Results 41 to 50 of about 6,077 (292)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

After Wildfires and Rewetting: Results of 15+ Years’ Monitoring of Vegetation and Environmental Factors in Cutover Peatland

Diversity, 2022
On examples of n × 100 m2 permanent plots laid in 2005 on peatlands disturbed by quarrying and milling peat extraction in Meshchera National Park (central European Russia), changes in vegetation cover and environmental factors during self-revegetation ...
Anna Vozbrannaya, Vladimir Antipin, Andrey Sirin   +2 more
doaj   +1 more source

A phytosociological study of soligenous mires and springs in the north Pennines [PDF]

, 1993
Not ...
Duckworth, Jennifer C.
core  

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Plant Organic Matter in Palsa and Khasyrei Type Mires: Direct Observations in West Siberian Sub-Arctic

Atmosphere, 2021
This article presents the first results of long-term direct measurements of a few major components of carbon cycle in permafrost mire landforms in the sub-Arctic region of Western Siberia, Russia. It reveals the main features of geographical distribution
Natalia P. Kosykh, Nina P. Mironycheva-Tokareva, Evgeniya K. Vishnyakova, Natalia G. Koronatova, Vera A. Stepanova, Larisa G. Kolesnychenko, Aldynai O. Khovalyg, Anna M. Peregon   +7 more
doaj   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Intricate Spatial Soil Carbon Distribution in Four Pyrenean Mires [PDF]

Alpine mires in the Pyrenees are remarkable ecosystems for the singularity of their plant communities and for their occurrence at a southern distribution limit.
Carrillo, Empar, Pladevall Izard, Eulàlia, Pérez Haase, Aaron, Miyasiro-López, María G., Martínez-Amigo, Violeta, Ninot i Sugrañes, Josep Maria   +5 more
core   +1 more source

Ecohydrological Features of Some Contrasting Mires in Tierra Del Fuego, Argentina [PDF]

Mires and Peat, 2010
In November 2005, Tierra del Fuego (Argentina) hosted the biennial conference and field excursion of the International Mire Conservation Group (IMCG). The group considered the vegetation, hydrology, peat stratigraphy and possible management options for ...
A. Grootjans, R. Iturraspe, A. Lanting, C. Fritz, H. Joosten   +4 more
doaj   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Methods for determining peat humification and for quantifying peat bulk density, organic matter and carbon content for palaeostudies of climate and peatland carbon dynamics [PDF]

Mires and Peat, 2011
Quantitative palaeostudies of climate change and carbon dynamics are reliant on precise and accurate laboratory measurements. Here we present laboratory protocols for the colorimetric determination of peat humification and for bulk density and organic ...
F.M. Chambers, D.W. Beilman, Z. Yu
doaj