Results 81 to 90 of about 29,309 (251)

Cross-Sectional Analysis of Immunohistochemical Expression of Mismatch Repair  Proteins in Prostate Cancer

open access: yesPakistan Armed Forces Medical Journal
Objective: To determine the immunohistochemistry-based frequency of mismatch repair protein (MSH-2, MSH-6, MLH-1 & PMS-2) deficiency in prostate cancer. Study Design: Cross-sectional study.
Muhammad Atif Khalil   +6 more
doaj   +1 more source

Development of a Three‐Axis Planar Hall Magnetoresistance Sensor Using a Superparamagnetic Nanoparticle‐Based Flux Guide

open access: yesAdvanced Functional Materials, EarlyView.
A printed superparamagnetic nanoparticle‐based flux guide enables the realization of a hysteresis‐free three‐axis magnetic sensor. This innovative architecture efficiently redirects out‐of‐plane fields to planar sensing elements, facilitating simultaneous vector detection without complex reset protocols.
Changyeop Jeon   +10 more
wiley   +1 more source

Biodegradable and Biocompatible Functional Polymers for Biomedical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han   +5 more
wiley   +1 more source

High‐Performance n‐Type Organic Thermoelectrics Enabled by Control Over Microstructure, Orientation and Contact Plane in Naphthalenediimide‐Bithiazole‐Copolymer Films

open access: yesAdvanced Functional Materials, EarlyView.
Effective control over the crystalline contact plane and microstructure of a naphthalenediimide‐bithiazole copolymer enables high‐performance n‐type thermoelectrics. While rubbing alignment induces a detrimental edge‐on orientation, subsequent solvent vapor‐induced re‐orientation facilitates a favorable mixed face‐on/edge‐on morphology.
Suhao Wang   +13 more
wiley   +1 more source

Electrostatic Superlattices Beyond 1:1 Stoichiometry

open access: yesAdvanced Functional Materials, EarlyView.
Polymer‐mediated charge regulation drives two hierarchical routes to higher‐stoichiometry nanoparticle superlattices. Tuning the polymer's molecular weight promotes progressive interstitial filling, transforming ZnS into the fully occupied CaF2${\rm CaF}_2$ lattice. Exchanging polymer assignment between large and small nanoparticles instead breaks CsCl
Binay P. Nayak   +7 more
wiley   +1 more source

Microsatellite instability and mismatch repair protein deficiency: equal predictive markers?

open access: yesPathology and Oncology Research
Current clinical guidelines recommend mismatch repair (MMR) protein immunohistochemistry (IHC) or molecular microsatellite instability (MSI) tests as predictive markers of immunotherapies.
Maja L. Nádorvári   +4 more
doaj   +1 more source

Snap‐Through–Driven Liquid Crystal Elastomers for High‐Power Remote Microneedle Actuation Toward Smart Livestock Systems

open access: yesAdvanced Functional Materials, EarlyView.
A magnetically assisted snap‐through liquid crystal elastomer transforms photochemical deformation into a high‐power mechanical impulse, enabling remote microneedle actuation and highlighting its potential for future smart livestock intervention systems.
Chae Won Lee   +3 more
wiley   +1 more source

The Mystery of Mismatch Repair Deficiency: Lynch or Lynch-like? [PDF]

open access: yesGastroenterology, 2013
Syndromic familial colorectal cancer (CRC) has gone through an evolution of names, and at this time, we refer to Lynch syndrome as the familial syndrome characterized by a germline mutation in a DNA mismatch repair (MMR) gene1. This helped distinguish Lynch syndrome from other familial collections of tumors that were not linked to MMR gene mutations ...
openaire   +2 more sources

Chemical Control of Space Charge Barriers and Grain Boundary Resistances in Polycrystalline Ionic Conductors

open access: yesAdvanced Functional Materials, EarlyView.
Grain boundaries (GBs) in polycrystalline materials often block charge transport and drive degradation. Using Gd‐doped CeO2 as a model electrolyte used in fuel/electrolysis cells, we developed a core‐shell infiltration method to selectively modify GB chemistry and space charge potential, achieving orders‐of‐magnitude ionic conductivity changes.
Z. Sha   +5 more
wiley   +1 more source

Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background Muir‐Torre syndrome is defined by the development of sebaceous skin lesions in individuals who carry a germline mismatch repair (MMR) gene mutation.
Peter Georgeson   +10 more
doaj   +1 more source

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