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An Overview of miRNA and miRNA Target Analysis Tools
2019microRNA molecules have been shown to play various significant roles in many physiological and pathophysiological processes in living organisms. The tremendous interest in these molecules has led to the significant development and constant release of a number of computational tools useful for basic as well as advanced miRNA-related analyses.
Anna, Lukasik, Piotr, Zielenkiewicz
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miRNAs on the move: miRNA biogenesis and the RNAi machinery
Current Opinion in Cell Biology, 2004Recent advances have led to a more detailed understanding of RNA interference and its role in microRNA biogenesis and function. Primary microRNA transcripts are processed by the RNaseIII nuclease, Drosha, and are exported from the nucleus by Exportin-5.
Elizabeth P, Murchison +1 more
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miRNAs Targeting and Targeting miRNAs
2009With the recent advance of research into microRNAs (miRNAs), this category of endogenous noncoding small ribonucleic acids (19–25 nts in length) has rapidly emerged as one of the central regulators of expression of an extensive repertoire of genes. MiRNAs are an abundant RNA species constituting >2% of the predicted human genes (> 1,000 genes), which ...
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miRNAs, cancer, and unconventional miRNA functions
Bulletin of Biotechnology, 2023MicroRNAs are non-protein-coding RNA molecules that control and fine-tune gene expression at the post-transcriptional level by negatively regulating their target genes. MicroRNAs mature into 22-nucleotide-long RNA transcripts that negatively regulate gene expression by inducing either inhibition of translation or degradation of mRNAs.
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Trends in Biochemical Sciences, 2008
The epidermis and its appendages provide organisms with protection from the environment, keeping pathogens out and preventing the loss of essential body fluids. To perform both functions, the skin has elaborated a complex differentiation process known as cornification.
Aberdam, D +3 more
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The epidermis and its appendages provide organisms with protection from the environment, keeping pathogens out and preventing the loss of essential body fluids. To perform both functions, the skin has elaborated a complex differentiation process known as cornification.
Aberdam, D +3 more
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American Journal of Clinical Pathology, 2007
MicroRNAs (miRNAs) can be defined as small, noncoding sets of 19 to 24 nucleotides that have been associated with messenger RNA expression. miRNAs are members of a class of small regulatory RNAs that includes small interfering RNAs (siRNAs). miRNAs regulate the expression of downstream gene targets, including transcription factors, oncogenes, and tumor
Jeffrey S, Ross +2 more
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MicroRNAs (miRNAs) can be defined as small, noncoding sets of 19 to 24 nucleotides that have been associated with messenger RNA expression. miRNAs are members of a class of small regulatory RNAs that includes small interfering RNAs (siRNAs). miRNAs regulate the expression of downstream gene targets, including transcription factors, oncogenes, and tumor
Jeffrey S, Ross +2 more
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An Overview of miRNA and miRNA Target Analysis Tools
MicroRNA molecules have been shown to play various significant roles in many physiological and pathophysiological processes in living organisms. The tremendous interest in these molecules has led to the significant development and constant release of a number of computational tools useful for basic as well as advanced miRNA-related analyses.Aizhan, Rakhmetullina +2 more
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Role of sex‐biased miRNAs in teleosts – a review
Reviews in Aquaculture, 2021Manisha Priyam +2 more
exaly
NTP4 modulates miRNA accumulation via asymmetric modification of miRNA/miRNA* duplex
Science China Life Sciences, 2020Wenwen, Kong +7 more
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