Results 121 to 130 of about 618,328 (350)

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

open access: yesBMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng   +10 more
wiley   +1 more source

Epidemiology of post-craniotomy headache (EPoCH): a multicenter retrospective study

open access: yesBrain and Spine, 2021
Y. Shibata   +6 more
doaj   +1 more source

Does Intramedullary Reaming in Total Knee Arthroplasty Increase Postoperative Bleeding? A Propensity Score–Matched Cohort Study

open access: yesArthroplasty Today
Background: There is conflicting evidence about whether avoiding medullary canal reaming of the femur during total knee arthroplasty (TKA) reduces blood loss.
Sachiyuki Tsukada, MD, PhD   +5 more
doaj   +1 more source

Import pathways of precursor proteins into mitochondria [PDF]

open access: yes, 1988
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Neupert, Walter   +4 more
core  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

open access: yesBMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang   +12 more
wiley   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma   +9 more
wiley   +1 more source

Force stimulation promotes nerve regeneration by restoring cellular energy

open access: yesBMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang   +10 more
wiley   +1 more source

Review of Elisabeth Crouzet-Pavan, Venezia trionfante. Gli orizzonti di un mito, Einaudi, Torino, 2001 (Venise triomphante. Les horizons d'un mythe, Éditions Albin Michel, Paris, 1999) [PDF]

open access: yes, 2005
CR de Elisabeth Crouzet-Pavan, Venezia trionfante. Gli orizzonti di un mito, Einaudi, Torino, 2001 (Venise triomphante. Les horizons d'un mythe, Éditions Albin Michel, Paris, 1999)Recensione di Elisabeth Crouzet-Pavan, Venezia trionfante.
Santarelli, Daniele
core   +2 more sources

Mito y pedagogía

open access: yesPraxis & Saber, 2015
<p>En estas primeras décadas del siglo XXI poner en relación los vocablos «mito» y «pedagogía» no es ningún despropósito, especialmente si se parte de la base que el mito fundamentalmente es narración en acto. Ha de subrayarse el hecho de que, desde el nacimiento hasta la muerte, el narrar es —debería ser— un factor constituyente en todas las ...
openaire   +4 more sources

Integrated spherical nucleic acid nanoreactor mobilizes targeted PD‐L1 proteolysis and cuproptosis for robust breast cancer immunotherapy

open access: yesBMEMat, EarlyView.
This study provides an integrated spherical nucleic acid nanoreactor (denoted as AMCuD) for targeted PD‐L1 degradation and chemo‐dynamically enhanced cuproptosis to synergically elicit robust immunotherapy against the triple‐negative breast cancer (TNBC) growth, recurrence and metastasis.
Ningxi Li   +9 more
wiley   +1 more source

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