Results 71 to 80 of about 28,640 (298)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Is the Taylor Rule Really Different from the McCallum Rule?
When base velocity is a stable function of the Federal funds rate (FFR), the money base-nominal GDP targeting rule (McCallum rule) can be reparameterized and presented in terms of FFR as the policy instrument.
W. A. Razzak
core +1 more source
RColSim: An R-Based Open-Source Regional Water Management Model for the Columbia River Basin
Journal of Open Research SoftwareWe present RColSim, a script-based water management model that simulates the operation of reservoir systems of the Columbia River Basin located in the Pacific Northwest.
Keyvan Malek +5 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
AMORD: A Deductive Procedure System [PDF]
, 1977 This research was conducted at the Artificial Intelligence Laboratory of the Massachusetts Institute of Technology. Support for the Laboratory's artificial intelligence research is provided in part by the Advanced Research Projects Agency of the ...
de Kleer, Johan +4 more
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Local Universal Rule-based eXplainer (LUX)
SoftwareXLUX (Local Universal Rule-Based Explainer) is an explainable artificial intelligence (XAI) method that produces explanations for any type of machine-learning model designed particularly for the tabular data.
Szymon Bobek, Grzegorz J. Nalepa
doaj +1 more source
Healthcare Technology Letters, 2019 This work investigates the application of zero-frequency resonator (ZFR) for detecting systolic peaks of photoplethysmogram (PPG) signals. Based on the authors’ studies, they propose an automated noise-robust method, which consists of the central ...
Simhadri Vadrevu +1 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The Rule of Law and the Eastern Enlargement of the EU [PDF]
, 2001 This thesis examines and analyses the 'rule of law' concept and its importance to the enlargement of the European Union to include Central and Eastern European countries.
Mineshima, Dale Sachiko Oi Lin Nalani
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