Results 91 to 100 of about 32,684 (231)
Nature Communications, 2023 The c.2299delG mutation in usherin causes loss of hearing and vision. Here, the authors show in a mouse model of this disease that the expression of mutant usherin leads to retinitis pigmentosa and structural defects in the photoreceptor cilium ...
Lars Tebbe +7 more
doaj +1 more source
Perisaccadic perceptual mislocalization is different for upward saccades [PDF]
Journal of Neurophysiology, 2017 Saccadic eye movements, which dramatically alter retinal images, are associated with robust perimovement perceptual alterations. Such alterations, thought to reflect brain mechanisms for maintaining perceptual stability in the face of saccade-induced retinal image disruptions, are often studied by asking subjects to localize brief stimuli presented ...
Grujic, Nikola +4 more
openaire +2 more sources
Making Two out of One: Kinesin Motors Driving Plant Cell Division
Cytoskeleton, EarlyView.ABSTRACT The Kinesin superfamily of microtubule dependent motors is present in all eukaryotes. Not all of the subfamilies are represented in all kingdoms, and the ones that are do not always show conserved functions. Tight control of the cytoskeleton is essential for proper progression and completion of mitosis and cytokinesis, and key functions are ...
Choy Kriechbaum, Sabine Müller
wiley +1 more source
Illusory motion and mislocalization of temporally offset target in apparent motion display
Frontiers in Psychology, 2013 When a visual target briefly appears in a display containing visual motion information, the perceived position of the target is mislocalized forward along its direction of motion.
Souta eHidaka +2 more
doaj +1 more source
VKORC1 ER mislocalization causes rare disease
Blood, 2014 In this issue of Blood , Czogalla et al identify that the rare heritable hemorrhaging disease, vitamin K–dependent clotting factor deficiency type 2 (VKCFD2), is caused by mislocalization of vitamin K epoxide reductase (VKORC1) in the endoplasmic reticulum (ER).[1][1] ![Figure][2 ...
openaire +3 more sources
Cytoskeleton, EarlyView.ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong +7 more
wiley +1 more source
Journal of Biomedical Science, 2012 Background Astrocytomas are cancers of the brain in which high levels of extracellular glutamate plays a critical role in tumor growth and resistance to conventional treatments.
Varini Karine +6 more
doaj +1 more source
Neuronal RNA‐binding protein dysfunction in multiple sclerosis cortex
Annals of Clinical and Translational Neurology, 2020 Objective Neurodegeneration is thought to be the primary cause of neurological disability in multiple sclerosis (MS). Dysfunctional RNA‐binding proteins (RBPs) including their mislocalization from nucleus to cytoplasm, stress granule formation, and ...
Hannah E. Salapa +3 more
doaj +1 more source
Acta Neuropathologica Communications, 2018 Spinocerebellar ataxia type 14 (SCA14) is a subtype of the autosomal dominant cerebellar ataxias that is characterized by slowly progressive cerebellar dysfunction and neurodegeneration.
M. M. Wong +9 more
semanticscholar +1 more source
Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle
Developmental Dynamics, EarlyView.Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell +3 more
wiley +1 more source