The Potential Clinical and Economic Value of Primary Tumour Identification in Metastatic Cancer of Unknown Primary Tumour: A Population-Based Retrospective Matched Cohort Study. [PDF]
PurposeSeveral genomic tests have recently been developed to identify the primary tumour in cancer of unknown primary tumour (CUP). However, the value of identifying the primary tumour in clinical practice for CUP patients remains questionable and ...
Brackstone, Muriel +8 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The ESHRE/ESGE consensus on the classification of female genital tract congenital anomalies,
STUDY QUESTION What classification system is more suitable for the accurate, clear, simple and related to the clinical management categorization of female genital anomalies?
G. Grimbizis +10 more
semanticscholar +1 more source
Focal Spot, Fall/Winter 1997 [PDF]
https://digitalcommons.wustl.edu/focal_spot_archives/1077/thumbnail ...
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
A review on agrowaste based activated carbons for pollutant removal in wastewater systems
Environmental pollution from chemicals utilized in manufacturing, pharmaceuticals, and chemical process industries is of serious concern nowadays due to the contamination that ensues when these chemicals are discharged into water bodies. Activated carbon
K. Okiy +2 more
semanticscholar +1 more source
Dairy Resource Management: A Comparison of Conventional and Pasture-Based Systems [PDF]
Facing rapid and significant change in the sector, U.S. dairy production trends from 1993-2005 were tracked and performance measures (scale and technical efficiency and returns on assets) were estimated for conventional and pasture-based dairy farms ...
Gillespie, Jeffrey M. +3 more
core +1 more source
National Authority for Health: France [PDF]
Provides an overview of France's National Authority for Health, which defines best-care standards and assesses the benefit and effectiveness of new technologies for inclusion on benefits lists.
Bertrand Xerri, Lise Rochaix
core
Evaluation of combination therapy for Burkholderia cenocepacia lung infection in different in vitro and in vivo models [PDF]
Burkholderia cenocepacia is an opportunistic pathogen responsible for life-threatening infections in cystic fibrosis patients. B. cenocepacia is extremely resistant towards antibiotics and therapy is complicated by its ability to form biofilms.
Brackman, Gilles +10 more
core +4 more sources

