Results 241 to 250 of about 563,981 (384)

Annotating and quantifying pri-miRNA transcripts using RNA-Seq data of wild type and serrate-1 globular stage embryos of Arabidopsis thaliana

, 2017
Daniel Lepe-Soltero, Alma Armenta-Medina, Daoquan Xiang, Raju Datla, C. Stewart Gillmor, Cei Abreu‐Goodger   +5 more
openalex   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

miRNAs in Glomerular Diseases: From Pathogenic Insight to Therapeutic Potential: A Narrative Review. [PDF]

Cells
Apetrii M, Costache AD, Costache Enache II, Voroneanu L, Covic AS, Kanbay M, Scripcariu DV, Covic A.   +7 more
europepmc   +1 more source

An integrated expression atlas of miRNAs and their promoters in human and mouse

Nature Biotechnology, 2017
Derek de Rie, I. Abugessaisa, T. Alam, E. Arner, P. Arner, Haitham Ashoor, G. Åström, M. Babina, N. Bertin, A. M. Burroughs, A. Carlisle, C. Daub, M. Detmar, Ruslan Deviatiiarov, A. Fort, C. Gebhard, D. Goldowitz, S. Guhl, Thomas J. Ha, J. Harshbarger, A. Hasegawa, K. Hashimoto, M. Herlyn, P. Heutink, Kelly J. Hitchens, C. Hon, E. Huang, Y. Ishizu, C. Kai, T. Kasukawa, P. Klinken, T. Lassmann, C. Lecellier, Weonju Lee, M. Lizio, V. Makeev, Anthony Mathelier, Y. Medvedeva, Niklas Mejhert, C. Mungall, Shohei Noma, M. Ohshima, M. Okada‐Hatakeyama, H. Persson, P. Rizzu, Filip Roudnicky, P. Sætrom, Hiroki Sato, Jessica Severin, Jay W. Shin, R. Swoboda, H. Tarui, H. Toyoda, Kristoffer Vitting-Seerup, Louise N. Winteringham, Y. Yamaguchi, K. Yasuzawa, M. Yoneda, N. Yumoto, S. Zabierowski, Peter G. Zhang, C. Wells, K. Summers, H. Kawaji, A. Sandelin, M. Rehli, Y. Hayashizaki, Piero Carninci, A. Forrest, M. D. de Hoon   +69 more
semanticscholar   +1 more source

TGFβ1 Activates Lnc‐APUE to Promote Tumor Metastasis via the Alu Element‐Driven STAU1‐Mediated Decay of CDH1 mRNA

Advanced Science, EarlyView.
We delineate a TGFβ1/SMAD/lnc‐APUE/E‐cadherin axis wherein TGFβ1 signaling activates lnc‐APUE; lnc‐APUE subsequently downregulates E‐cadherin expression via Alu element‐driven STAU1‐mediated decay of CDH1 mRNA, thereby promoting tumor metastasis. Our findings reveal a novel regulatory function for lnc‐APUE within the SMD pathway, elucidate a distinct ...
Song‐Yang Li, Jia‐Hui Huang, Jin‐E Yang, Yi‐Hang Li, Juan‐Zhen Hong, Ting‐Ting Wang, Ying‐Lei Chi, Meng‐Zhi Wu, Wei Wang, Ying Zhu, Shi‐Mei Zhuang   +10 more
wiley   +1 more source

MicroRNA dysregulation in cow's jejunum, jejunal lymph node, and caecal Peyer's patch during Mycobacterium avium subsp. paratuberculosis infection. [PDF]

BMC Genomics
Wang M, Bissonnette N, Dudemaine PL, Ibeagha-Awemu EM.   +3 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

Exosome and miRNA Content Engagement in the Physical Exercise Response: What Is Known to Date in Atheltic Horses? [PDF]

Int J Mol Sci
Sisia G, Giudice E, Attanzio A, Briglia M, Piccione G, Trunfio C, Arfuso F.   +6 more
europepmc   +1 more source

Functional delivery of viral miRNAs via exosomes

Proceedings of the National Academy of Sciences of the United States of America, 2010
D. Pegtel, Katherine Cosmopoulos, D. Thorley-Lawson, Monique A J van Eijndhoven, Erik S. Hopmans, Jelle L Lindenberg, T. D. de Gruijl, T. Würdinger, Jaap M Middeldorp   +8 more
semanticscholar   +1 more source