Results 31 to 40 of about 24,831 (136)

Circulating microRNAs are associated with variability in fasting blood glucose over 12-months and target pathways related to type 2 diabetes: A pilot study

Diabetes & Vascular Disease Research, 2021
Introduction MicroRNAs (miRs) may be important regulators of risk for type 2 diabetes (T2D). Circulating miRs may provide information about which individuals are at risk for T2D.
Elena Flowers, Isabel E Allen, Alka M Kanaya, Bradley E Aouizerat   +3 more
doaj   +1 more source

SAFE: a Mix‐and‐Read Assay for miRNA Detection in Extracellular Vesicles From Unprocessed Plasma Toward Clinical Disease Diagnosis

Small, EarlyView.
SAFE (Sonication‐Assisted liposome Fusion with EVs) is a rapid, mix‐and‐read assay that directly detects extracellular vesicle–encapsulated miRNAs from unprocessed plasma. By delivering molecular beacons into EVs via sonication‐driven liposome fusion, the method enables intravesicular hybridization with minimal background, providing quantitative ...
Subhra Sulipta Jena, Soo Jin Kim, Hyeonha Jang, Lianhua Chi, Yunji Eom, Kyung‐Oh Doh, JaeJong Lee, Jun Seok Park, Junyeop Lee, Seonki Hong   +9 more
wiley   +1 more source

Management Of Irrigation Water and its Impact on Agriculture Productivity [PDF]

Revista Română de Statistică, 2013
On the inflow side canal water in the canal command area of Mirwah is mismanaged by irrigation officials and head-end and influential farmers. Farmers in Sindh generally and Khairpur particularly irrigate their land without scientific techniques and ...
Asad Raza Abidi
doaj  

miRNA Profiling of Cholesteatoma‐Derived Exosomes Reveals Exosomal miR‐223‐3p and miR‐142‐5p as Potential Biomarkers for Acquired Middle Ear Cholesteatoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives Acquired cholesteatoma is an abnormal and invasive growth of keratinized squamous epithelial cells in the middle ear. The study aims to explore the role of exosomal miRNAs in the pathogenesis of acquired cholesteatoma and their potential in clinical application.
Qi Tang, Meng‐Yao Xie, Shu Wang, Zhi‐Yuan Wu, Zhi‐Jin Han, Chen Li, Shu‐Yi Wang, Yuan Cao, Yu‐Run Chen, Bin Wang, Ying‐Ying Shang, Xiao‐Wu Huang, Hua Yang   +12 more
wiley   +1 more source

Plasma exosome-derived microRNAs expression profiling and bioinformatics analysis under cross-talk between increased low-density lipoprotein cholesterol level and ATP-sensitive potassium channels variant rs1799858

Journal of Translational Medicine, 2020
Background Exosome-derived microRNAs (exo-miRs) as messengers play important roles, in the cross-talk between genetic [ATP-sensitive potassium channels (KATP) genetic variant rs1799858] and environmental [elevated serum low-density lipoprotein ...
Cheng Liu, Yanxian Lai, Songsong Ying, Junfang Zhan, Yan Shen   +4 more
doaj   +1 more source

Clinical Need and Research Investment for Liver Cancer in Australia

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Liver cancer incidence and mortality rates have been rising in comparison to other common cancers, but research funding has not been commensurate. ABSTRACT Aim This study aims to better understand factors driving the rising burden and costs of primary liver cancer (PLC) in Australia, identify key epidemiological trends, and ascertain investment in PLC ...
Romario Nguyen, Fatema Safri, Ankur Sharma, Jessica Howell, Stuart K. Roberts, Simone I. Strasser, Amany Zekry, Alan Wigg, Leon A. Adams, Michael Wallace, Golo Ahlenstiel, Eleonora Feletto, Karen Canfell, Tracey O'Brien, Jacob George, Liang Qiao   +15 more
wiley   +1 more source

Relationship Between PTBP1 and Pancreatic Cancer Based on microRNA and Behavior During TYMS‐Mediated Carcinogenesis

Cancer Science, EarlyView.
Corresponding Author and colleagues identify a pancreas‐enriched microRNA, miR‐216b‐5p, that suppresses PTBP1 and its downstream effector TYMS. Their findings reveal a novel miR‐216b‐5p/PTBP1/TYMS regulatory axis driving pancreatic cancer progression and establish PTBP1 as a central molecular regulator of tumor biology beyond its metabolic role ...
Shigenori Suzuki, Hiroaki Hase, Yosuke Inomata, Jun Arima, Kentaro Jingushi, Atsushi Tomioka, Nao Kawaguchi, Hiroki Hamamoto, Ryo Tanaka, Yoshiro Imai, Mitsuhiro Asakuma, Tomohito Tanaka, Kazutake Tsujikawa, Kohei Taniguchi, Sang‐Woong Lee   +14 more
wiley   +1 more source

Fault Prediction and Classification in Power Distribution Transformer Using Machine Learning

Sukkur IBA Journal of Emerging Technologies
This article used Random forest (RF) classifier, decision tree (DT) classifier, K-nearest neighbors (KNN) classifiers, extra tree (ET) classifier and extreme gradient boosting (XGB) classifier for fault prediction and classification in power ...
Zawar Ahmed Khan, Muhammad Amir Raza, Ramesh Kumar, Shakir Ali Soomro, Hizbullah Odho   +4 more
doaj   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

The FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia, Jiwang Tang, José C. Casas‐Martinez, Penglin Li, Maria Borja‐Gonzalez, Leo R Quinlan, Katarzyna Goljanek‐Whysall, Brian McDonagh   +7 more
wiley   +1 more source

Clinical Applications of MicroRNAs in Acute Myeloid Leukemia: A Mini-Review

Frontiers in Oncology, 2021
MicroRNAs (miRs) are short non-coding RNAs, typically 18-25 nucleotides in length, that are critically important, through their direct effects on target mRNAs, in a variety of cellular processes including cell differentiation, proliferation and survival.
Bhavana Bhatnagar, Ramiro Garzon, Ramiro Garzon   +2 more
doaj   +1 more source