Results 41 to 50 of about 24,831 (136)

Models of Oral Epithelial Dysplasia: A Systematic Review and Temporal Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral squamous cell carcinoma (OSCC) is the most common malignancy of the head and neck, associated with substantial morbidity and mortality worldwide. Oral epithelial dysplasia (OED) can precede OSCC, offering a critical window for preventive and therapeutic intervention.
Zilefac Brian Ngokwe, Satutya Wicaksono, Michael McCullough, Antonio Celentano, Tami Yap   +4 more
wiley   +1 more source

MicroRNA Expression Profiling of Bone Marrow–Derived Proangiogenic Cells (PACs) in a Mouse Model of Hindlimb Ischemia: Modulation by Classical Cardiovascular Risk Factors

Frontiers in Genetics, 2020
BackgroundClassical cardiovascular risk factors (CRFs) are associated with impaired angiogenic activities of bone marrow–derived proangiogenic cells (PACs) related to peripheral artery diseases (PADs) and ischemia-induced neovascularization.
Michel Desjarlais, Michel Desjarlais, Sylvie Dussault, José Carlos Rivera, José Carlos Rivera, Sylvain Chemtob, Sylvain Chemtob, Alain Rivard   +7 more
doaj   +1 more source

Mid‐infrared spectroscopy applied to a multi‐level cave system (Montmaurin, SW France): An innovative method for assessing sediment provenance

Sedimentology, EarlyView.
ABSTRACT Deciphering sediment provenance is essential to understand depositional patterns and dynamics. This question is particularly important in archaeological contexts to constrain the sedimentological history of unearthed material—an information critically needed, for example, to estimate the age of the deposits—or to apprehend sediment movement ...
Fuchs Coraline, Rambeau Claire, Ertlen Damien, Rixhon Gilles, Perrenoud Christian, Ponche Jean‐Luc, Trautmann Martine, Benarioumlil Sylvain, Vialet Amélie   +8 more
wiley   +1 more source

Coronary Artery-Bypass-Graft Surgery Increases the Plasma Concentration of Exosomes Carrying a Cargo of Cardiac MicroRNAs: An Example of Exosome Trafficking Out of the Human Heart with Potential for Cardiac Biomarker Discovery.

PLoS ONE, 2016
IntroductionExosome nanoparticles carry a composite cargo, including microRNAs (miRs). Cultured cardiovascular cells release miR-containing exosomes. The exosomal trafficking of miRNAs from the heart is largely unexplored.
Costanza Emanueli, Andrew I U Shearn, Abas Laftah, Francesca Fiorentino, Barnaby C Reeves, Cristina Beltrami, Andrew Mumford, Aled Clayton, Mark Gurney, Saran Shantikumar, Gianni D Angelini   +10 more
doaj   +1 more source

MicroRNAs regulate several functions of normal tissues and malignancies

Taiwanese Journal of Obstetrics & Gynecology, 2013
MicroRNAs (miRNAs, miRs) are a cluster of naturally occurring small non-coding RNA molecules of 19–24 nucleotides in length. miRs control gene expression post-transcriptionally by binding to a specific site at the 3′-UTR of target mRNA, which results in ...
Kuo-Chang Wen, Pi-Ling Sung, Ming-Shyen Yen, Chi-Mu Chuang, Wen-Shiung Liou, Peng-Hui Wang   +5 more
doaj   +1 more source

miRNA Alterations Elicit Pathways Involved in Memory Decline and Synaptic Function in the Hippocampus of Aged Tg4-42 Mice

Frontiers in Neuroscience, 2020
The transcriptome of non-coding RNA (ncRNA) species is increasingly focused in Alzheimer’s disease (AD) research. NcRNAs comprise, among others, transfer RNAs, long non-coding RNAs and microRNAs (miRs), each with their own specific biological function ...
Yvonne Bouter, Tim Kacprowski, Fanny Rößler, Lars R. Jensen, Andreas W. Kuss, Thomas A. Bayer   +5 more
doaj   +1 more source

Immune Evasion of Helicobacter pylori and Extra‐Gastric Cancer Risk

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1722-1742, June 2026.
ABSTRACT Helicobacter pylori (H. pylori) is a group 1 gastric carcinogen that plays a significant role in extra‐gastric digestive system cancers. H. pylori disrupts host cell homeostasis through expression of virulence factors leading to immune evasion as well as persistent gastric mucosal colonization. H. pylori infection has been shown to play a role
Evren Doruk Engin, Ayse Basak Engin, Atilla Engin   +2 more
wiley   +1 more source

Gallic Acid‐Responsive microRNAs Reprogram Lignification During Drought Acclimation Process in Spearmint

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4263-4281, June 2026.
ABSTRACT Mentha spicata L. (spearmint) is a high‐value aromatic and medicinal species, whose productivity is strongly affected by water deficit. Nevertheless, the molecular mechanisms underlying drought acclimation in this mint remain largely unexplored. Thus, here, we investigated the microRNA‐mediated regulatory processes triggered in M.
Alessia D'Agostino, Gabriele Di Marco, Gerardo Pepe, Adelaide Teofani, Chiara Pontecorvi, Manuela Helmer‐Citterich, Antonella Canini, Angelo Gismondi   +7 more
wiley   +1 more source

Preservation of Extracellular Vesicle Integrity and Cargo Using Spiral Microfluidic Chip‐Based Separation

Advanced Materials Technologies, Volume 11, Issue 9, 6 May 2026.
A spiral microfluidic chip is compared with ultrafiltration for the separation of extracellular vesicles (EVs). The method preserves miRNA cargo and membrane integrity more effectively, resulting in intact vesicle morphology and consistent surface biomarker expression.
Huiseop Lee, Sehyeon Kim, Dasom Kong, Hye‐min Park, Hyun‐Ji Park, Jinsik Kim   +5 more
wiley   +1 more source

A simple high-throughput technology enables gain-of-function screening of human microRNAs

BioTechniques, 2013
MicroRNAs (miRs) regulate cellular processes by modulating gene expression. Although transcriptomic studies have identified numerous miRs differentially expressed in diseased versus normal cells, expression analysis alone cannot distinguish miRs driving ...
Wen-Chih Cheng, Tami J. Kingsbury, Sarah J. Wheelan, Curt I. Civin   +3 more
doaj   +1 more source