Results 91 to 100 of about 31,078 (242)
Movement Disorders Clinical Practice, EarlyView.Abstract Background Neurodegeneration with Brain Iron Accumulation (NBIA) is a heterogeneous group of heritable, mostly recessive, progressive neurodegenerative diseases characterized by iron deposition in the basal ganglia and brainstem. There are no solid global epidemiological data on prevalence and incidence of NBIA subtypes, but registry data and ...
Susanne A. Schneider +3 more
wiley +1 more source
Deficiency in class III PI3-kinase confers postnatal lethality with IBD-like features in zebrafish
Nature Communications, 2018 The functions of the class III PI3-kinase (PIK3C3) in gut homeostasis and innate immunity are poorly understood. Here the authors show that PIK3C3-deficient zebrafishes develop intestinal injury and inflammation due to mislocalization of cell junction ...
Shaoyang Zhao +12 more
doaj +1 more source
Dataset for reproducing the Fig.6 of paper "A circuit model for transsaccadic space updating and mislocalization"(preprint: https://www.biorxiv.org/content/10.1101/2024.10.27.620527v1).
WANG, XIAO
core +1 more source
Protein Glutamylation: From Cytoskeleton to Signaling
Med Research, EarlyView.Tubulin glutamylation, γ‐glutamylation, and nontubulin glutamylation are distinct yet interconnected post‐translational modifications that regulate diverse physiological and pathological processes, including cytoskeletal organization, cell cycle progression, immunity, metabolism, and disease development.
Jiayuan Chen +4 more
wiley +1 more source
A nanobody-based toolset to investigate the role of protein localization and dispersal in Drosophila
eLife, 2017 The role of protein localization along the apical-basal axis of polarized cells is difficult to investigate in vivo, partially due to lack of suitable tools.
Stefan Harmansa +4 more
doaj +1 more source
Interaction of histone H4 with Cse4 facilitates conformational changes in Cse4 for its sumoylation and mislocalization. [PDF]
Mislocalization of overexpressed CENP-A (Cse4 in budding yeast, Cnp1 in fission yeast, CID in flies) contributes to chromosomal instability (CIN) in yeasts, flies, and human cells. Mislocalization of CENP-A is observed in many cancers and this correlates
Kazi, Amira +5 more
core +1 more source
Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity
VIEW, EarlyView.Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin +3 more
wiley +1 more source
Mislocalization of TDP-43 in TMEV-infected cultured cells.
, 2019 (A, D, E) Immunofluorescent staining of TDP-43, PTB1, and FUS in BHK-21 cells at 8 HPI. (A) TDP-43 is located in the nucleus of mock-infected (VP1-negative) cells.
Peter Pytel (358923) +4 more
core +1 more source
Identification of Yeast Protein Sequences With Similarity to the ESCRT‐III Protein Snf7
Yeast, EarlyView.ABSTRACT Endosomal sorting complex required for transport (ESCRT‐III) is a membrane remodeling complex involved in a large number of cellular processes. It appears to perform an essential function in eukaryotes, since to date no eukaryotic organism completely devoid of ESCRT‐III has been found.
Thomas Brune, Ralf Kölling
wiley +1 more source
Visual space constructed by saccade motor maps
Frontiers in Human Neuroscience, 2016 How visual space is represented in the brain is an open question in neuroscience. Embodiment theories propose that spatial perception is structured by neural motor maps.
Eckart Zimmermann, Markus Lappe
doaj +1 more source