Results 81 to 90 of about 4,208 (187)
Reproducibility of 15-Loci MIRU-VNTR Method in Mycobacterium tuberculosis Genotyping
Background: Mycobacterium tuberculosis genotyping is an essential step for understanding the epidemiology of tuberculosis. Mycobacterial-interspersed-repetitive-units (MIRU)-variable-number-of-tandem-repeats (VNTR) typing is an important method for this purpose.
Maya Babai Kochkaksaraei +2 more
openaire +2 more sources
Mycobacterium tuberculosis Next‐Generation Whole Genome Sequencing: Opportunities and Challenges
Mycobacterium tuberculosis drug resistance is a threat to global tuberculosis (TB) control. Comprehensive and timely drug susceptibility determination is critical to inform appropriate treatment of drug‐resistant tuberculosis (DR‐TB). Phenotypic drug susceptibility testing (DST) is the gold standard for M. tuberculosis drug resistance determination. M.
Thato Iketleng +8 more
wiley +1 more source
Background The phenomenon of misdiagnosing tuberculosis (TB) by laboratory cross-contamination when culturing Mycobacterium tuberculosis (MTB) has been widely reported and it has an obvious clinical, therapeutic and social impact.
de Viedma Darío +5 more
doaj +1 more source
A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]
Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A +7 more
core +1 more source
Molecular epidemiology analyses are frequently used in determining epidemiology of tuberculosis. Recently, Mycobacterial Interspersed Repetitive Unit Variable Number Tandem Repeat (MIRU-VNTR) and Spoligotyping has become an important method, as it allows high-through put, discriminatory and reproducible analysis of clinical isolate. The purpose of this
Mehdi, Jafarian +5 more
openaire +1 more source
Mycobacterium Tuberculosis Genotyping Using MIRU-VNTR Typing
Background and purpose: Tuberculosis is among the leading causes of death from infectious diseases in the world. According to World Health Organization (WHO), the estimated rate of TB in Iran was 21 per 100,000 populations in 2015. The present study was designed to evaluate the genetic diversity and transmission dynamics of Mycobacterium tuberculosis ...
Taher Azimi +6 more
openaire +1 more source
Tuberculosis (TB) is a deadly infection and caused 1.4 million deaths in 2018. Assessing the geographic distribution of major lineages of Mycobacterium tuberculosis can contribute greatly to TB control. Mycobacterial interspersed repetitive unit variable
S.M.J. Mousavi +6 more
doaj +1 more source
Genotyping of ClinicalMycobacterium tuberculosisIsolates Based on IS6110and MIRU-VNTR Polymorphisms [PDF]
In this study, 155 clinicalMycobacterium tuberculosisisolates were subject to genotyping with fast ligation-mediated PCR (FLiP). This typing method is a modified mixed-linker PCR, a rapid approach based on the PCR amplification ofHhaI restriction fragments of genomic DNA containing the 3′ end of IS6110and resolving the amplicons by polyacrylamide gel ...
Żaczek, Anna +4 more
openaire +2 more sources
Dynamics of Mycobacterium tuberculosis Lineages in Oman, 2009 to 2018
Study aim. Effective Tuberculosis (TB) control measures in Oman have reduced the annual incidence of tuberculosis cases by 92% between 1981 and 2016. However, the current incidence remains above the program control target of
Sara Al-Mahrouqi +12 more
doaj +1 more source
Wild boar tuberculosis in Iberian Atlantic Spain: a different picture from Mediterranean habitats [PDF]
BACKGROUND Infections with Mycobacterium bovis and closely related members of the Mycobacterium tuberculosis complex (MTC) are shared between livestock, wildlife and sporadically human beings. Wildlife reservoirs exist worldwide and can interfere with
Amado, Javier +12 more
core +3 more sources

