International Journal of Mycobacteriology, 2015 The advent of molecular typing using MIRU-VNTR mini-satellites has largely facilitated tuberculosis (TB) molecular epidemiological studies. Apart from detecting the chains of transmission and risk factors, these markers have also allowed to study the phenomena of mixed strain infections versus microevolutionary events.An initial set of Mycobacterium ...
Streit, Elisabeth +2 more
openaire +3 more sources
Genetic characterization of Mycobacterium tuberculosis in the West Bank, Palestinian Territories [PDF]
, 2012 BACKGROUND: The World Health Organization (WHO) declared human tuberculosis (TB) a global health emergency and launched the “Global Plan to Stop Tuberculosis” which aims to save a million lives by 2015.
Abedelmajeed Nasereddin +7 more
core +1 more source
Heterogeneity among Mycobacterium ulcerans isolates from Africa [PDF]
, 2006 Mycobacterium ulcerans causes Buruli ulcer, an ulcerative skin disease in tropical and subtropical areas. Despite restricted genetic diversity, mycobacterial interspersed repetitive unit-variable-number tandem repeat analysis on M.
Ablordey, A +8 more
core
Discriminatory ability of hypervariable variable number tandem repeat loci in population-based analysis of Mycobacterium tuberculosis strains, London, UK [PDF]
, 2009 To address conflicting results about the stability of variable number tandem repeat (VNTR) loci and their value in prospective molecular epidemiology of Mycobacterium tuberculosis, we conducted a large prospective population-based analysis of all M ...
Brown, T +3 more
core +3 more sources
Central Asian Journal of Global Health, 2014 Introduction. Methods of genotyping of M. tuberculosis play an important role in tuberсulosis (TB) infection control. These techniques are used to detect or exclude laboratory errors, control recurrent cases, and determine ways of TB transmission. Today,
Ainur Akhmetova +3 more
doaj +1 more source
Molecular typing of drug-resistant Mycobacterium tuberculosis strains from Turkey
Journal of Global Antimicrobial Resistance, 2020 Objectives: Appropriate antibiotic therapy and prevention of cross-contamination are the most important subjects in tuberculosis (TB) control. The aim of this study was to investigate the major phylogenetic clades and transmission rate of multidrug ...
Alper Karagoz +5 more
doaj +1 more source
Genomic sequencing is required for identification of tuberculosis transmission in Hawaii
BMC Infectious Diseases, 2018 Background Tuberculosis (TB) caused an estimated 1.4 million deaths and 10.4 million new cases globally in 2015. TB rates in the United States continue to steadily decline, yet rates in the State of Hawaii are perennially among the highest in the nation ...
Kent J. Koster +8 more
doaj +1 more source
High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations [PDF]
, 2017 Objectives The purpose of this study was to determine the levels of isoniazid and ethionamide resistance and to identify associated mutations in endemic multidrug-resistant (MDR) strains of Mycobacterium tuberculosis from the Lisbon metropolitan area ...
Boettger, Erik C. +7 more
core
Clinical use of Whole Genome Sequencing for Mycobacterium tuberculosis [PDF]
, 2016 Drug resistant tuberculosis (TB) remains a major challenge to global health and to healthcare in the UK. In 2014, England recorded 6520 cases of TB of which 1.4% were multi-drug resistant (MDR-TB).
A Hatem +45 more
core +1 more source
Beijing genotype is the most dominant genotype among clinical isolates of m.tuberculosis in Kazakhstan [PDF]
, 2014 Methods of genotyping of M. tuberculosis play important role in tuberculosis (TB) infection control. These techniques are used to detect or exclude laboratory errors, control recurrent cases and determine ways of TB transmission.
Akhmetova, А. +4 more
core +1 more source