The 24-loci mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) genotyping has been used as an international standard method for Mycobacterium tuberculosis (Mtb) genotyping. However, different optimized VNTR loci sets for
Shima Hadifar +15 more
doaj +1 more source
Uganda is among the 22 countries in the world with a high burden of tuberculosis. The southwestern region of the country has consistently registered a high TB/HIV incidence rate. This study is aimed at characterizing the Mycobacterium tuberculosis complex (MTBC) genotypic diversity in southwestern Uganda.
Lisa Nkatha Micheni +5 more
wiley +1 more source
Molecular epidemiology of tuberculosis in Western Burkina Faso: insights from a MIRU-VNTR study. [PDF]
Abstract Introduction : Tuberculosis (TB) remains a significant public health challenge in Burkina Faso, with limited molecular epidemiology data available to track strain diversity and transmission patterns.
Nagalo YYAA +14 more
europepmc +3 more sources
MIRU-VNTR allelic variability depends on Mycobacterium bovis clonal group identity [PDF]
The description of the population of M. bovis strains circulating in France from 1978 to 2013 has highlighted the discriminating power of the MLVA among predominant spoligotype groups. In the present study we aimed to characterize clonal groups via MLVA and to better understand the strain's population structure.
Hauer, Amandine +8 more
openaire +4 more sources
Molecular epidemiology of Mycobacterium bovis in Cameroon [PDF]
We describe the largest molecular epidemiological study of Bovine Tuberculosis (bTB) in a sub-Saharan African country with higher spatial resolution providing new insights into bTB. Four hundred and ninety-nine samples were collected for culture from 201
Asuquo, A. +13 more
core +2 more sources
Bioinformatic Analysis of MIRU-VNTR Repeats of Mycobacterium Tuberculosis Strains from Lagos, Nigeria [PDF]
The analysis of Mycobacterial Interpersed Repetitive Unit-Variable Number of Tandem Repeat (MIRU-VNTR) discriminates against the species of M. tuberculosis involved in the transmission of the disease. The reference method is the manual method. Our study involved developing a bioinformatics method of interpreting MIRU-VNTR and comparing it to the manual
Seydou Golo, Barro +4 more
openaire +2 more sources
Background Beijing sub-pedigree 2 (BSP2) and T sub-lineage 6 (TSL6) are two clades belonging to Beijing and T family of Mycobacterium tuberculosis (MTB), respectively, defined by Bayesian population structure analysis based on 24-loci mycobacterial ...
Peng-Kuan Liang +10 more
doaj +1 more source
Genetic diversity of Mycobacterium avium complex strains isolated in Argentina by MIRU-VNTR. [PDF]
SUMMARYMycobacterium aviumsp.avium(MAA),M. aviumsp.hominissuis(MAH), andM. aviumsp.paratuberculosis(MAP) are the main members of theM. aviumcomplex (MAC) causing diseases in several hosts. The aim of this study was to describe the genetic diversity of MAC isolated from different hosts.
Imperiale BR +8 more
europepmc +6 more sources
Effect of study design and setting on tuberculosis clustering estimates using Mycobacterial Interspersed Repetitive Units-Variable Number Tandem Repeats (MIRU-VNTR): a systematic review [PDF]
Objectives: To systematically review the evidence for the impact of study design and setting on the interpretation of tuberculosis (TB) transmission using clustering derived from Mycobacterial Interspersed Repetitive Units-Variable Number Tandem Repeats (
Abubakar, Ibrahim +4 more
core +3 more sources
Protection efficacy of Argentinian isolates of Mycobacterium avium subsp. paratuberculosis with different genotypes and virulence in a murine model [PDF]
Paratuberculosis is a chronic disease caused by Mycobacterium avium subsp. paratuberculosis (Map). The disease causes economic losses and, therefore, it is imperative to follow proper control strategies, which should include an effective vaccine. Several
Alvarado Pinedo, María Fiorella +8 more
core +1 more source

