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Expression of miRNA-21, miRNA-107, miRNA-137 and miRNA-29b in meningioma
Clinical Neurology and Neurosurgery, 2017Meningiomas are among the most common intracranial tumors, accounting for 30% of all tumors of the central nervous system. Recent studies analyzing microRNA (miRNA) profiles and functions in cancer have provided valuable information about the molecular pathogenesis of several tumor types, including glioblastoma multiforme (GBM), hepatocellular ...
Katar, Salim +8 more
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2023
MicroRNAs (miRNAs) are small, noncoding RNAs that regulate gene expression. They play an important role in many biological processes including human diseases. However, miRNAs are challenging to detect due to their short sequence length and low copy number.
Afrah, Bawazeer, David C, Prince
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MicroRNAs (miRNAs) are small, noncoding RNAs that regulate gene expression. They play an important role in many biological processes including human diseases. However, miRNAs are challenging to detect due to their short sequence length and low copy number.
Afrah, Bawazeer, David C, Prince
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Inflammation, 2016
Hidradenitis suppurativa (HS) has been associated with marked inflammatory perturbation. The mechanisms regulating the inflammatory network remain elusive. microRNAs (miRNAs) have been described as gene regulators of inflammation. We evaluated the messenger RNA (mRNA) expression levels of six selected inflammation-related miRNAs in lesional and ...
S. Hessam +4 more
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Hidradenitis suppurativa (HS) has been associated with marked inflammatory perturbation. The mechanisms regulating the inflammatory network remain elusive. microRNAs (miRNAs) have been described as gene regulators of inflammation. We evaluated the messenger RNA (mRNA) expression levels of six selected inflammation-related miRNAs in lesional and ...
S. Hessam +4 more
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International Journal of Neuroscience, 2009
Micro RNAs (miRNAs) are endogenous noncoding RNAs that are important for gene regulation. This review provides an overview of miRNA biogenesis and mechanism of action. The review focuses on studies relating to the spatial and temporal regulation of gene expression in neurons.
S, Trivedi, G, Ramakrishna
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Micro RNAs (miRNAs) are endogenous noncoding RNAs that are important for gene regulation. This review provides an overview of miRNA biogenesis and mechanism of action. The review focuses on studies relating to the spatial and temporal regulation of gene expression in neurons.
S, Trivedi, G, Ramakrishna
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2010
RNA editing by A-to-I modification is a widespread mechanism in complex organisms that leads to the posttranscriptional alteration of protein coding as well as noncoding sequences. MiRNA transcripts have been recognized as a major target for RNA editing enzymes, and single-nucleotide changes through editing can impact the biogenesis of mature miRNAs ...
Dylan E, Dupuis, Stefan, Maas
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RNA editing by A-to-I modification is a widespread mechanism in complex organisms that leads to the posttranscriptional alteration of protein coding as well as noncoding sequences. MiRNA transcripts have been recognized as a major target for RNA editing enzymes, and single-nucleotide changes through editing can impact the biogenesis of mature miRNAs ...
Dylan E, Dupuis, Stefan, Maas
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2011
Since 2004, more than 200 microRNAs (miRNAs) have been discovered in double-stranded DNA viruses, mainly herpesviruses and polyomaviruses (Nucleic Acids Res 32:D109-D111, 2004). miRNAs are short 22 ± 3 nt RNA molecules that posttranscriptionally regulate gene expression by binding to 3'-untranslated regions (3'UTR) of target mRNAs, thereby inducing ...
Karlie, Plaisance-Bonstaff, Rolf, Renne
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Since 2004, more than 200 microRNAs (miRNAs) have been discovered in double-stranded DNA viruses, mainly herpesviruses and polyomaviruses (Nucleic Acids Res 32:D109-D111, 2004). miRNAs are short 22 ± 3 nt RNA molecules that posttranscriptionally regulate gene expression by binding to 3'-untranslated regions (3'UTR) of target mRNAs, thereby inducing ...
Karlie, Plaisance-Bonstaff, Rolf, Renne
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miRNA–miRNA crosstalk: from genomics to phenomics
Briefings in Bioinformatics, 2016The discovery of microRNA (miRNA)-miRNA crosstalk has greatly improved our understanding of complex gene regulatory networks in normal and disease-specific physiological conditions. Numerous approaches have been proposed for modeling miRNA-miRNA networks based on genomic sequences, miRNA-mRNA regulation, functional information and phenomics alone, or ...
Juan Xu 0001 +4 more
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