Results 41 to 50 of about 4,208 (187)

MIRU-VNTR TECHNIQUE FOR MOLECULAR EPIDEMIOLOGICAL STUDIES OF TUBERCULOSIS

Tuberculosis and lung diseases, 2016
Goal of the study: to study the efficiency of using MIRU-VNTR molecular genetic technique for molecular epidemiological studies among pulmonary tuberculosis patients.Materials and methods: 20 patients with pulmonary tuberculosis relapses, 12 pulmonary tuberculosis patients with hetero-resistant results of drug susceptibility testing, 7 patients who ...
E. V. Аntusheva, I. V. Tarasova, P. I. Eliseev, A. O. Mariandyshe   +3 more
openaire   +3 more sources

Circulating strains of Mycobacterium tuberculosis: 24 loci MIRU-VNTR analysis in Bangladesh

Infection, Genetics and Evolution, 2020
Bangladesh is among the high burden countries for tuberculosis (TB) and multidrug resistant TB (MDR-TB). As the genetic diversity and distinct phylogeographic distribution of Mycobacterium tuberculosis are responsible for regional differences in drug resistance, this cross sectional study was conducted to identify the circulating M.
S M Shahriar, Rizvi, Shirin, Tarafder, Shaheda, Anwar, João, Perdigão, Fatima Tuj, Johora, Humayun, Sattar, S M Mostofa, Kamal   +6 more
openaire   +2 more sources

Determination of circulating Mycobacterium tuberculosis strains and transmission patterns among pulmonary TB patients in Kawempe municipality, Uganda, using MIRU-VNTR

BMC Research Notes, 2011
Background Mycobacterial interspersed repetitive units - variable number of tandem repeats (MIRU-VNTR) genotyping is a powerful tool for unraveling clonally complex Mycobacterium tuberculosis (MTB) strains and detection of transmission patterns.
Dickman Katherine R, Whalen Christopher C, Odong Paul R, Katabazi Fred A, Kateete David P, Nabyonga Lydia, Moses Joloba L   +6 more
doaj   +1 more source

Validation and comparative analysis of kogene mycobacterial interspersed repetitive unit-variable number of tandem repeat typing kit and its application on clinically isolated mycobacterium tuberculosis samples from national tuberculosis hospital, Republic of Korea

International Journal of Mycobacteriology, 2022
Background: Tuberculosis (TB) remains a serious public health burden in Korea. Mycobacterial Interspersed Repetitive Unit-Variable Number Tandem Repeat (MIRU-VNTR) is preferred for epidemiological TB investigation.
Jihee Jung, Taeuk Kang, Yoohyun Hwang, Sungweon Ryoo   +3 more
doaj   +1 more source

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study [PDF]

, 2017
SETTING: Implementation of novel diagnostic assays in tuberculosis (TB) laboratory diagnosis requires effective management of time and resources. OBJECTIVE: To further develop and assess at multiple centres a time-and-motion (T&M) tool as an objective ...
Drobniewski, FA, Folkvardsen D, D, Groenheit, R, Homorodean, D, Kodmon, C, Mathys., V, Nikolayevskyy, V, Raftery, P, Roycroft, E, Van der Werf, M, Vasiliauskiene, E   +10 more
core   +1 more source

Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies.

PLoS ONE, 2009
Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly
Iñaki Comas, Susanne Homolka, Stefan Niemann, Sebastien Gagneux   +3 more
doaj   +1 more source

Mycobacterium tuberculosisis the causative agent of tuberculosis in the southern ecological zones of Cameroon, as shown by genetic analysis [PDF]

, 2013
BACKGROUND: Tuberculosis (TB) is a major cause of mortality and suffering worldwide, with over 95% of TB deaths occurring in low- and middle-income countries.
Ane-Anyangwe Irene Ngoh, Emilienne Tata, Fidelis Cho-Ngwa, Inoster Nzuki, Jean Claude Tedom, Jean Paul Assam Assam, Juliette N Nyonka, Mercy Kitavi, Michel Toukam, Robert A Skilton, Roger Pelle, Vincent P K Titanji, Véronique Penlap Beng   +12 more
core   +1 more source

Molecular epidemiology in current times

Environmental Microbiology, Volume 22, Issue 12, Page 4909-4918, December 2020., 2020
Summary Motivated to find options for prevention or intervention, molecular epidemiology aims to identify the host and microbial factors that determine the transmission, manifestation and progression of infectious disease. The genotyping of cultivatable bacterial strains is performed by either anonymous fingerprinting techniques or sequence‐based ...
Burkhard Tümmler
wiley   +1 more source

Phylogenomic exploration of the relationships between strains of Mycobacterium avium subspecies paratuberculosis. [PDF]

, 2016
BACKGROUND: Mycobacterium avium subspecies paratuberculosis (Map) is an infectious enteric pathogen that causes Johne's disease in livestock. Determining genetic diversity is prerequisite to understanding the epidemiology and biology of Map. We performed
Bentley, Stephen D, Biet, Franck, Bryant, Josephine M, Harris, Simon R, Heron, Ian, Maskell, Duncan J, McLuckie, Joyce, Parkhill, Julian, Sevilla, Iker A, Smith, David GE, Stevenson, Karen, Thibault, Virginie C   +11 more
core   +9 more sources

Evaluation of customised lineage-specific sets of MIRU-VNTR loci for genotyping Mycobacterium tuberculosis complex isolates in Ghana.

PLoS ONE, 2014
BackgroundDifferent combinations of variable number of tandem repeat (VNTR) loci have been proposed for genotyping Mycobacterium tuberculosis complex (MTBC).
Adwoa Asante-Poku, Michael Selasi Nyaho, Sonia Borrell, Iñaki Comas, Sebastien Gagneux, Dorothy Yeboah-Manu   +5 more
doaj   +1 more source