Results 41 to 50 of about 28,640 (298)

A markup interpretation of optimal rules for irreversible investment [PDF]

open access: yes, 1997
We re-examine the basic investment problem of deciding when to incur a sunk cost to obtain a stochastically fluctuating benefit. The optimal investment rule satisfies a trade-off between a larger versus a later net benefit; we show that this trade-off is
Sødal, Sigbjørn   +2 more
core  

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Discounting rules for risky assets [PDF]

open access: yes, 1986
This paper develops a rule for calculating a discount rate to value risky projects. The rule assumes that the asset risk can be measured by a single index (e.g., beta), but makes no other assumptions about specific form of the asset pricing model ...
Myers, Stewart C., Ruback, Richard S.
core  

Die Rule of Law im Völker- und im Europarecht – aktuelle Probleme

open access: yesAustrian Law Journal, 2015
Diese am 5. März 2015 in Graz gehaltene Antrittsvorlesung eines Praxisprofessors, der im Hauptberuf Leiter des Völkerrechtsbüros im österreichischen Außenministerium ist, beschäftigt sich mit dem Begriff der Herrschaft des Rechts in den internationalen ...
Helmut Tichy
doaj   +2 more sources

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Optimizing the Detection of Characteristic Waves in ECG Based on Processing Methods Combinations

open access: yesIEEE Access, 2018
Accurate detection of characteristic electrocardiogram (ECG) waves is necessary for ECG analysis and interpretation. In this paper, we distinguish four processing steps of detection algorithms: noise and artifacts reduction, transformations, fiducial ...
Kresimir Friganovic   +4 more
doaj   +1 more source

A Comparative Study of Control Methods for X3D Quadrotor Feedback Trajectory Control

open access: yesApplied Sciences, 2022
Unmanned aerial vehicles (UAVs), particularly quadrotor, have seen steady growth in use over the last several decades. The quadrotor is an under-actuated nonlinear system with few actuators in comparison to the degree of freedom (DOF); hence, stabilizing
Tanzeela Shakeel   +6 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Perancangan dan Simulasi MRAC untui Proses Pengendalian Temperatur pada Continuous Stirred Tank Reactor (CSTR)

open access: yesJurnal Teknik ITS, 2014
Temperatur merupakan salah satu variabel proses dasar yang dikendalikan untuk menjaga suhu cairan di dalam reaktor. Model Reference Adaptive Controller (MRAC) dengan MIT rule dipilih untuk mencapai spesifikasi respon yang diinginkan pada CSTR. Beban yang
Amelia Sylvia   +2 more
doaj  

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