Results 51 to 60 of about 4,208 (187)

ClassTR: Classifying Within-Host Heterogeneity Based on Tandem Repeats with Application to Mycobacterium tuberculosis Infections. [PDF]

, 2015
Genomic tools have revealed genetically diverse pathogens within some hosts. Within-host pathogen diversity, which we refer to as "complex infection", is increasingly recognized as a determinant of treatment outcome for infections like tuberculosis ...
Chindelevitch, L, Cohen, T, Colijn, C, Moodley, P, Wilson, D   +4 more
core   +3 more sources

Development of a hierarchical typing approach for Mycobacterium avium subsp. paratuberculosis (MAP) and characterization of MAP field cultures from Central Germany

Journal of Applied Microbiology, Volume 129, Issue 5, Page 1193-1206, November 2020., 2020
Abstract Aims Development of a novel hierarchical Mycobacterium avium subsp. paratuberculosis (MAP) typing approach and characterization of MAP field cultures in Central Germany. Methods and Results By combining single nucleotide polymorphisms (SNPs) and mycobacterial interspersed repetitive unit‐variable number tandem repeat, we developed a highly ...
A. Fawzy, M. Zschöck, C. Ewers, T. Eisenberg   +3 more
wiley   +1 more source

Possible Transmission Mechanisms of Mixed Mycobacterium tuberculosis Infection in High HIV Prevalence Country, Botswana

Emerging Infectious Diseases, 2020
Tuberculosis caused by concurrent infection with multiple Mycobacterium tuberculosis strains (i.e., mixed infection) challenges clinical and epidemiologic paradigms.
Yeonsoo Baik, Chawangwa Modongo, Patrick K. Moonan, Eleanor S. Click, James L. Tobias, Rosanna Boyd, Alyssa Finlay, John E. Oeltmann, Sanghyuk S. Shin, Nicola M. Zetola   +9 more
doaj   +1 more source

Tuberculosis Microepidemics among Dispersed Migrants, Birmingham, UK, 2004-2013 [PDF]

, 2015
MIRU-VNTR typing was supported by the Public Health England National TB Strain Typing Project. M.M. is funded by the UK Clinical Research Collaboration Modernising Medical Microbiology Consortium. C.B.
Alland, Allix-Béguec, Catherine Browne, Cook, E. Grace Smith, Glynn, Heinke Kunst, Jackson, Jason T. Evans, Kruijshaar, Love, Martin J. Dedicoat, Mears, Melinda L. Munang, Peter M. Hawkey, Shaina Khanom, Sloot, Small, Steven B. Welch, Walker   +19 more
core   +1 more source

Spoligotype Variation of Mycobacterium tuberculosis Strains Prevailing in Korea

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2020, Issue 1, 2020., 2020
Tuberculosis (TB) is an ongoing global health problem, including in South Korea. To manage TB efficiently, it is necessary to understand the epidemiology, transmission route, and characteristics of prevailing Mycobacterium tuberculosis strains. In this study, we investigated microevolutions over time in the spoligotype patterns of M.
Seung-Eun Song, Dong Hyeok Kim, Seong-Han Kim, Mi-Sun Park, Sang-Hee Park, Kil-Soo Lee, Caetano Antunes   +6 more
wiley   +1 more source

Genetic diversity of the Mycobacterium tuberculosis Beijing family based on SNP and VNTR typing profiles in Asian countries. [PDF]

PLoS ONE, 2012
The Mycobacterium tuberculosis (MTB) Beijing strain is highly virulent, drug resistant, and endemic over Asia. To explore the genetic diversity of this family in several different regions of eastern Asia, 338 Beijing strains collected in Taiwan (Republic
Yih-Yuan Chen, Jia-Ru Chang, Wei-Feng Huang, Shu-Chen Kuo, Ih-Jen Su, Jun-Ren Sun, Tzong-Shi Chiueh, Tsi-Shu Huang, Yao-Shen Chen, Horng-Yunn Dou   +9 more
doaj   +1 more source

Novel single nucleotide polymorphism-based assay for genotyping Mycobacterium avium subsp. paratuberculosis [PDF]

, 2016
Typing of Mycobacterium avium subspecies paratuberculosis strains presents a challenge, since they are genetically monomorphic and traditional molecular techniques have limited discriminatory power.
Bryant, Josephine, Goldstone, Robert J., Inácio, João, Leão, Célia, McLuckie, Joyce, Smith, David G.E., Stevenson, Karen   +6 more
core   +2 more sources

Mycobacterium tuberculosis Central Asian Strain (CAS) lineage strains in Pakistan reveal lower diversity of MIRU loci than other strains

International Journal of Mycobacteriology, 2014
Mycobacterium tuberculosis (MTB) Central Asian Strain (CAS) lineage strains are predominant in South Asia. Mycobacterial interspersed repetitive units-variable number of tandem repeats (MIRU-VNTR) typing is an effective way of determining genetic ...
Asho Ali, Zahra Hasan, Sana Jafri, Raunaq Inayat, Rumina Hasan   +4 more
doaj   +1 more source

Molecular characterization of mycobacterium tuberculosis complex isolates in Mozambique [PDF]

, 2015
Mozambique is one of the high burden tuberculosis (TB) and human immunodeficiency virus (HIV) countries with a prevalence of HIV infection in adults of 11.5% and an estimated TB prevalence of 559 per 100 000 population.
Viegas, Sofia Omar
core   +1 more source

Molecular diversity of Mycobacterium tuberculosis complex in Sikkim, India and prediction of dominant spoligotypes using artificial intelligence

Scientific Reports, 2021
In India, tuberculosis is an enormous public health problem. This study provides the first description of molecular diversity of the Mycobacterium tuberculosis complex (MTBC) from Sikkim, India.
Kangjam Rekha Devi, Jagat Pradhan, Rinchenla Bhutia, Peggy Dadul, Atanu Sarkar, Nitumoni Gohain, Kanwar Narain   +6 more
doaj   +1 more source