Results 131 to 140 of about 447,640 (362)

RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage

Annals of the Rheumatic Diseases, 2018
Objective To uncover the microRNA (miRNA) interactome of the osteoarthritis (OA) pathophysiological process in the cartilage. Methods We performed RNA sequencing in 130 samples (n=35 and n=30 pairs for messenger RNA (mRNA) and miRNA, respectively) on ...
Rodrigo Coutinho de Almeida, Yolande F M Ramos, A. Mahfouz, W. D. den Hollander, N. Lakenberg, E. Houtman, M. van Hoolwerff, H. Suchiman, A. Rodríguez Ruiz, P. Slagboom, H. Mei, S. Kiełbasa, R. Nelissen, M. Reinders, I. Meulenbelt   +14 more
semanticscholar   +1 more source

Rational Design of Optical Single‐Walled Carbon Nanotube‐Based Nanosensors with Biological Recognition Elements

Advanced Sensor Research, EarlyView.
This Review focuses on assessing and providing perspective on the field of rationally‐designed optical sensors constructed with single‐walled carbon nanotubes. The literature is reviewed and evaluated for SWCNT‐based sensors constructed with biomolecular recognition elements, including proteins, peptides, and oligonucleotides, as well as their methods ...
Amelia K. Ryan, Atara Israel, Maria Celina Stefoni, Catarina Ferraz, Ryan M. Williams   +4 more
wiley   +1 more source

Genetic and epigenetic sex-specific adaptations to endurance exercise

Epigenetics, 2019
In recent years, the interest in personalised interventions such as medicine, nutrition, and exercise is rapidly rising to maximize health outcomes and ensure the most appropriate treatments.
Shanie Landen, Sarah Voisin, Jeffrey M Craig, Sean L. McGee, Séverine Lamon, Nir Eynon   +5 more
doaj   +1 more source

Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

Scientific Reports, 2017
The pathogenesis of osteoarthritis (OA) is poorly understood, and therapeutic approaches are limited to preventing progression of the disease. Recent studies have shown that exosomes play a vital role in cell-to-cell communication, and pathogenesis of ...
R. Kolhe, M. Hunter, Siyang Liu, R. Jadeja, C. Pundkar, A. Mondal, B. Mendhe, M. Drewry, M. Rojiani, Yutao Liu, C. Isales, R. Guldberg, M. Hamrick, S. Fulzele   +13 more
semanticscholar   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

Advanced Sensor Research, EarlyView.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

MicroRNA (miRNA) PROFILING IN PROSTATE CANCER CARCINOGENESIS: EXPLORATORY RESEARCH

Jurnal Kedokteran dan Kesehatan
Future research will continue to be carried out in terms of looking for molecular markers involved in the early processes of carcinogenesis, metastasis and therapeutic targets in prostate cancer patients.
Maria Ulfa, Krisna Murti
doaj   +1 more source

miRNA-132/212 Gene-Deletion Aggravates the Effect of Oxygen-Glucose Deprivation on Synaptic Functions in the Female Mouse Hippocampus [PDF]

, 2021
Daniel Bormann, Tamara Stojanovic, Ana Cicvaric, Gabor Jorrid Schuld, Maureen Cabatic, Hendrik Jan Ankersmit, Francisco J. Monje   +6 more
openalex   +1 more source

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

Advanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han, Dae‐Seong Lee, Su‐Won Jeong, Ji‐Hyun Yun, Seomin Kang, Seoyoung Jang, EunAh Lee, Ju Hye Baek, Che Ok Jeon, Jin‐Woo Bae   +9 more
wiley   +1 more source

Serum miRNA-203 Expression in Patients with Coronary Artery Disease and Abdominal Obesity [PDF]

, 2019
E. A. Polyakova, M.I. Zaraisky, О. D. Belyaeva, О. А. Беркович, E. Baranova, Е. V. Shlyakhto, E.V. Shlyakhto   +6 more
openalex   +1 more source