Results 61 to 70 of about 22,504 (208)

Predicting Response to Pro‐Cognitive Interventions in Mood Disorders: A Systematic Review by the International Society for Bipolar Disorders Targeting Cognition Task Force

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Major depressive disorder (MDD) and bipolar disorder (BD) are often associated with persistent cognitive deficits that impair psychosocial functioning. While pro‐cognitive interventions show promise, trial findings are inconsistent, potentially due to baseline factors influencing treatment response.
Dimosthenis Tsapekos, Michail Kalfas, Johanna M. Schandorff, Caterina del Mar Bonnin, Christopher R. Bowie, Vicent Balanzá‐Martínez, Katherine E. Burdick, Andre F. Carvalho, Annemieke Dols, Katie Douglas, Peter Gallagher, Gregor Hasler, Lars V. Kessing, Hanne L. Kjærstad, Beny Lafer, Kathryn E. Lewandowski, Carlos López‐Jaramillo, Anabel Martinez‐Aran, Roger S. McIntyre, Richard J. Porter, Scot E. Purdon, Ayal Schaffer, Paul R. A. Stokes, Tomiki Sumiyoshi, Ivan J. Torres, Tamsyn E. Van Rheenen, Lakshmi N. Yatham, Jeff Zarp, Allan H. Young, Eduard Vieta, Kamilla W. Miskowiak   +30 more
wiley   +1 more source

Analysis of In Vitro Mirtazapine Metabolites in Human Liver Microsomes by LC-HRMS

Fayixue Zazhi
ObjectiveTo establish and optimize an in vitro incubation system with human liver microsomes and investigate the in vitro metabolites and possible metabolic pathways of mirtazapine.MethodsThree major metabolites of mirtazapine were selected to optimize ...
ZHANG Ying, ZHANG Wen-fang, XU Duo-qi, QIN Shi-yang, YANG Shi-yun, QIAO Jing   +5 more
doaj   +1 more source

Preliminary prediction of individual response to electroconvulsive therapy using whole-brain functional magnetic resonance imaging data. [PDF]

, 2020
Electroconvulsive therapy (ECT) works rapidly and has been widely used to treat depressive disorders (DEP). However, identifying biomarkers predictive of response to ECT remains a priority to individually tailor treatment and understand treatment ...
Abbott, Christopher C, Calhoun, Vince D, Espinoza, Randall, Jiang, Rongtao, Jones, Tom, Narr, Katherine L, Qi, Shile, Sui, Jing, Sun, Hailun, Upston, Joel, Wade, Benjamin Sc   +10 more
core   +1 more source

What is the therapeutic value of antidepressants in dementia? A narrative review [PDF]

, 2016
Objectives: Antidepressants are commonly used in dementia. Depression is a frequent and important co-morbidity in dementia and antidepressants are often used to treat depression and more widely.
Auchus, Badrakalimuthu, Bains, Ballard, Banerjee, Banerjee, Banerjee, Beeri, Bergh, Bharucha, Burke, Burns, Burns, Choe, Coen, Cohen-Mansfield, Deakin, Drye, Drye, Finkel, Finkel, Fuchs, Gaber, Gill, González-Salvador, Henry, Higgins, Karlsson, Katona, Klassen, Kørner, Lanctôt, Lebert, Leong, Levkovitz, Lyketsos, Lyketsos, Lyketsos, Lyketsos, Magai, Martin, Martinón-Torres, Mega, Mok, Moretti, Mowla, Munro, Munro, Nelson, Nyth, Nyth, Okura, Olafsson, Peters, Petracca, Petracca, Pitkala, Pollock, Pollock, Porsteinsson, Reekum, Reifler, Romeo, Rosenberg, Roth, Ryu, Schneider, Seitz, Sepehry, Sevush, Sink, Snowdon, Stern, Sultzer, Sultzer, Taragano, Tariot, Tariot, Teranishi, Teri, Teri, Thompson, Vasconcelos Cunha, Weintraub, Wetzels, Zarb, Zubenko, Zubenko, Zweig   +88 more
core   +1 more source

Psilocybin‐assisted psychotherapy for methamphetamine use disorder: A pilot open‐label safety and feasibility study

Addiction, EarlyView.
Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study.
Elizabeth Knock, Krista J. Siefried, Gill Bedi, Steven Albert, Richard O. Day, Nadine Ezard, Margaret Ross, Paul Liknaitzky, Jonathan Brett   +8 more
wiley   +1 more source

Effect of mirtazapine on weight and metabolic profile among psychiatric patients: A prospective, observational study from South India

Kerala Journal of Psychiatry
Background: Treatment with mirtazapine is reported to cause weight gain and adverse metabolic profile in several populations. Limited information is available regarding the metabolic adverse effects of mirtazapine in the Indian population.
Salma Nazim, S Asha, Mili Babu
doaj   +1 more source

Mirtazapine Reduces Adipocyte Hypertrophy and Increases Glucose Transporter Expression in Obese Mice

Animals, 2020
Metabolic syndrome is known to engender type 2 diabetes as well as some cardiac, cerebrovascular, and kidney diseases. Mirtazapine—an atypical second-generation antipsychotic drug with less severe side effects than atypical first-generation ...
Ching-Feng Wu, Po-Hsun Hou, Frank Chiahung Mao, Yao-Chi Su, Ching-Yang Wu, Wei-Cheng Yang, Chen-Si Lin, Hsiao-Pei Tsai, Huei-Jyuan Liao, Geng-Ruei Chang   +9 more
doaj   +1 more source

A Randomized Controlled Trial for Prevention of Postspinal Anesthesia Shivering in Gynecological Surgeries: Mirtazapine vs. Dexamethasone

Anesthesiology Research and Practice, 2022
Background. The frequency of shivering regarding regional anesthesia is 55%. Newer effective and tolerable options for postspinal anesthesia shivering (PSAS) prophylaxis are necessary to improve patients’ quality of care.
Ibrahim M. Esmat, Ahmed M. Elsayed, Hazem M. El-Hariri, Tarek M. Ashoor   +3 more
doaj   +1 more source

Brief report: Ketamine‐assisted “bridge therapy” for opioid tapering in complex cases

The American Journal on Addictions, EarlyView.
Abstract Background Opioid use disorder (OUD) presents major challenges, especially when combined with chronic pain and psychiatric comorbidities. A 25‐year‐old woman with OUD, chronic pain, and major depressive disorder underwent an 8‐week protocol of intravenous ketamine infusions (0.5 mg/kg weekly) as an adjunct to opioid tapering. Results Methadone
Mariana C. de Oliveira, Cláudia C. de Araujo Palmeira, André B. Negrão, Ziyad A. Hadi, Julia R. Arana, Rita de Cássia Ferreira Duarte, Joice L. P. da Silva, Gustavo K. Matsui, João F. D. Rapozero, Douglas H. Crispim, André Malbergier, João M. Castaldelli‐Maia   +11 more
wiley   +1 more source

The Assessment of Cytotoxicity and Genotoxicity of Mirtazapine in Human Blood Lymphocytes Using Micronucleus Test

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2015
Introduction: Tetracyclic antidepressants-mirtazapin is one of antidepressants drug that exhibits both noradrenergic and serotonergic activity. It is commonly used to treat major depressive disorder.
M Norizadeh tazehkand, M Topaktas
doaj