Results 261 to 270 of about 365,273 (304)
Some of the next articles are maybe not open access.
Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma
Clinical Neurology and Neurosurgery, 2017Meningiomas are among the most common intracranial tumors, accounting for 30% of all tumors of the central nervous system. Recent studies analyzing microRNA (miRNA) profiles and functions in cancer have provided valuable information about the molecular pathogenesis of several tumor types, including glioblastoma multiforme (GBM), hepatocellular ...
Katar, Salim +8 more
openaire +3 more sources
2023
MicroRNAs (miRNAs) are small, noncoding RNAs that regulate gene expression. They play an important role in many biological processes including human diseases. However, miRNAs are challenging to detect due to their short sequence length and low copy number.
Afrah, Bawazeer, David C, Prince
openaire +2 more sources
MicroRNAs (miRNAs) are small, noncoding RNAs that regulate gene expression. They play an important role in many biological processes including human diseases. However, miRNAs are challenging to detect due to their short sequence length and low copy number.
Afrah, Bawazeer, David C, Prince
openaire +2 more sources
Inflammation, 2016
Hidradenitis suppurativa (HS) has been associated with marked inflammatory perturbation. The mechanisms regulating the inflammatory network remain elusive. microRNAs (miRNAs) have been described as gene regulators of inflammation. We evaluated the messenger RNA (mRNA) expression levels of six selected inflammation-related miRNAs in lesional and ...
S. Hessam +4 more
openaire +2 more sources
Hidradenitis suppurativa (HS) has been associated with marked inflammatory perturbation. The mechanisms regulating the inflammatory network remain elusive. microRNAs (miRNAs) have been described as gene regulators of inflammation. We evaluated the messenger RNA (mRNA) expression levels of six selected inflammation-related miRNAs in lesional and ...
S. Hessam +4 more
openaire +2 more sources
International Journal of Neuroscience, 2009
Micro RNAs (miRNAs) are endogenous noncoding RNAs that are important for gene regulation. This review provides an overview of miRNA biogenesis and mechanism of action. The review focuses on studies relating to the spatial and temporal regulation of gene expression in neurons.
S, Trivedi, G, Ramakrishna
openaire +2 more sources
Micro RNAs (miRNAs) are endogenous noncoding RNAs that are important for gene regulation. This review provides an overview of miRNA biogenesis and mechanism of action. The review focuses on studies relating to the spatial and temporal regulation of gene expression in neurons.
S, Trivedi, G, Ramakrishna
openaire +2 more sources
2010
RNA editing by A-to-I modification is a widespread mechanism in complex organisms that leads to the posttranscriptional alteration of protein coding as well as noncoding sequences. MiRNA transcripts have been recognized as a major target for RNA editing enzymes, and single-nucleotide changes through editing can impact the biogenesis of mature miRNAs ...
Dylan E, Dupuis, Stefan, Maas
openaire +2 more sources
RNA editing by A-to-I modification is a widespread mechanism in complex organisms that leads to the posttranscriptional alteration of protein coding as well as noncoding sequences. MiRNA transcripts have been recognized as a major target for RNA editing enzymes, and single-nucleotide changes through editing can impact the biogenesis of mature miRNAs ...
Dylan E, Dupuis, Stefan, Maas
openaire +2 more sources
2011
Since 2004, more than 200 microRNAs (miRNAs) have been discovered in double-stranded DNA viruses, mainly herpesviruses and polyomaviruses (Nucleic Acids Res 32:D109-D111, 2004). miRNAs are short 22 ± 3 nt RNA molecules that posttranscriptionally regulate gene expression by binding to 3'-untranslated regions (3'UTR) of target mRNAs, thereby inducing ...
Karlie, Plaisance-Bonstaff, Rolf, Renne
openaire +2 more sources
Since 2004, more than 200 microRNAs (miRNAs) have been discovered in double-stranded DNA viruses, mainly herpesviruses and polyomaviruses (Nucleic Acids Res 32:D109-D111, 2004). miRNAs are short 22 ± 3 nt RNA molecules that posttranscriptionally regulate gene expression by binding to 3'-untranslated regions (3'UTR) of target mRNAs, thereby inducing ...
Karlie, Plaisance-Bonstaff, Rolf, Renne
openaire +2 more sources
miRNA–miRNA crosstalk: from genomics to phenomics
Briefings in Bioinformatics, 2016The discovery of microRNA (miRNA)-miRNA crosstalk has greatly improved our understanding of complex gene regulatory networks in normal and disease-specific physiological conditions. Numerous approaches have been proposed for modeling miRNA-miRNA networks based on genomic sequences, miRNA-mRNA regulation, functional information and phenomics alone, or ...
Juan Xu 0001 +4 more
openaire +2 more sources
miRNAs on the move: miRNA biogenesis and the RNAi machinery
Current Opinion in Cell Biology, 2004Recent advances have led to a more detailed understanding of RNA interference and its role in microRNA biogenesis and function. Primary microRNA transcripts are processed by the RNaseIII nuclease, Drosha, and are exported from the nucleus by Exportin-5.
Elizabeth P, Murchison +1 more
openaire +2 more sources
An Overview of miRNA and miRNA Target Analysis Tools
2019microRNA molecules have been shown to play various significant roles in many physiological and pathophysiological processes in living organisms. The tremendous interest in these molecules has led to the significant development and constant release of a number of computational tools useful for basic as well as advanced miRNA-related analyses.
Anna, Lukasik, Piotr, Zielenkiewicz
openaire +2 more sources
miRNAs Targeting and Targeting miRNAs
2009With the recent advance of research into microRNAs (miRNAs), this category of endogenous noncoding small ribonucleic acids (19–25 nts in length) has rapidly emerged as one of the central regulators of expression of an extensive repertoire of genes. MiRNAs are an abundant RNA species constituting >2% of the predicted human genes (> 1,000 genes), which ...
openaire +1 more source