more sources

[miR-98-5p promotes apoptosis and inhibits migration by reducing the level of STAT3 in A549 cells].

Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2019
Objective To explore the effects of microRNA-98-5p (miR-98-5p) on the growth of lung cancer A549 cells and its mechanism. Methods The expression of miR-98-5p in the normal human bronchial epithelial (HBE) cell line and NSCLC cell lines (A549, H1299 and H460) was detected using real-time quantitative PCR.
Huilin, Liu, Min, Wei, Guoxia, Wang
openaire   +1 more source

Evaluation of miR-98-5P and GAB2 gene expression in endometriosis

Gene Reports
Javad Fazeli   +5 more
openaire   +1 more source

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