Results 151 to 160 of about 616,240 (353)

Mitochondria and the Actin Cytoskeleton in Neurodegeneration

open access: yesCytoskeleton, EarlyView.
ABSTRACT Mitochondrial dysfunction and cytoskeletal disorganization are widely recognized hallmarks of neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS).
Shivani Tuli   +3 more
wiley   +1 more source

The amount of femorotibial alignment correction through total knee arthroplasty may affect postoperative hindfoot alignment

open access: yesJournal of Experimental Orthopaedics
Purpose This study was performed to investigate the relationship between the amount of femorotibial alignment correction and the amount of improvement of hindfoot alignment in total knee arthroplasty (TKA).
Tsutomu Nakayama   +6 more
doaj   +1 more source

Peach Kernel Oil Modulates Lipid Metabolism Disorder in ApoEa CRISPR/Cas9 Gene‐Disrupted Zebrafish

open access: yesFood Frontiers, EarlyView.
In this study, we used CRISPR/Cas9 gene editing technology to establish a lipid metabolism disorder model of ApoEa mutant zebrafish. We applied peach kernel oil to this model and studied the mechanism of peach kernel oil regulating lipid disorder in combination with transcriptomics.
Lei Xia   +14 more
wiley   +1 more source

Agilent Seahorse XF HS Mini‐Platform: A Comprehensive Guide for Real‐Time Analysis of Cellular Energy Metabolism

open access: yesFood Safety and Health, EarlyView.
This comprehensive guide for the Agilent Seahorse XF HS Mini‐platform presents real‐time analysis of cellular energy metabolism across the mitochondrial stress test, glycolytic rate assay, and real‐time ATP rate assay, with applications in food safety and health and in metabolic disease.
Zhihao Liu   +3 more
wiley   +1 more source

Hemothorax after chest tube insertion for pneumothorax as a complication of clopidogrel

open access: yesOpen Medicine, 2013
Ohara Gen   +4 more
doaj   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

open access: yesiNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong   +5 more
wiley   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

open access: yesInterdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui   +12 more
wiley   +1 more source

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